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Prednisolone Acetate: Brands, Price & Uses in Bangladesh

Prednisolone Acetate ophthalmic suspension is a corticosteroid indicated for the treatment of steroid-responsive inflammatory conditions of the eye.

Forms:Ophthalmic Suspension

About Prednisolone Acetate

Indications of Prednisolone Acetate

Prednisolone Acetate ophthalmic suspension is a corticosteroid indicated for the treatment of steroid-responsive inflammatory conditions of the eye. Its established and guideline-supported uses include:

  • Established/approved use: Steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe, such as allergic conjunctivitis, acne rosacea (ocular), superficial punctate keratitis, herpes zoster keratitis (non-dendritic), iritis, and cyclitis.
  • Established/approved use: Selected infective conjunctivitis, when the inherent hazard of steroid use is accepted and an anti-infective agent is co-administered to control the infection.
  • Established/approved use: Reduction of inflammation and edema following ocular injury from chemical, radiation, or thermal burns, or penetration of foreign bodies.
  • Established/approved use: Management of post-operative inflammation following ophthalmic surgery (e.g. cataract surgery).

Prednisolone Acetate is not indicated for use in undiagnosed "red eye" without prior ophthalmologic evaluation, since it may mask or worsen an underlying infection.

Dosage & Administration of Prednisolone Acetate

General Dosing

Indication / SeverityRecommended Dosage of Prednisolone Acetate
Mild to moderate ocular inflammationInstill 1–2 drops into the conjunctival sac 2 to 4 times daily.
Severe ocular inflammation (initial 24–48 hours)Instill 1–2 drops every 1 to 2 hours while awake, then reduce frequency gradually as inflammation subsides.
Post-operative inflammationAs directed by the ophthalmologist, typically 2 to 4 times daily, tapered over 1–2 weeks.

Shake the bottle well before each use, as Prednisolone Acetate is a suspension. Treatment should not be discontinued prematurely; the dose should be tapered gradually under medical supervision, as abrupt discontinuation may cause rebound inflammation.

If used together with an anti-infective agent for infective conjunctivitis, both medicines should be used exactly as prescribed. See Precautions and Warnings for monitoring requirements during prolonged use.

Side Effects of Prednisolone Acetate

Side effects associated with Prednisolone Acetate ophthalmic suspension are usually local to the eye and include:

  • Transient stinging, burning, or blurred vision immediately after instillation.
  • Elevated intraocular pressure (IOP) / steroid-induced glaucoma with prolonged use, which may lead to optic nerve damage and visual field defects.
  • Posterior subcapsular cataract formation with long-term use.
  • Delayed corneal or scleral wound healing.
  • Secondary ocular infection (bacterial, viral, or fungal) due to suppression of the host inflammatory response, or perforation of the globe where thinning of the cornea or sclera exists.
  • Mydriasis (pupil dilation) and ptosis (drooping eyelid) have been reported infrequently.

Patients should promptly report eye pain, significant vision changes, or persistent redness to their physician.

Contraindications of Prednisolone Acetate

Prednisolone Acetate ophthalmic suspension is contraindicated in:

  • Acute, untreated bacterial infections of the eye.
  • Acute, untreated fungal diseases of ocular structures.
  • Most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella.
  • Mycobacterial infection of the eye.
  • Known hypersensitivity to prednisolone acetate or any component of the formulation.

Frequently Asked Questions about Prednisolone Acetate

What is Prednisolone Acetate eye drop used for?

Prednisolone Acetate ophthalmic suspension is used to treat steroid-responsive inflammation of the eye, such as allergic conjunctivitis, iritis, cyclitis, and inflammation following eye surgery or injury. It should only be used under a physician's or ophthalmologist's guidance.

How should I use Prednisolone Acetate eye drops correctly?

Shake the bottle well, wash your hands, tilt your head back, and instill the prescribed number of drops of Prednisolone Acetate into the lower eyelid pocket without touching the dropper tip to your eye. Close your eyes gently for 1–2 minutes afterward. Use exactly as prescribed, usually 2 to 4 times daily.

Can Prednisolone Acetate be used for a red or infected eye without seeing a doctor?

No. Prednisolone Acetate should not be used for undiagnosed red eye, because corticosteroids can mask or worsen an underlying bacterial, viral, or fungal eye infection. Always have a red or painful eye evaluated by a physician before starting Prednisolone Acetate.

What are the main risks of using Prednisolone Acetate for a long time?

Prolonged use of Prednisolone Acetate can raise intraocular pressure and lead to glaucoma, cause cataracts, delay wound healing, and increase the risk of secondary eye infections. Regular eye pressure checks are recommended if treatment continues beyond 10 days.

Is Prednisolone Acetate safe to use during pregnancy or breastfeeding?

Prednisolone Acetate should be used during pregnancy or breastfeeding only if clearly needed and if a physician determines the benefit outweighs any potential risk. Please consult your doctor before using Prednisolone Acetate if you are pregnant, planning pregnancy, or breastfeeding.

What should I do if I accidentally use too much Prednisolone Acetate?

If you instill more Prednisolone Acetate than prescribed or a large amount is accidentally ingested, rinse the eye with clean water if applicable and seek immediate medical attention or contact a poison control center rather than trying to manage it at home.

Disclaimer

The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.

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