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Levobunolol: Brands, Price & Uses in Bangladesh
Levobunolol is a non-selective beta-adrenergic blocking agent formulated as an ophthalmic (eye) solution.
About Levobunolol
Indications of Levobunolol
Levobunolol is a non-selective beta-adrenergic blocking agent formulated as an ophthalmic (eye) solution. It is FDA-approved for the following uses:
- Chronic open-angle glaucoma: Established use of Levobunolol for lowering elevated intraocular pressure (IOP).
- Ocular hypertension: Established use of Levobunolol for reducing elevated IOP in patients without glaucomatous field loss, to reduce the risk of progression to glaucoma.
Levobunolol may also be used as adjunctive therapy in combination with other IOP-lowering agents (for example, prostaglandin analogues or carbonic anhydrase inhibitors) when a single agent does not adequately control intraocular pressure. Levobunolol is not indicated as monotherapy for acute angle-closure glaucoma and is not an antibiotic or anti-infective agent.
Dosage & Administration of Levobunolol
| Indication | Dose |
|---|---|
| Chronic open-angle glaucoma / ocular hypertension (adults) | One drop of Levobunolol 0.5% solution in the affected eye(s) once daily; some patients may require one drop twice daily if IOP is not adequately controlled with once-daily dosing. |
| Lower-strength formulation | One drop of Levobunolol 0.25% solution in the affected eye(s) once or twice daily, as directed by the physician. |
Use Levobunolol exactly as directed by the prescribing physician. If more than one topical ophthalmic medication is being used, administer them at least 5 minutes apart. For instillation technique, see Administration below.
Side Effects of Levobunolol
The most common effect of Levobunolol is transient ocular burning and stinging upon instillation (reported in up to about 1 in 3 patients), and blepharoconjunctivitis (in up to about 1 in 20 patients).
Less common effects reported with Levobunolol include:
- Ocular: iridocyclitis, decreased corneal sensitivity, conjunctival hyperemia, blurred vision
- Cardiovascular: bradycardia, hypotension, syncope, heart block (see Contraindications and Precautions)
- Respiratory: bronchospasm, dyspnea (see Contraindications)
- Systemic/other: headache, dizziness, transient ataxia, lethargy, urticaria, pruritus, depression, confusion, muscle weakness
Contraindications of Levobunolol
Levobunolol is contraindicated in patients with:
- Bronchial asthma or a history of bronchial asthma
- Severe chronic obstructive pulmonary disease
- Sinus bradycardia
- Second- or third-degree atrioventricular block
- Overt cardiac failure or cardiogenic shock
- Known hypersensitivity to Levobunolol or any component of the formulation
Frequently Asked Questions about Levobunolol
What is Levobunolol used for?
Levobunolol is an ophthalmic beta-blocker eye drop used to lower elevated intraocular pressure in patients with chronic open-angle glaucoma or ocular hypertension.
How should I use Levobunolol eye drops?
Instill the prescribed number of drops of Levobunolol into the affected eye(s), usually once daily, exactly as directed by your physician. Wash your hands first and avoid touching the dropper tip to your eye or any surface.
Who should not use Levobunolol?
Levobunolol should not be used by people with bronchial asthma or a history of asthma, severe COPD, sinus bradycardia, second- or third-degree heart block, overt heart failure, cardiogenic shock, or known hypersensitivity to Levobunolol or its ingredients.
Can Levobunolol be used during pregnancy or breastfeeding?
Levobunolol should be used during pregnancy only if the potential benefit clearly justifies the potential risk to the fetus, and with caution during breastfeeding, since systemic beta-blockers can pass into breast milk. Always consult your physician before using Levobunolol if you are pregnant or breastfeeding.
What side effects can Levobunolol cause?
The most common side effects of Levobunolol are transient burning or stinging in the eye and inflammation of the eyelid or conjunctiva. Less commonly, Levobunolol can be absorbed into the bloodstream and cause systemic effects such as a slow heart rate, low blood pressure, or breathing difficulty.
What should I do if I miss a dose or suspect an overdose of Levobunolol?
If you miss a dose, apply Levobunolol as soon as you remember, unless it is almost time for your next dose, in which case skip the missed dose. If you suspect an overdose of Levobunolol, especially if it was swallowed, seek immediate medical attention or contact a poison control center right away.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.