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Naproxen Sodium: Brands, Price & Uses in Bangladesh
Naproxen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce fever, and control inflammation.
About Naproxen Sodium
Indications of Naproxen Sodium
Naproxen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce fever, and control inflammation. Indications are classified below by strength of evidence.
Established / FDA-approved uses
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Juvenile idiopathic arthritis (pediatric, weight-based dosing)
- Acute painful shoulder (bursitis/tendinitis)
- Acute gouty arthritis
- Primary dysmenorrhea
- Mild-to-moderate acute pain (musculoskeletal injury, postoperative pain, headache/migraine)
Guideline-supported / commonly used uses
- Fever reduction (antipyretic use)
- Tension-type headache and acute migraine attack (often as adjunct or when first-line agents are insufficient)
Naproxen Sodium is not an antibiotic and has no role in treating infections.
Dosage & Administration of Naproxen Sodium
Adult dosing of Naproxen Sodium by indication
| Indication | Typical adult dose |
|---|---|
| Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis | 275-550 mg twice daily; maintenance up to 1,100 mg/day in divided doses if needed |
| Acute musculoskeletal pain, mild-to-moderate pain, primary dysmenorrhea | 550 mg initially, then 275 mg every 6-8 hours or 550 mg every 12 hours; total not to exceed 1,375 mg on the first day, then 1,100 mg/day thereafter |
| Acute gout | 825 mg initially, then 275 mg every 8 hours until the attack subsides |
| Juvenile idiopathic arthritis (pediatric) | Approximately 10 mg/kg/day naproxen equivalent in two divided doses (using the oral suspension); tablets are generally not suitable for children weighing under 50 kg |
The lowest effective dose should be used for the shortest duration consistent with the treatment goal, because of cardiovascular and gastrointestinal risks (see Precautions and Warnings). Renal or hepatic impairment: use the lowest effective dose and monitor closely; avoid in severe impairment (see Use in Special Populations).
Side Effects of Naproxen Sodium
Common side effects of Naproxen Sodium include dyspepsia, heartburn, abdominal pain, nausea, constipation or diarrhea, headache, dizziness, drowsiness, tinnitus, and fluid retention/edema.
Serious but less common effects include gastrointestinal bleeding/ulceration/perforation, cardiovascular thrombotic events (myocardial infarction, stroke), renal impairment, elevated liver enzymes/hepatotoxicity, hypertension, hyperkalemia, aseptic meningitis, and severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) or anaphylactoid reactions. Seek urgent medical care for signs such as black/bloody stools, chest pain, sudden weakness, jaundice, or severe rash.
Contraindications of Naproxen Sodium
Naproxen Sodium is contraindicated in:
- Known hypersensitivity to naproxen or any component of the formulation.
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs (cross-reactivity risk).
- Active gastrointestinal bleeding or active peptic ulcer disease.
- Use in the setting of coronary artery bypass graft (CABG) surgery, including for perioperative pain.
- Severe, uncontrolled heart failure.
- Third trimester of pregnancy (see Pregnancy and Lactation).
Frequently Asked Questions about Naproxen Sodium
What is Naproxen Sodium used for?
Naproxen Sodium is an NSAID used to relieve pain, fever, and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, muscle/joint injuries, menstrual cramps (dysmenorrhea), and headache.
How should I take Naproxen Sodium?
Take Naproxen Sodium tablets whole with a full glass of water, preferably with food or milk to reduce stomach upset, exactly as directed by your physician. Do not crush or chew sustained-release tablets, and do not exceed the recommended dose or duration.
Can I take Naproxen Sodium during pregnancy?
Naproxen Sodium should be avoided from about 20 weeks of pregnancy onward, and is contraindicated in the third trimester (about 30 weeks and later) because it can cause serious harm to the baby, including premature closure of a fetal blood vessel. Earlier in pregnancy, use only if your physician determines it is clearly needed, at the lowest dose for the shortest time.
Is Naproxen Sodium safe while breastfeeding?
Small amounts of naproxen pass into breast milk. Naproxen Sodium should be used during breastfeeding only if your physician judges the benefit outweighs the potential risk to the infant.
What are the serious side effects of Naproxen Sodium I should watch for?
Stop Naproxen Sodium and seek urgent medical attention if you notice black or bloody stools, vomiting blood, severe stomach pain, chest pain, sudden weakness or slurred speech, unusual swelling, yellowing of the skin/eyes, or a severe skin rash, as these can signal serious gastrointestinal, cardiovascular, hepatic, or allergic reactions.
What should I do if I take too much Naproxen Sodium?
An overdose of Naproxen Sodium is a medical emergency. Seek immediate medical attention or contact emergency services/poison control right away; do not try to treat an overdose at home.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.