10% Off
Dephos500 mg
Eskayef Bangladesh Ltd.
৳486.00
Out Of Stock
Generic medicine
Sucroferric Oxyhydroxide: Brands, Price & Uses in Bangladesh
Sucroferric Oxyhydroxide is an iron-based, calcium-free phosphate binder with the following approved and guideline-supported uses: Established / FDA-Approved Use Control of serum phosphorus…
About Sucroferric Oxyhydroxide
Indications of Sucroferric Oxyhydroxide
Sucroferric Oxyhydroxide is an iron-based, calcium-free phosphate binder with the following approved and guideline-supported uses:
Established / FDA-Approved Use
- Control of serum phosphorus (hyperphosphatemia) in adults with chronic kidney disease (CKD) who are on dialysis (hemodialysis or peritoneal dialysis), as part of an overall management plan that also includes dietary phosphate restriction.
- Control of serum phosphorus in pediatric patients 9 years of age and older with CKD on dialysis.
Not Established / Not Recommended
- Sucroferric Oxyhydroxide has not been studied and is not recommended for hyperphosphatemia in patients with CKD who are not yet on dialysis.
- Use in children younger than 9 years has not been established.
Sucroferric Oxyhydroxide is intended for chronic, ongoing use alongside routine dialysis care and periodic laboratory monitoring, not as a stand-alone or short-course treatment.
Dosage & Administration of Sucroferric Oxyhydroxide
How to Take
- Sucroferric Oxyhydroxide tablets must be chewed completely or crushed before swallowing — do not swallow tablets whole.
- Take Sucroferric Oxyhydroxide with meals for optimal phosphate-binding effect.
Dosing by Indication
| Population | Starting Dose | Titration |
|---|---|---|
| Adults and children ≥ 12 years on dialysis | One 500 mg tablet three times daily with meals (1500 mg/day) | Adjust by one tablet (500 mg) per day at intervals of one week or longer, based on serum phosphorus levels, up to a maximum studied dose of 3000 mg/day |
| Children 9 to less than 12 years on dialysis | One 500 mg tablet twice daily with meals (1000 mg/day) | Adjust under close physician supervision based on serum phosphorus response |
Dose should be individualized and titrated to achieve and maintain an acceptable serum phosphorus level, with regular monitoring by the treating nephrologist. See Use in Special Populations for pediatric and elderly considerations, and Interactions for dosing-separation advice with other oral medicines.
Side Effects of Sucroferric Oxyhydroxide
The most common side effects of Sucroferric Oxyhydroxide are gastrointestinal and generally mild to moderate:
- Discolored (dark) stool — very common (reported in roughly 1 in 8 patients); this is an expected, harmless cosmetic effect of the iron content and does not indicate gastrointestinal bleeding. New or unusual gastrointestinal symptoms (such as blood in stool, severe abdominal pain, or black tarry stool with other warning signs) should still be evaluated by a physician.
- Diarrhea — common, often improves with continued use or dose adjustment.
- Nausea, vomiting, constipation, and flatulence — reported less frequently.
Uncommon effects reported after marketing include tooth discoloration (typically reversible with dental hygiene) and skin rash. Patients should contact their physician if side effects are severe, persistent, or accompanied by other concerning symptoms.
Contraindications of Sucroferric Oxyhydroxide
Sucroferric Oxyhydroxide is contraindicated in patients with known hypersensitivity to Sucroferric Oxyhydroxide or any component of the formulation. No other absolute contraindications are established. Patients with conditions such as active peritonitis, significant hepatic or gastrointestinal disorders, iron-overload conditions (e.g., hemochromatosis), or recent major gastrointestinal surgery were excluded from clinical trials of Sucroferric Oxyhydroxide and require careful clinical judgment and monitoring rather than automatic exclusion — see Precautions and Warnings.
Frequently Asked Questions about Sucroferric Oxyhydroxide
What is Sucroferric Oxyhydroxide used for?
Sucroferric Oxyhydroxide is used to control high blood phosphorus levels (hyperphosphatemia) in adults and children 9 years of age and older with chronic kidney disease who are on dialysis. It works by binding phosphate from food in the gut so that less of it is absorbed into the blood.
How should I take Sucroferric Oxyhydroxide?
Sucroferric Oxyhydroxide tablets should be chewed completely or crushed — never swallowed whole — and taken with meals, since it needs to be present in the gut together with food to bind dietary phosphate effectively.
Why does Sucroferric Oxyhydroxide turn my stool dark?
Dark or discolored stool is a very common and expected effect of Sucroferric Oxyhydroxide because of its iron content. It is generally harmless and does not mean there is gastrointestinal bleeding. However, if you notice true blood in the stool, black tarry stool with dizziness or weakness, or other new and worrying gastrointestinal symptoms, contact your doctor.
Can Sucroferric Oxyhydroxide be taken with other medications?
Sucroferric Oxyhydroxide can reduce the absorption of some oral medicines, such as levothyroxine, if taken at the same time. Tell your doctor or pharmacist about all medicines you take so they can advise on spacing doses appropriately; do not stop or adjust any other medication on your own.
Is Sucroferric Oxyhydroxide safe during pregnancy or breastfeeding?
Sucroferric Oxyhydroxide is only minimally absorbed into the bloodstream, so significant exposure to a baby is not expected, but data in pregnant and breastfeeding women are limited. Sucroferric Oxyhydroxide should be used in pregnancy only if clearly needed, and any use during pregnancy or breastfeeding should be supervised by your nephrologist.
What should I do if I take too much Sucroferric Oxyhydroxide?
If you or someone else has taken more Sucroferric Oxyhydroxide than prescribed, seek immediate medical attention or contact a poison control center / emergency services right away. Do not try to treat a suspected overdose at home.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.