Generic medicine

Dexamethasone + Tobramycin: Brands, Price & Uses in Bangladesh

Dexamethasone + Tobramycin is a combination ophthalmic corticosteroid-antibiotic product indicated for: Established/FDA-approved use: Steroid-responsive inflammatory conditions of the eye (e.g.

About Dexamethasone + Tobramycin

Indications of Dexamethasone + Tobramycin

Dexamethasone + Tobramycin is a combination ophthalmic corticosteroid-antibiotic product indicated for:

  • Established/FDA-approved use: Steroid-responsive inflammatory conditions of the eye (e.g. allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected inflammatory conditions of the anterior segment of the globe) for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.
  • Guideline/clinical-practice supported use: Chronic anterior uveitis, and inflammation following ocular surgery, chemical or thermal burns, or removal of a corneal foreign body, when a bacterial infection risk is also present.

Dexamethasone + Tobramycin is intended for short-term, physician-supervised topical ophthalmic use only. It is not indicated for infections without an inflammatory component, and it is not a substitute for an antibiotic alone when no steroid-responsive inflammation is present.

Dosage & Administration of Dexamethasone + Tobramycin

Eye Drops (Suspension)

Shake well before use. Instill 1-2 drops into the conjunctival sac of the affected eye(s) every 4-6 hours. During the initial 24-48 hours of an acute condition, the dosing frequency may be increased to every 2 hours as directed by a physician, then tapered gradually as clinical improvement occurs.

Eye Ointment

Apply a small (approximately 1-1.5 cm) ribbon into the conjunctival sac of the affected eye(s) 3-4 times daily. The ointment may also be used at night as an adjunct to daytime drop therapy. Keep the eyes closed for 1-2 minutes after application.

General Administration Notes

  • Dexamethasone + Tobramycin is for topical ophthalmic use only - not for injection, oral use, or use in the ear.
  • Wash hands before use; avoid touching the applicator tip to the eye or any surface.
  • If using another topical ophthalmic medicine, allow an interval of at least 5-10 minutes between applications.
  • Do not wear contact lenses during treatment of an active ocular infection.
  • Take/use exactly as prescribed by your physician; do not stop, extend, skip doses, or share this medicine with others without medical advice.
  • Duration of use should not exceed what the prescribing physician recommends (see Duration of Treatment).

Side Effects of Dexamethasone + Tobramycin

Adverse effects reported with Dexamethasone + Tobramycin include:

  • Common (local): Transient stinging or burning on instillation, eyelid itching, eyelid swelling, conjunctival hyperemia (redness), and blurred vision immediately after application.
  • Steroid-related (with prolonged use): Elevated intraocular pressure/glaucoma, posterior subcapsular cataract formation, delayed wound/epithelial healing, and secondary ocular infection (bacterial, viral, or fungal) due to masking or potentiation of infection.
  • Hypersensitivity reactions: Localized allergic reactions including lid itching, swelling, and conjunctival erythema (reported in a small proportion of patients).
  • Uncommon: Mydriasis, ptosis, and optic nerve damage with long-term steroid exposure.

Report any unusual or persistent eye symptoms to a physician promptly.

Contraindications of Dexamethasone + Tobramycin

Dexamethasone + Tobramycin is contraindicated in:

  • Most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella.
  • Mycobacterial infection of the eye.
  • Fungal diseases of ocular structures.
  • Known hypersensitivity to tobramycin, dexamethasone, other aminoglycosides, or any component of the formulation.

Frequently Asked Questions about Dexamethasone + Tobramycin

What is Dexamethasone + Tobramycin used for?

Dexamethasone + Tobramycin is used to treat steroid-responsive inflammatory conditions of the eye when there is also a superficial bacterial infection or a risk of one, such as certain cases of allergic conjunctivitis, uveitis, or inflammation following eye injury or surgery.

How should I use Dexamethasone + Tobramycin eye drops?

Shake the bottle well, then instill 1-2 drops of Dexamethasone + Tobramycin into the affected eye every 4-6 hours, or as directed by your physician. During the first 24-48 hours of severe inflammation, your doctor may instruct you to use it as often as every 2 hours before gradually reducing the frequency.

Can I use Dexamethasone + Tobramycin for more than 10 days?

Dexamethasone + Tobramycin should only be used for as long as your physician prescribes. Because prolonged use (beyond 10 days) can raise eye pressure and increase the risk of glaucoma and cataracts, your doctor may want to check your intraocular pressure if treatment continues beyond this period.

Is Dexamethasone + Tobramycin safe during pregnancy or breastfeeding?

There are no adequate studies of Dexamethasone + Tobramycin in pregnant or breastfeeding women. It should be used during pregnancy only if the potential benefit clearly justifies the potential risk to the fetus, and nursing mothers should consult their physician before use, as it is not known whether it passes into breast milk in detectable amounts.

What are the main side effects of Dexamethasone + Tobramycin?

Common side effects of Dexamethasone + Tobramycin include temporary stinging, burning, itching, eyelid swelling, and redness. With prolonged use, corticosteroid-related effects such as increased eye pressure, glaucoma, and cataract formation can occur, so regular follow-up is important.

Who should not use Dexamethasone + Tobramycin?

Dexamethasone + Tobramycin should not be used by people with viral eye infections such as herpes simplex keratitis, vaccinia, or varicella, mycobacterial or fungal eye infections, or those with known hypersensitivity to tobramycin, dexamethasone, or other aminoglycoside antibiotics.

Disclaimer

The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.

DoctorBlogArticles