10% Off
Ticlopid250 mg
Drug International Ltd.
৳6.30
Add to cart
Generic medicine
Ticlopidine Hydrochloride: Brands, Price & Uses in Bangladesh
Ticlopidine Hydrochloride is an antiplatelet medicine belonging to the thienopyridine class.
About Ticlopidine Hydrochloride
Indications of Ticlopidine Hydrochloride
Ticlopidine Hydrochloride is an antiplatelet medicine belonging to the thienopyridine class. Because of its serious hematologic side-effect profile, it is generally reserved for patients who cannot tolerate or have failed other antiplatelet therapies (such as aspirin or clopidogrel).
- Established/FDA-approved use: Reduction of the risk of thrombotic stroke (fatal or non-fatal) in patients who have experienced stroke precursors (e.g., transient ischemic attacks) or who have had a completed thrombotic stroke.
- Established/FDA-approved use (combination therapy): Prevention of subacute stent thrombosis, used in combination with aspirin, following successful coronary artery stent implantation.
Ticlopidine Hydrochloride is typically considered a second-line antiplatelet agent rather than a first-choice therapy, due to the availability of alternatives with a more favorable safety profile.
Dosage & Administration of Ticlopidine Hydrochloride
Dosing of Ticlopidine Hydrochloride should be individualized by a physician based on indication and patient tolerance. Regular blood monitoring is required (see Precautions and Warnings).
| Indication | Adult Dose | Notes |
|---|---|---|
| Reduction of thrombotic stroke risk | 250 mg orally twice daily | Take with food to reduce gastrointestinal upset. |
| Prevention of subacute stent thrombosis | 250 mg orally twice daily, in combination with aspirin | Usually continued for up to approximately 30 days post-stenting, as directed by the treating physician. |
Pediatric dosing has not been established (see Use in Special Populations). No well-established formal renal dose adjustment exists; hepatic impairment requires caution and is contraindicated if severe (see Contraindications).
Side Effects of Ticlopidine Hydrochloride
Common side effects of Ticlopidine Hydrochloride include:
- Diarrhea and gastrointestinal upset (common)
- Nausea, dyspepsia, abdominal pain
- Skin rash
- Elevated blood cholesterol and triglyceride levels
- Bruising or minor bleeding (e.g., nosebleeds, gum bleeding)
Serious but less common effects requiring immediate medical attention include severe neutropenia/agranulocytosis, thrombotic thrombocytopenic purpura (TTP), aplastic anemia, serious bleeding, and liver enzyme abnormalities (see Precautions and Warnings).
Contraindications of Ticlopidine Hydrochloride
- Known hypersensitivity to Ticlopidine Hydrochloride or any component of the formulation.
- Hematopoietic disorders, such as neutropenia or thrombocytopenia.
- Hemostatic disorders or the presence of active pathological bleeding, such as an active peptic ulcer or intracranial hemorrhage.
- Severe hepatic impairment.
Frequently Asked Questions about Ticlopidine Hydrochloride
What is Ticlopidine Hydrochloride used for?
Ticlopidine Hydrochloride is used to reduce the risk of thrombotic stroke in people who have had warning signs of stroke or a prior thrombotic stroke, and, in combination with aspirin, to help prevent blood clots (subacute stent thrombosis) after coronary artery stent placement.
Why is regular blood testing needed while taking Ticlopidine Hydrochloride?
Ticlopidine Hydrochloride can rarely cause serious blood disorders such as neutropenia, thrombotic thrombocytopenic purpura (TTP), and aplastic anemia. Regular complete blood counts, especially during the first three months of treatment, help detect these problems early so treatment can be stopped promptly if needed.
What warning signs should prompt me to stop Ticlopidine Hydrochloride and seek medical help?
Contact your physician immediately and stop Ticlopidine Hydrochloride if you develop fever, sore throat, unusual bruising or bleeding, or other signs of infection, as these may indicate a serious blood disorder.
Can Ticlopidine Hydrochloride be taken during pregnancy or breastfeeding?
Data on the use of Ticlopidine Hydrochloride during pregnancy are limited, so it should be used only if clearly needed and if the benefit outweighs the potential risk to the baby. It is not known whether Ticlopidine Hydrochloride passes into breast milk, so a physician should be consulted before use while breastfeeding.
Can Ticlopidine Hydrochloride be taken with aspirin or other blood thinners?
Ticlopidine Hydrochloride is sometimes combined with aspirin under close medical supervision (for example, after stent placement), but combining it with aspirin, other antiplatelet drugs, or anticoagulants increases the risk of bleeding, so this should only be done under a physician's direction.
Is Ticlopidine Hydrochloride safe for children?
No. The safety and efficacy of Ticlopidine Hydrochloride have not been established in children, so it is not recommended for pediatric use.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.