Levocar

Levocar330 mg

Tablet

Levocarnitine

Square Pharmaceuticals PLC.

Product Code : 9417
MRP 5.03
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Medicine overview

Indications of Levocar 330 mg

Levocar 330 mg is indicated in- Chronic Fatigue Syndrome Heart Diseases Congestive Heart Failure Kidney Disease High Cholesterol Intermittent Claudication Dementia and memory impairment Down Syndrome Male infertility Hyperthyroidism

Theropeutic Class

Drugs for muscular energy metabolism

Pharmacology

Levocar 330 mg is a naturally occurring substance required in mammalian energy metabolism. It has been shown to facilitate long-chain fatty acid entry into cellular mitochondria, thereby delivering substrate for oxidation and subsequent energy production in the form of Adenosine Tri phosphate or ATP. Fatty acids are utilized as an energy substrate in all tissues except the brain. In skeletal and cardiac muscle, fatty acids are the main substrate for energy production.

Dosage & Administration of Levocar 330 mg

Tablet- Adults: The recommended oral dosage for adults is 990 mg, two or three times a day using the 330 mg tablets, depending on clinical response. Infants and children: The recommended oral dosage for infants and children is between 50 and 100 mg/kg/day in divided doses, with a maximum of 3 g/day. Dosage should begin at 50 mg/kg/day. The exact dosage will depend on clinical response. Monitoring should include periodic blood chemistries, vital signs, plasma carnitine concentrations and overall clinical condition.Syrup- Adults: 10 to 30 ml/day. Dosage should start at 10 ml/day in divided doses, and be increased slowly while assessing tolerance and therapeutic response. Infants and children: 50 to 100 mg/kg/day which is equivalent to 0.5 ml/kg/day. Dosage should start at 50 mg/kg/day, and be increased slowly to a maximum of 3 g/day (30 ml/day) while assessing tolerance and therapeutic response. Solution may be consumed alone or dissolved in drink or other liquid food. Doses should be spaced evenly throughout the day (every three or four hours) preferably during or following meals and should be consumed slowly in order to maximize tolerance.

Dosage of Levocar 330 mg

Levocar 330 mg tablet- Adults: 330 mg two or three times daily. Depending on clinical response. Infants and children: 50 to 100 mg/kg/day in divided doses, with a maximum of 3 g/day. Dosage should begin at 50 mg/kg/day. The exact dosage will depend on clinical response. Levocar 330 mg solution (For oral use only. Not for parenteral use)- Adults: The recommended dosage of Levocar 330 mg 100 ml solution is 10 to 30 ml/day. Higher doses should be administered with caution. Dosage should be started at 10 ml/day and be increased slowly while assessing tolerance and therapeutic response. Infants and children: The recommended dosage of Levocar 330 mg 100 ml solution is 50 to 100 mg/kg/day. Dosage should be started at 50 mg/kg/day and be increased slowly to a maximum of 30 ml. /day. Levocar 330 mg oral solution can be given from 2-spoonful to 6-spoonful in divided dose as directed by physicians. Higher doses should be administered with caution. Note: Levocar 330 mg 100 ml solution may be consumed alone or dissolved in drink or other liquid food. Doses should be spaced evenly throughout the day preferably during or following meals and should be consumed slowly in order to maximize tolerance.

Interaction of Levocar 330 mg

Reports of INR increase with the use of warfarin have been observed. It is recommended that INR levels be monitored in patients on warfarin therapy after the initiation of treatment with Levocar 330 mg or after dose adjustments.

Contraindications

There is no known disease or syndrome in which Levocar 330 mg administration is contraindicated. It is contraindicated in patients with hypersensitivity to any of its components.

Side Effects of Levocar 330 mg

Generally, Levocar 330 mg is well tolerated. However, few side effects including transient nausea and vomiting, abdominal cramps, and diarrhoea may occur.

Pregnancy & Lactation

Levocar 330 mg is categorized by the USFDA as Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. Supplemental Levocar 330 mg should be used by pregnant women only if clearly indicated and only under medical supervision. It is not known whether Levocar 330 mg is excreted in human milk. Supplemental Levocar 330 mg is not advised for nursing mothers. Those with seizure disorders should only use Levocar 330 mg under medical advisement and supervision.

Precautions & Warnings

Gastrointestinal reactions may result from a too rapid consumption of Levocar 330 mg. The safety and efficacy of oral Levocar 330 mg has not been evaluated in patients with renal insufficiency. Chronic administration of high doses of oral Levocar 330 mg in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine (TMA) and trimethylamine-N oxide (TMAO), since these metabolites are normally excreted in the urine.

Overdose Effects of Levocar 330 mg

There have been no reports of toxicity from Levocar 330 mg overdosage.

Storage Conditions

Do not store above 30°C. Keep away from light and out of the reach of children.

Drug Classes

Drugs for muscular energy metabolism

Mode Of Action

Levocar 330 mg is a naturally occurring substance required in mammalian energy metabolism. It has been shown to facilitate long-chain fatty acid entry into cellular mitochondria, thereby delivering substrate for oxidation and subsequent energy production. Fatty acids are utilized as an energy substrate in all tissues except the brain. In skeletal and cardiac muscle, fatty acids are the main substrate for energy production.

Pregnancy

There is no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Levocar 330 mg supplementation in nursing mothers has not been specifically studied. In nursing mothers receiving Levocar 330 mg, any risks to the child of excess carnitine intake need to be weighed against the benefits of Levocar 330 mg supplementation to the mother. Consideration may be given to discontinuation of nursing or of Levocar 330 mg treatment.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.