Generic medicine

Dexketoprofen: Brands, Price & Uses in Bangladesh

Dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the symptomatic relief of mild-to-moderate acute pain.

Forms:Tablet

About Dexketoprofen

Indications of Dexketoprofen

Dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the symptomatic relief of mild-to-moderate acute pain. Its use should be limited to short-term treatment.

Established/Approved Uses

  • Musculoskeletal pain (e.g., muscle strains, sprains, low back pain)
  • Primary dysmenorrhea (menstrual pain)
  • Dental pain (e.g., post-extraction pain)
  • Post-operative pain (injectable formulation, in hospital settings, usually as part of a multimodal analgesia regimen)

Other Uses (Guideline-Supported/Limited Availability)

  • Renal colic (adjunct, injectable formulation, in some countries)

Dexketoprofen is not approved by the US FDA and is not intended for long-term or chronic pain management; it treats the symptom of pain and does not address the underlying cause.

Dosage & Administration of Dexketoprofen

Dexketoprofen should be used at the lowest effective dose for the shortest duration necessary to control symptoms.

Indication/PopulationDoseNotes
Adults - general acute pain (oral)12.5 mg every 4-6 hours or 25 mg every 8 hoursMaximum 75 mg per day
Adults - post-operative/acute pain (injection, hospital use)50 mg by slow IV or deep IM injection, repeated every 8-12 hours as neededMaximum 150 mg per day; short-term hospital use only, generally not exceeding 2 days
ElderlyStart with the lower end of the adult dose (e.g., 50 mg/day oral)Increase cautiously; monitor renal function
Mild-to-moderate renal or hepatic impairmentReduced dose (e.g., maximum 50 mg/day)Use with caution; contraindicated in severe impairment (see Contraindications)
Children/adolescentsNot recommendedSafety and efficacy not established (see Use in Special Populations)

Oral tablets should be swallowed with a glass of water, preferably before meals for faster pain relief, though they may be taken with food if stomach upset occurs. The injectable form of Dexketoprofen is for administration by a healthcare professional only.

Side Effects of Dexketoprofen

Common

  • Nausea, vomiting
  • Abdominal pain, dyspepsia, diarrhea
  • Headache, dizziness
  • Somnolence

Uncommon

  • Insomnia, anxiety
  • Palpitations, flushing
  • Dry mouth
  • Elevated liver enzymes
  • Pruritus, rash
  • Fatigue

Rare/Serious

  • Gastrointestinal ulceration, bleeding, or perforation
  • Cardiovascular thrombotic events (myocardial infarction, stroke) - see Precautions and Warnings
  • Severe hypersensitivity reactions, including anaphylaxis and angioedema
  • Serious skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) - rare
  • Acute renal failure, hepatitis
  • Bronchospasm in susceptible (aspirin/NSAID-sensitive) patients

Patients should seek prompt medical attention for signs of a severe allergic reaction, black or bloody stools, unexplained bruising/bleeding, or yellowing of the skin or eyes.

Contraindications of Dexketoprofen

  • Known hypersensitivity to Dexketoprofen, ketoprofen, or any component of the formulation
  • History of bronchospasm, asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs
  • Active or history of recurrent peptic ulcer, perforation, or gastrointestinal bleeding
  • Active gastrointestinal bleeding, cerebrovascular bleeding, or other active bleeding disorders
  • Severe heart failure
  • Severe renal impairment
  • Severe hepatic impairment
  • Severe dehydration (from vomiting, diarrhea, or insufficient fluid intake)
  • Third trimester of pregnancy
  • Breastfeeding

See Precautions and Warnings for additional cautions that do not amount to absolute contraindications.

Frequently Asked Questions about Dexketoprofen

What is Dexketoprofen used for?

Dexketoprofen is used for the short-term relief of mild-to-moderate acute pain, such as muscle pain, menstrual pain (dysmenorrhea), and dental pain.

How long can I take Dexketoprofen?

Dexketoprofen should be used at the lowest effective dose for the shortest time needed, generally not more than 5 days for oral use, unless your physician directs otherwise. It is not intended for long-term or chronic pain treatment.

Can I take Dexketoprofen if I am pregnant?

Dexketoprofen is contraindicated in the third trimester of pregnancy due to risks to the unborn baby, including premature closure of a fetal heart vessel and reduced amniotic fluid. It is not recommended earlier in pregnancy unless clearly necessary and only under medical supervision, since NSAIDs may increase the risk of miscarriage or fetal complications.

Can I take Dexketoprofen while breastfeeding?

Use of Dexketoprofen while breastfeeding is not recommended, as it is not known with certainty whether it passes into breast milk in amounts that could harm a nursing infant. Please consult your physician for a safer alternative.

What should I avoid while taking Dexketoprofen?

Avoid taking other NSAIDs or aspirin at the same time as Dexketoprofen unless your physician tells you to, as this increases the risk of stomach bleeding and kidney problems. Also avoid alcohol, and inform your doctor about any blood thinners, steroids, or diuretics you are taking.

What should I do if I take too much Dexketoprofen?

If you suspect an overdose of Dexketoprofen, seek immediate medical attention or contact emergency services/poison control right away, even if you feel well, as symptoms of overdose can include stomach bleeding, kidney problems, or breathing difficulty.

Disclaimer

The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.

DoctorBlogArticles