10% Off
Polymix G(25 IU+170
Opso Saline Ltd.
৳27.09
Out Of Stock
Generic medicine
Gramacidin + Neomycin + Polymixin B: Brands, Price & Uses in Bangladesh
Gramacidin + Neomycin + Polymixin B is a fixed-dose topical antibiotic combination used for the prevention and treatment of superficial bacterial infections caused by susceptible organisms.
About Gramacidin + Neomycin + Polymixin B
Indications of Gramacidin + Neomycin + Polymixin B
Gramacidin + Neomycin + Polymixin B is a fixed-dose topical antibiotic combination used for the prevention and treatment of superficial bacterial infections caused by susceptible organisms. Its use is classified by strength of evidence below:
Established / Approved Uses
- Superficial bacterial infections of the eye and its adnexa, including bacterial conjunctivitis, blepharitis, and blepharoconjunctivitis, caused by susceptible gram-positive and gram-negative organisms.
- Superficial bacterial infections of the external ear canal (otitis externa) due to susceptible bacteria, where the tympanic membrane is intact.
Adjunct / Prophylactic Use
- Prophylaxis against bacterial infection following minor corneal abrasion or foreign body removal, and after certain minor ophthalmic procedures, as advised by an eye specialist.
Gramacidin + Neomycin + Polymixin B is not effective against viral, fungal, or mycobacterial infections and should not be used for these conditions.
Dosage & Administration of Gramacidin + Neomycin + Polymixin B
Ophthalmic Use (Bacterial Conjunctivitis / Blepharitis)
| Population | Dose |
|---|---|
| Adults | Instill 1–2 drops into the affected eye(s) every 3–4 hours, or more frequently in severe infections, for up to 7–10 days as directed by a physician. |
| Children | Same dosing regimen as adults for topical ophthalmic use, under medical supervision; safety and efficacy in neonates have not been established. |
Otic Use (Bacterial Otitis Externa, Intact Eardrum)
Instill 3–4 drops into the affected ear 3–4 times daily for 7–10 days, or as directed by a physician. Do not use if the eardrum is perforated unless specifically directed by a physician.
General Administration Notes
- Wash hands before use. Avoid touching the applicator tip to the eye, ear, or any surface to prevent contamination.
- Do not exceed the prescribed frequency or duration of treatment.
Antibiotic stewardship: Take Gramacidin + Neomycin + Polymixin B exactly as prescribed by your physician; do not stop, extend, skip doses, or share this medicine with others without medical advice.
Side Effects of Gramacidin + Neomycin + Polymixin B
Most side effects of Gramacidin + Neomycin + Polymixin B are local and mild, but should be reported if persistent or severe:
- Transient burning, stinging, or itching at the site of application.
- Local hypersensitivity or allergic contact dermatitis (notably associated with neomycin).
- Redness, swelling, or irritation of the treated eye or ear.
- Rarely, superinfection with non-susceptible organisms (including fungi) with prolonged use.
- Systemic absorption is minimal with normal topical use, so systemic effects such as ototoxicity or nephrotoxicity are rare but see Precautions and Warnings for conditions that increase this risk.
Contraindications of Gramacidin + Neomycin + Polymixin B
- Known hypersensitivity to gramicidin, neomycin, polymyxin B, or any component of the formulation (neomycin contact sensitization is relatively common).
- Viral infections of the eye or ear (e.g., herpes simplex keratitis, vaccinia, varicella) and fungal infections of ocular or otic structures.
- Otic use in a perforated tympanic membrane is not recommended due to the ototoxic potential of neomycin and polymyxin B, unless specifically directed by a physician who has weighed the risk.
Frequently Asked Questions about Gramacidin + Neomycin + Polymixin B
What is Gramacidin + Neomycin + Polymixin B used for?
Gramacidin + Neomycin + Polymixin B is a topical antibiotic combination used to treat superficial bacterial infections of the eye (such as conjunctivitis) or the outer ear, caused by susceptible bacteria.
How should I use Gramacidin + Neomycin + Polymixin B?
Use exactly as prescribed by your physician — typically 1–2 drops in the affected eye every 3–4 hours, or 3–4 drops in the affected ear 3–4 times daily. Do not stop, extend, skip doses, or share this medicine with others without medical advice.
Can I use Gramacidin + Neomycin + Polymixin B if my eardrum is perforated?
No. Gramacidin + Neomycin + Polymixin B should generally not be used in the ear if the eardrum is perforated, because two of its components can be ototoxic in this situation, unless your physician specifically advises otherwise.
Is Gramacidin + Neomycin + Polymixin B safe during pregnancy or breastfeeding?
Data are limited. Gramacidin + Neomycin + Polymixin B should be used during pregnancy or breastfeeding only if clearly needed and if the potential benefit justifies the potential risk; consult your physician before use.
What side effects can Gramacidin + Neomycin + Polymixin B cause?
Common side effects include mild burning, stinging, itching, or redness at the site of application. Neomycin can occasionally cause allergic skin sensitization. Stop use and consult your physician if irritation worsens.
Can Gramacidin + Neomycin + Polymixin B be used for viral or fungal eye infections?
No. Gramacidin + Neomycin + Polymixin B is only effective against susceptible bacteria and is not indicated for viral (e.g., herpes) or fungal infections of the eye or ear.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.