10% Off
Poly-Pred(5 mg+3.5
Eskayef Bangladesh Ltd.
৳201.37
Add to cart
Generic medicine
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate: Brands, Price & Uses in Bangladesh
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate is a topical corticosteroid-antibiotic combination indicated for steroid-responsiveinflammatory conditions of the eye and and more.
About Prednisolone + Neomycin Sulphate + Polymixin B Sulphate
Indications of Prednisolone + Neomycin Sulphate + Polymixin B Sulphate
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate is a topical corticosteroid-antibiotic combination indicated for steroid-responsiveinflammatory conditions of the eye and, in appropriate formulations, the external ear, where superficialbacterial infection or a risk of bacterial infection is present.
Established/labeled uses
- Steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anteriorsegment of the eye, when a bacterial infection or risk of bacterial infection exists (e.g. allergicconjunctivitis, vernal conjunctivitis, episcleritis, anterior uveitis (iritis/cyclitis)).
- Corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies, whereinflammation control and infection prophylaxis are both required.
- Superficial bacterial infections of the external ear canal (otitis externa) accompanied by inflammation,when the tympanic membrane is intact (otic formulations only).
Adjunct / commonly-used-off-label
- As an adjunct after certain ophthalmic surgical procedures to control postoperative inflammation whilecovering susceptible bacteria, under specialist supervision.
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate should be prescribed only after a qualified clinician has examined the eye or ear andexcluded infections for which a corticosteroid would be harmful (see Contraindications).
Dosage & Administration of Prednisolone + Neomycin Sulphate + Polymixin B Sulphate
Ophthalmic use
| Population | Typical dose |
|---|---|
| Adults and children (as directed by physician) | Instill 1-2 drops into the affected eye(s)every 3-4 hours; the physician may direct more frequent dosing (e.g. every 1-2 hours) during the first 24-48hours in severe inflammation, then taper as improvement occurs. |
Otic use (external ear only, intact eardrum)
| Population | Typical dose |
|---|---|
| Adults and children (as directed by physician) | Instill 3-4 drops into the affected ear canal3-4 times daily, or as prescribed. |
Administration notes
- Shake the suspension well before use.
- Wash hands before and after use; avoid touching the applicator tip to the eye, ear, or any surface.
- If using more than one topical eye medicine, space applications at least 5 minutes apart.
- Take/use exactly as prescribed by your physician; do not stop, extend, skip doses, or share this medicinewith others without medical advice.
- Do not use for longer than the physician-directed course; prolonged use increases the risk of ocularcomplications (see Precautions).
Side Effects of Prednisolone + Neomycin Sulphate + Polymixin B Sulphate
Most adverse effects of Prednisolone + Neomycin Sulphate + Polymixin B Sulphate are local and related to the site of application.
Common
- Transient burning, stinging, itching, or a foreign-body sensation at the site of instillation.
- Temporary blurring of vision immediately after ophthalmic use.
Less common but important
- Allergic/hypersensitivity reactions, including contact sensitization to the neomycin component (itching,redness, swelling, worsening irritation).
- With prolonged or repeated use: raised intraocular pressure/glaucoma with possible optic nerve damage,posterior subcapsular cataract formation, delayed wound/epithelial healing, and secondary ocular infection(bacterial or fungal) due to suppression of the local immune response.
- Thinning or perforation of the cornea or sclera in eyes with pre-existing thinning disorders.
Patients should stop the medicine and seek medical advice promptly if irritation, pain, redness, or visionchanges worsen or persist.
Contraindications of Prednisolone + Neomycin Sulphate + Polymixin B Sulphate
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate is contraindicated in:
- Most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis(dendritic keratitis), vaccinia, and varicella, because the corticosteroid component can worsen theseinfections.
- Fungal or mycobacterial (e.g. tuberculous) infections of the eye or ear.
- A perforated tympanic membrane, when an otic formulation is intended, because of the ototoxicity risk ofthe aminoglycoside component reaching the middle/inner ear.
- Known hypersensitivity to prednisolone, neomycin, polymixin B, or any other component of theformulation.
Frequently Asked Questions about Prednisolone + Neomycin Sulphate + Polymixin B Sulphate
What is Prednisolone + Neomycin Sulphate + Polymixin B Sulphate used for?
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate is a combination eye/ear medicine used to treat inflammation of the eye (such as allergic conjunctivitis, uveitis, or inflammation after an eye injury) or bacterial infection of the external ear canal, when a bacterial infection or risk of one is also present.
Can I use this medicine for a red eye without seeing a doctor first?
No. Prednisolone + Neomycin Sulphate + Polymixin B Sulphate should not be used for an undiagnosed red eye without a professional diagnosis, because the corticosteroid component can worsen certain infections, such as viral (herpes) keratitis, fungal, or mycobacterial infections, and can mask the true cause of the redness.
How long can I safely use Prednisolone + Neomycin Sulphate + Polymixin B Sulphate?
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate should be used for the shortest period your physician recommends, usually no more than 7-10 days without follow-up. Prolonged use raises the risk of increased eye pressure, cataract, delayed healing, and secondary infection.
Is it safe to use Prednisolone + Neomycin Sulphate + Polymixin B Sulphate in the ear if my eardrum is perforated?
No. Prednisolone + Neomycin Sulphate + Polymixin B Sulphate should not be instilled into the ear canal if the eardrum is perforated or suspected to be perforated, because the neomycin component can be ototoxic if it reaches the middle or inner ear.
Can Prednisolone + Neomycin Sulphate + Polymixin B Sulphate be used during pregnancy or breastfeeding?
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate should be used during pregnancy or breastfeeding only if clearly needed and if your physician judges that the benefit outweighs the potential risk, since well-controlled human studies are lacking. Always consult your physician first.
What should I do if I notice worsening irritation or vision changes while using this medicine?
Stop using Prednisolone + Neomycin Sulphate + Polymixin B Sulphate and contact your physician promptly if you notice worsening pain, redness, irritation, or any change in vision, as these can be signs of a complication that needs medical assessment.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.