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Iron Sucrose Injection [Elemental Iron]: Brands, Price & Uses in Bangladesh
Iron Sucrose Injection [Elemental Iron] is a parenteral (intravenous) iron replacement product used to treat iron-deficiency anemia in patients for whom oral iron is inadequate, not tolerated and more.
About Iron Sucrose Injection [Elemental Iron]
Indications of Iron Sucrose Injection [Elemental Iron]
Iron Sucrose Injection [Elemental Iron] is a parenteral (intravenous) iron replacement product used to treat iron-deficiency anemia in patients for whom oral iron is inadequate, not tolerated, or clinically inappropriate.
Established / Guideline-Supported Uses
- Iron-deficiency anemia in chronic kidney disease (CKD): The primary, well-established indication is treatment of iron-deficiency anemia in adult and pediatric patients (2 years and older) with chronic kidney disease, including patients on hemodialysis, peritoneal dialysis, and those who are not yet dialysis-dependent.
Other Guideline-Supported / Adjunct Uses
- Iron-deficiency anemia associated with inflammatory bowel disease (e.g. ulcerative colitis, Crohn's disease) when oral iron is not tolerated or ineffective.
- Correction of iron deficiency in patients with intolerance, malabsorption, or non-compliance with oral iron therapy.
- As an adjunct to erythropoiesis-stimulating agents (ESAs) in CKD-related anemia, where iron replacement supports an adequate response to ESA therapy.
- Selected pre-operative, post-partum, or heavy uterine bleeding-associated iron-deficiency states where rapid iron repletion is clinically indicated, per local (Bangladesh) prescribing practice.
Iron Sucrose Injection [Elemental Iron] is not indicated for anemias not caused by iron deficiency (e.g. hemolytic anemia, anemia of chronic disease without proven iron deficiency).
Dosage & Administration of Iron Sucrose Injection [Elemental Iron]
Iron Sucrose Injection [Elemental Iron] is dosed according to the calculated iron deficit and clinical indication, and is administered only by intravenous injection or infusion by a trained healthcare professional. It must never be given intramuscularly or self-administered by the patient at home.
Adult Dosing (Chronic Kidney Disease-Associated Iron-Deficiency Anemia)
| Population | Typical Dose | Notes |
|---|---|---|
| Hemodialysis-dependent CKD | 100 mg by slow IV injection or infusion | Given repeatedly per dialysis session, per individualized treatment course |
| Non-dialysis-dependent CKD | 200 mg by slow IV injection or infusion | Given on 5 occasions within a 14-day period per treatment course |
| Peritoneal dialysis-dependent CKD | 300 mg then 400 mg by infusion, then 400 mg | Administered over a 28-day treatment course |
Local prescribing practice in Bangladesh commonly describes adult dosing as 100–200 mg elemental iron, given one to three times weekly depending on hemoglobin level and calculated iron deficit, up to a maximum of 200 mg per single injection — this should be individualized by the treating physician based on the calculated total iron deficit.
Pediatric Dosing
In children 2 years of age and older with CKD-associated iron-deficiency anemia, the recommended dose is 0.5 mg/kg by slow IV injection or infusion, repeated as needed, not to exceed 100 mg per dose. Safety and efficacy in children under 2 years have not been established.
Renal/Hepatic Adjustment
No specific dose adjustment beyond the indication-based dosing above is well established for renal or hepatic impairment; Iron Sucrose Injection [Elemental Iron] is in fact the treatment for iron deficiency that commonly accompanies chronic kidney disease, and dosing already accounts for renal status per the schedules above. Use with caution in significant hepatic impairment, with close monitoring for iron overload.
Total cumulative dose should be calculated individually (e.g. using a body-weight/hemoglobin-deficit formula) and should not be exceeded, to avoid iron overload. See Contraindications and Precautions and Warnings.
Side Effects of Iron Sucrose Injection [Elemental Iron]
Adverse effects associated with Iron Sucrose Injection [Elemental Iron] range from common, mild infusion-related symptoms to rare but serious hypersensitivity reactions.
Common
- Hypotension (transient, during or shortly after administration)
- Nausea, vomiting, diarrhea
- Headache, dizziness
- Muscle or leg cramps
- Injection-site reactions (pain, discoloration, swelling)
- Altered/metallic taste
Serious (Uncommon to Rare)
- Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions with hypotension, bronchospasm, loss of consciousness, or collapse — see Precautions and Warnings.
- Significant hypotension requiring monitoring/intervention.
- Arthralgia, myalgia, chest pain (uncommon).
Patients should seek immediate medical attention for symptoms such as difficulty breathing, swelling of the face/throat, rash, or fainting.
Contraindications of Iron Sucrose Injection [Elemental Iron]
Iron Sucrose Injection [Elemental Iron] is contraindicated in patients with:
- Known hypersensitivity to Iron Sucrose Injection [Elemental Iron] or any of its components.
- Evidence of iron overload (e.g. hemochromatosis, hemosiderosis) or disturbances in iron utilization.
Conditions such as active infection or a history of drug allergies are important cautions requiring careful clinical judgment, but are not absolute contraindications — see Precautions and Warnings.
Frequently Asked Questions about Iron Sucrose Injection [Elemental Iron]
What is Iron Sucrose Injection [Elemental Iron] used for?
Iron Sucrose Injection [Elemental Iron] is an intravenous iron replacement medicine used to treat iron-deficiency anemia, most commonly in patients with chronic kidney disease who cannot take or do not adequately respond to oral iron. It may also be used for iron deficiency related to inflammatory bowel disease or other conditions where oral iron is not suitable, as determined by your physician.
Can I give myself Iron Sucrose Injection [Elemental Iron] at home?
No. Iron Sucrose Injection [Elemental Iron] must only be given by a healthcare professional in a hospital or clinic setting equipped to manage allergic reactions, because of the risk of serious hypersensitivity reactions including anaphylaxis. It is not a self-administered, take-home injection.
What are the most serious risks of Iron Sucrose Injection [Elemental Iron]?
The most serious risk is a hypersensitivity reaction, including rare but potentially life-threatening anaphylaxis, which is why Iron Sucrose Injection [Elemental Iron] is given only where resuscitation facilities and trained staff are available, with monitoring during the infusion and for at least 30 minutes afterward. Other risks include a drop in blood pressure (hypotension) during or after the infusion, and iron overload if doses exceed what your body needs — your physician calculates your dose carefully to avoid this.
Is Iron Sucrose Injection [Elemental Iron] safe during pregnancy or breastfeeding?
Iron Sucrose Injection [Elemental Iron] should be used during pregnancy only if clearly needed and if the potential benefit justifies the potential risk to the baby, generally avoided in the first trimester unless essential, and only under a physician's direct supervision. Small amounts may pass into breast milk; breastfeeding mothers should use Iron Sucrose Injection [Elemental Iron] only on their doctor's advice.
Can children receive Iron Sucrose Injection [Elemental Iron]?
Iron Sucrose Injection [Elemental Iron] is approved for children 2 years of age and older with chronic kidney disease-associated iron-deficiency anemia, dosed by body weight (0.5 mg/kg, maximum 100 mg per dose). Safety and efficacy in children younger than 2 years have not been established.
What should I tell my doctor before receiving Iron Sucrose Injection [Elemental Iron]?
Tell your doctor about any known allergies (especially to iron products), any history of severe allergic reactions, whether you have an active infection, liver disease, or existing iron overload, and whether you are pregnant, planning pregnancy, or breastfeeding, as these affect whether and how Iron Sucrose Injection [Elemental Iron] should be used.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.