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Medicine overview
Indications of Pedeamin 100 ml
Diphenhydramine is indicated for the treatment of followings:
Seasonal, perennial, vasomotor rhinitis
Urticaria, angioneurotic oedema, anaphylaxis
Pruiritic conditions
Premedication for emesis and motion sickness
Miscellaneous like meniere's disease and parkinsonism
Theropeutic Class
Sedating Anti-histamine
Pharmacology
Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.
Dosage & Administration of Pedeamin 100 ml
Adult-
Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.
Children-
1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day
Dosage of Pedeamin 100 ml
Adult-
Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.
Children-
1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day
Interaction of Pedeamin 100 ml
Diphenhydramine administration significantly reduces the absorption of the antituberculous agent para-aminosalicyclic acid (PAS) from the gastrointestinal tract. CNS depressants may potentiate the sedative action of Diphenhydramine. Anticholinergic drugs may potentiate Diphenhydramine’s anticholinergic side effects.
Contraindications
Known hypersensitivity to Pedeamin 100 ml, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.
Side Effects of Pedeamin 100 ml
Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.
Pregnancy & Lactation
Category B: There are no adequate and well controlled studies in pregnant women using Pedeamin 100 ml. Therefore, Pedeamin 100 ml should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of Pedeamin 100 ml in lactating mother is not recommended.
Precautions & Warnings
Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.
Overdose Effects of Pedeamin 100 ml
Symptoms: Impaired consciousness; psychosis, seizures, antimuscarinic symptoms (e.g. mydriasis, tachycardia, tachyarrhythmias), resp failure, rhabdomyolysis; acute delirium with visual and auditory hallucination (topical). Management: Supportive and symptomatic treatment. Convulsions and marked CNS stimulation may be treated with IV diazepam.
Storage Conditions
Store between 15-30° C. Protect from moisture.
Drug Classes
Sedating Anti-histamine
Mode Of Action
Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.
Pregnancy
Category B: There are no adequate and well controlled studies in pregnant women using Pedeamin 100 ml. Therefore, Pedeamin 100 ml should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of Pedeamin 100 ml in lactating mother is not recommended.
Frequently Asked Questions
What is Pedeamin 100 ml used for?
Diphenhydramine is indicated for the treatment of followings: Seasonal, perennial, vasomotor rhinitis Urticaria, angioneurotic oedema, anaphylaxis Pruiritic conditions Premedication for emesis and motion sickness Miscellaneous like meniere's disease and parkinsonism
What is the dosage of Pedeamin 100 ml?
Adult- Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night. Children- 1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day
What are the side effects of Pedeamin 100 ml?
Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.
Who should not take Pedeamin 100 ml?
Known hypersensitivity to Pedeamin 100 ml, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.
What precautions should be taken with Pedeamin 100 ml?
Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.
Is Pedeamin 100 ml safe during pregnancy and breastfeeding?
Category B: There are no adequate and well controlled studies in pregnant women using Pedeamin 100 ml. Therefore, Pedeamin 100 ml should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of Pedeamin 100 ml in lactating mother is not recommended.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.