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Naftol25 mg
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Generic medicine
Naftopidil: Brands, Price & Uses in Bangladesh
Naftopidil is indicated for the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in adult men.
About Naftopidil
Indications of Naftopidil
Naftopidil is indicated for the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in adult men.
- Established/labeled use: Relief of voiding symptoms (weak urinary stream, hesitancy, incomplete bladder emptying) and storage symptoms (urgency, frequency, nocturia) caused by benign prostatic hyperplasia/benign prostatic obstruction.
- Mechanistic rationale for storage symptoms: Because of its relatively selective action on alpha-1D adrenoceptors (concentrated in the bladder and spinal cord) in addition to alpha-1A receptors in the prostate, Naftopidil is particularly useful when overactive-bladder-type storage symptoms accompany BPH.
Naftopidil does not reduce prostate size and is not a treatment for prostate cancer; it treats urinary symptoms only.
Not indicated for use in women or in children, since benign prostatic hyperplasia is a condition specific to the male prostate gland.
Dosage & Administration of Naftopidil
Adult Dose (Benign Prostatic Hyperplasia / LUTS)
| Step | Dose | Timing |
|---|---|---|
| Starting dose | 25 mg once daily | After a meal |
| Titration | Increase to 50 mg, then up to a maximum of 75 mg once daily as needed, at intervals of 1-2 weeks | After a meal |
| Maximum dose | 75 mg once daily | After a meal |
Tablets should be swallowed whole with water. Naftopidil is intended for long-term, individualized use guided by symptom response (see Duration of Treatment).
Renal and Hepatic Impairment
- Renal impairment: No dose adjustment is generally required.
- Hepatic impairment: Use with caution and consider a lower starting dose in mild-to-moderate impairment; Naftopidil is contraindicated in severe hepatic impairment (see Contraindications).
Pediatric Use
Naftopidil is not indicated in children (see Pediatric Uses).
Side Effects of Naftopidil
The most commonly reported side effects of Naftopidil include:
- Dizziness and lightheadedness
- Headache
- Tiredness/fatigue
- Blurred vision
- Stomach discomfort/gastrointestinal upset
Less commonly, orthostatic (postural) hypotension can occur, particularly after the first dose or a dose increase (see Precautions and Warnings). Report any severe dizziness, fainting, palpitations, or vision changes to your physician promptly.
Contraindications of Naftopidil
Naftopidil is contraindicated in:
- Known hypersensitivity to Naftopidil or any component of the formulation.
- Severe hepatic impairment.
Naftopidil is not intended for use in women, as benign prostatic hyperplasia is a male-specific condition.
Frequently Asked Questions about Naftopidil
What is Naftopidil used for?
Naftopidil is used to relieve the urinary symptoms of benign prostatic hyperplasia (BPH) in adult men, including difficulty urinating, weak stream, urgency, frequency, and nighttime urination. It does not shrink the prostate or treat prostate cancer.
How should I take Naftopidil?
Naftopidil is usually started at 25 mg once daily after a meal and may be increased by your doctor to 50 mg or up to a maximum of 75 mg once daily, based on your response. Take it at the same time each day and swallow the tablet whole with water.
Can women or children take Naftopidil?
No. Naftopidil is approved only for adult men with BPH, a condition specific to the male prostate gland. It is not indicated for use in women or children.
What are the main side effects of Naftopidil?
The most common side effects of Naftopidil are dizziness, headache, tiredness, blurred vision, and stomach discomfort. Some people may experience a drop in blood pressure on standing, especially after the first dose or a dose increase.
Is it safe to have cataract surgery while taking Naftopidil?
Patients currently or previously taking Naftopidil or similar alpha-1 blockers are at risk of intraoperative floppy iris syndrome (IFIS) during cataract surgery. Always inform your ophthalmologist that you are taking or have taken Naftopidil before any eye surgery.
What should I do if I miss a dose or take too much Naftopidil?
If you miss a dose of Naftopidil, take it as soon as you remember unless it is near the time for your next dose - do not double the dose. If you suspect an overdose, which can cause severe dizziness or fainting from low blood pressure, seek immediate medical attention or contact a poison control center.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.