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Empagliflozin: Brands, Price & Uses in Bangladesh
Established Indication - Type 2 Diabetes (Glycemic Control) Empagliflozin is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years…
About Empagliflozin
Indications of Empagliflozin
Established Indication - Type 2 Diabetes (Glycemic Control)
Empagliflozin is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus.
Established Indication - Cardiovascular Risk Reduction
Empagliflozin is indicated to reduce the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovascular disease.
Established Indication - Heart Failure
Empagliflozin is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in adults, regardless of ejection fraction and regardless of the presence of type 2 diabetes.
Established Indication - Chronic Kidney Disease (CKD)
Empagliflozin is indicated to reduce the risk of sustained decline in eGFR, end-stage kidney disease, cardiovascular death, and hospitalization in adults with chronic kidney disease at risk of progression.
Not an Approved Use
Empagliflozin is not approved for use in type 1 diabetes mellitus and is not recommended for the treatment of type 1 diabetes or diabetic ketoacidosis.
Dosage & Administration of Empagliflozin
The dosage of Empagliflozin is determined by a healthcare professional based on the specific indication, renal function, and individual patient response; it is not the same for every patient or every condition. The following table is a general guide and must be confirmed by a physician before use.
Side Effects of Empagliflozin
Common Side Effects
Urinary tract infection, female genital mycotic (yeast) infection, male genital mycotic infection, increased urination, thirst, and nasopharyngitis (common cold-like symptoms).
Serious Side Effects (Seek Medical Attention)
Diabetic ketoacidosis (see Precautions and Warnings for full details), signs of Fournier's gangrene such as severe genital or perineal pain, swelling, redness, or fever (see Precautions and Warnings), symptoms of dehydration or low blood pressure such as dizziness or fainting, signs of kidney problems, hypoglycemia (especially when used with insulin or sulfonylureas), urosepsis or pyelonephritis (serious urinary tract infection with fever, back pain, or vomiting), and hypersensitivity reactions such as angioedema (swelling of the face, lips, tongue, or throat, or difficulty breathing). Seek immediate medical attention if any of these occur.
Contraindications of Empagliflozin
- Known hypersensitivity to Empagliflozin or any component of the formulation, including reactions such as angioedema.
- Severe renal impairment, end-stage renal disease, or patients on dialysis, in whom Empagliflozin is not effective and should not be used.
Frequently Asked Questions about Empagliflozin
What is Empagliflozin used for?
Empagliflozin is used to improve blood sugar control in adults and children aged 10 years and older with type 2 diabetes, and in adults, Empagliflozin is also used to reduce the risk of cardiovascular death and heart failure hospitalization, and to slow progression of certain chronic kidney disease.
How should I take Empagliflozin?
Empagliflozin is usually taken by mouth once daily in the morning, with or without food, exactly as prescribed by your healthcare professional.
What is the usual dose of Empagliflozin?
The typical starting dose of Empagliflozin is 10 mg once daily; for glycemic control, some patients may be increased to 25 mg once daily, but the exact dose of Empagliflozin should always be determined by a doctor based on the indication and kidney function.
Can Empagliflozin be taken with insulin or other diabetes medicines?
Yes, Empagliflozin can be combined with insulin or sulfonylureas, but this combination increases the risk of hypoglycemia (low blood sugar), so a dose adjustment of the other medicine may be needed under medical supervision.
Is Empagliflozin safe during pregnancy or breastfeeding?
Empagliflozin is generally not recommended during pregnancy, particularly in the second and third trimesters, and is not recommended while breastfeeding; a doctor should be consulted to discuss safer alternatives.
Can children take Empagliflozin?
Empagliflozin is approved for glycemic control only in children aged 10 years and older with type 2 diabetes; it has not been established as safe or effective for younger children or for other indications in children.
What are the serious risks of Empagliflozin I should know about?
Empagliflozin carries a risk of diabetic ketoacidosis (which can occur even with near-normal blood sugar), genital yeast infections, and rare but serious Fournier's gangrene; patients should seek urgent medical care for unusual abdominal pain, nausea, vomiting, or genital/perineal pain, swelling, or fever while taking Empagliflozin.
What are the common side effects of Empagliflozin?
Common side effects of Empagliflozin include urinary tract infections, genital yeast infections, increased urination, and increased thirst.
Can I stop taking Empagliflozin suddenly, such as before surgery?
Empagliflozin should not be stopped without medical advice, but your doctor may recommend temporarily stopping Empagliflozin before scheduled surgery or during serious illness to reduce the risk of ketoacidosis; always follow your healthcare professional's specific instructions.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.