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Tiemonium Methylsulphate: Brands, Price & Uses in Bangladesh

Tiemonium Methylsulphate is an antimuscarinic (anticholinergic) antispasmodic used for the symptomatic relief of pain caused by smooth-muscle spasm of the gastrointestinal, biliary and more.

Forms:IM/IV InjectionTabletSyrupIV Injection

About Tiemonium Methylsulphate

Indications of Tiemonium Methylsulphate

Tiemonium Methylsulphate is an antimuscarinic (anticholinergic) antispasmodic used for the symptomatic relief of pain caused by smooth-muscle spasm of the gastrointestinal, biliary, and genitourinary tracts. Its use is established through decades of clinical marketing experience and local labeling rather than modern placebo-controlled FDA trials, so it is best described as a widely used, guideline-recognized symptomatic agent rather than a disease-modifying treatment.

Established / Labeled Uses

  • Painful spasm of the gastrointestinal tract, e.g. associated with gastroenteritis, enterocolitis, dysentery, diarrhoea, and irritable colonopathies
  • Biliary tract spasm, including biliary colic and cholecystitis-related pain
  • Spasm-related pain of the lower urinary tract, e.g. mild cystitis
  • Spasmodic dysmenorrhoea (painful uterine cramping)

Important Note

Tiemonium Methylsulphate treats the symptom of spasm and colicky pain; it is not a substitute for diagnosis and treatment of the underlying cause. Persistent, severe, or worsening abdominal or pelvic pain, fever, vomiting, or rectal bleeding should always be evaluated by a physician.

Dosage & Administration of Tiemonium Methylsulphate

Adults

FormulationUsual Adult Dose
Tablet (50 mg)1 tablet, 2–3 times daily (2–6 tablet-doses/day in divided doses)
Syrup (10 mg/5 ml)15–45 ml/day (3–9 teaspoonfuls) in 3 divided doses, i.e. 30–90 mg/day
Injection (5 mg/2 ml)1 ampoule, 1–3 times daily by slow IV or IM injection

Children

FormulationUsual Pediatric Dose
Syrup1.5–3 ml/kg body weight/day (approximately 3–6 mg/kg/day) in 3 divided doses, or as directed by the physician

Doses should always be individualised by the prescribing physician based on age, weight, severity of symptoms, and response to treatment. Tiemonium Methylsulphate tablets and syrup are usually taken before meals; the injection is given slowly by a healthcare professional.

Side Effects of Tiemonium Methylsulphate

Side effects with Tiemonium Methylsulphate are generally uncommon at recommended doses and are largely related to its anticholinergic activity. They include:

  • Dry mouth
  • Blurred vision or visual accommodation disturbances
  • Constipation
  • Urinary hesitancy
  • Drowsiness
  • Occasionally, hypotension and tachycardia

Seek medical attention if you notice severe or persistent side effects, an allergic reaction (rash, swelling, difficulty breathing), or eye pain with visual disturbance (possible sign of angle-closure glaucoma — see Contraindications).

Contraindications of Tiemonium Methylsulphate

Tiemonium Methylsulphate is contraindicated in patients with:

  • Known hypersensitivity to Tiemonium Methylsulphate or any component of the formulation
  • Narrow-angle (angle-closure) glaucoma
  • Urinary retention associated with bladder outlet or prostatic obstruction
  • Severe ulcerative colitis, particularly where there is risk of toxic megacolon
  • Myasthenia gravis

Frequently Asked Questions about Tiemonium Methylsulphate

What is Tiemonium Methylsulphate used for?

Tiemonium Methylsulphate is used to relieve painful spasms (cramping) of the stomach and intestines, the biliary tract, and the urinary tract, as well as painful menstrual cramps (spasmodic dysmenorrhoea). It works by relaxing smooth muscle that has gone into spasm.

How should I take Tiemonium Methylsulphate?

Take Tiemonium Methylsulphate exactly as prescribed by your physician. Tablets are usually swallowed whole with water, generally before meals; syrup should be measured with the provided measuring device. The injection form is given only by a healthcare professional, slowly into a vein or muscle. Do not change your dose without medical advice.

Can Tiemonium Methylsulphate be used during pregnancy or breastfeeding?

Tiemonium Methylsulphate should be used during pregnancy only if clearly needed, since human safety data are limited; a physician should weigh the potential benefit against any potential risk to the fetus before it is prescribed. Similarly, caution is advised during breastfeeding, and Tiemonium Methylsulphate should only be used by nursing mothers under medical supervision.

Who should not take Tiemonium Methylsulphate?

Tiemonium Methylsulphate should not be used by people with known hypersensitivity to it, narrow-angle glaucoma, urinary retention due to bladder outlet or prostate obstruction, severe ulcerative colitis with risk of toxic megacolon, or myasthenia gravis. Tell your physician about your full medical history before starting Tiemonium Methylsulphate.

What side effects can Tiemonium Methylsulphate cause?

Tiemonium Methylsulphate can cause dry mouth, blurred vision, constipation, difficulty starting urination, and drowsiness because of its anticholinergic action. Less commonly it may cause low blood pressure or a fast heartbeat. Contact your physician if side effects are severe or persistent, or if you notice eye pain with vision changes.

What should I do if I miss a dose or take too much Tiemonium Methylsulphate?

If you miss a dose of Tiemonium Methylsulphate, take it as soon as you remember unless it is almost time for the next dose — do not double the dose. If you or someone else has taken too much Tiemonium Methylsulphate and shows signs such as severe dry mouth, blurred vision, a fast heartbeat, agitation, or confusion, seek immediate medical attention or contact emergency/poison control services right away.

Disclaimer

The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.

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