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Tulobuterol Hydrochloride: Brands, Price & Uses in Bangladesh
Tulobuterol Hydrochloride is a selective, long-acting beta-2 adrenergic receptor agonist used as a bronchodilator.
About Tulobuterol Hydrochloride
Indications of Tulobuterol Hydrochloride
Tulobuterol Hydrochloride is a selective, long-acting beta-2 adrenergic receptor agonist used as a bronchodilator. Its established and guideline-supported uses include:
- Bronchial asthma: Maintenance/prophylactic treatment to control and prevent bronchospasm as part of a regular asthma-management regimen, used together with appropriate anti-inflammatory controller therapy (e.g., inhaled corticosteroids) rather than as monotherapy in persistent asthma, per current asthma-management guidelines.
- Chronic bronchitis and asthmatic bronchitis: Symptomatic relief of bronchospasm associated with chronic obstructive airway conditions.
- Pulmonary emphysema: Adjunct bronchodilator therapy for bronchospasm associated with emphysema.
Tulobuterol Hydrochloride is intended for regular, scheduled maintenance dosing and is not a fast-acting rescue medicine; a short-acting bronchodilator should always be available separately for sudden or acute symptoms.
Dosage & Administration of Tulobuterol Hydrochloride
Adults
| Indication | Dose |
|---|---|
| Bronchial asthma, chronic bronchitis, asthmatic bronchitis, pulmonary emphysema (maintenance) | Usual dose of Tulobuterol Hydrochloride: 2 mg (one tablet) orally twice daily; elderly or sensitive patients may start at 1 mg twice daily and increase to 2 mg twice daily after 7-10 days if needed. Maximum recommended dose is 6 mg per day in divided doses. |
Children (Syrup, 1 mg/5 mL)
| Age Group | Dose |
|---|---|
| 1-6 years | 2.5-5 mL twice daily |
| 6-12 years | 5-10 mL twice daily |
| Above 12 years | 10-20 mL twice daily |
An approximate weight-based dose of 40-80 mcg/kg/day in two divided doses may also be used under medical supervision. Doses of Tulobuterol Hydrochloride should always be individualized by the prescribing physician based on age, severity, and response.
Renal/Hepatic Impairment
Tulobuterol Hydrochloride is eliminated mainly by the kidneys and undergoes hepatic metabolism; therefore, caution and dose reduction should be considered in patients with significant renal or hepatic impairment, under medical supervision.
Where a transdermal patch of Tulobuterol Hydrochloride is used, one patch is typically applied once daily to clean, dry, non-irritated skin; the old patch must be removed before a new one is applied, and application sites should be rotated to reduce skin irritation.
Side Effects of Tulobuterol Hydrochloride
Common and clinically important side effects of Tulobuterol Hydrochloride include:
- Common: Fine tremor (especially of the hands), palpitations, tachycardia, headache, nervousness/CNS stimulation, insomnia.
- Cardiovascular: Hypertension, angina, and, rarely, arrhythmias, particularly with overuse or in predisposed patients.
- Gastrointestinal: Nausea, vomiting.
- Metabolic: Hypokalemia (see Precautions & Warnings), especially with concurrent diuretics or corticosteroids, or in acute severe exacerbations.
- Other: Vertigo/dizziness; with the patch formulation, application-site skin irritation or redness may occur.
Tremor is dose-related and tends to diminish with continued use. Patients should seek medical advice if side effects are severe or persistent.
Contraindications of Tulobuterol Hydrochloride
Tulobuterol Hydrochloride is contraindicated in:
- Patients with known hypersensitivity to tulobuterol, other sympathomimetic amines, or any component of the formulation.
- Use as the primary or sole treatment for acute bronchospasm or status asthmaticus. Because of its delayed onset of action (particularly the patch formulation of Tulobuterol Hydrochloride), it is not a rescue therapy, and a fast-acting bronchodilator must always be available separately for acute symptoms.
Frequently Asked Questions about Tulobuterol Hydrochloride
What is Tulobuterol Hydrochloride used for?
Tulobuterol Hydrochloride is a long-acting bronchodilator used for the prophylaxis and maintenance treatment of bronchospasm caused by bronchial asthma, chronic bronchitis, asthmatic bronchitis, and pulmonary emphysema. It is not intended for treating a sudden asthma attack.
Can I use Tulobuterol Hydrochloride to relieve a sudden asthma attack?
No. Tulobuterol Hydrochloride is a maintenance medicine with a relatively slow onset of action and is not a rescue therapy. You should always keep a fast-acting bronchodilator prescribed by your physician available for sudden or acute symptoms, and use Tulobuterol Hydrochloride only as regularly scheduled maintenance treatment.
What are the common side effects of Tulobuterol Hydrochloride?
The most common side effects of Tulobuterol Hydrochloride include hand tremor, palpitations, fast heartbeat, headache, and nervousness. Tremor is usually dose-related and tends to lessen with continued use. Contact your physician if side effects are severe or do not improve.
Is Tulobuterol Hydrochloride safe during pregnancy or breastfeeding?
The safety of Tulobuterol Hydrochloride during pregnancy and breastfeeding has not been well established. It should be used in pregnancy only if clearly needed, when the potential benefit justifies the potential risk to the fetus, and a physician should be consulted before use during breastfeeding as well.
Can Tulobuterol Hydrochloride be used with other asthma inhalers?
Tulobuterol Hydrochloride should not be used together with other long-acting beta-agonist (LABA) bronchodilator products, as this increases the risk of side effects such as tachycardia and tremor. In persistent asthma, it is generally used together with an anti-inflammatory controller medicine (such as an inhaled corticosteroid) rather than alone. Always inform your physician about all medicines you are using.
What should I do if I miss a dose or think I have taken too much Tulobuterol Hydrochloride?
If you miss a dose, take it as soon as you remember unless it is close to the next scheduled dose; do not double the dose. If you suspect an overdose of Tulobuterol Hydrochloride (symptoms may include severe tremor, rapid or irregular heartbeat, chest pain, or seizures), seek immediate medical attention or contact a poison control center right away.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.