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G-Water for injection5 ml/ampou
Gonoshasthaya Pharmaceuticals Limited
৳4.50
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Generic medicine
Water for injection: Brands, Price & Uses in Bangladesh
Water for injection is a sterile, pyrogen-free preparation of water that contains no antimicrobial agents, bacteriostatic additives, or other added substances.
About Water for injection
Indications of Water for injection
Water for injection is a sterile, pyrogen-free preparation of water that contains no antimicrobial agents, bacteriostatic additives, or other added substances. It is established and widely used as follows:
- Established/approved use: As a diluent or vehicle for reconstituting powdered injectable drugs (e.g., powder-for-injection antibiotics, biologics, and other lyophilized or powdered parenteral products) into a solution or suspension suitable for administration.
- Established/approved use: As a vehicle for diluting concentrated injectable drug solutions to the correct volume or concentration prior to intravenous, intramuscular, or subcutaneous administration, in accordance with the specific product's manufacturer instructions.
- Not indicated: Water for injection is not intended to be administered by itself as an intravenous fluid or for fluid/electrolyte replacement, and is not an oral or general-purpose rehydration product.
The specific drug product being reconstituted or diluted always determines the exact indication and route; Water for injection itself has no direct pharmacological/therapeutic action of its own.
Dosage & Administration of Water for injection
General principle
Water for injection does not have a therapeutic "dose" of its own. The volume of Water for injection used, and the resulting route of administration, is determined entirely by the specific manufacturer's instructions for the drug product being reconstituted or diluted.
| Use | Guidance |
|---|---|
| Reconstitution of powdered/lyophilized injectable drugs | Add the exact volume of Water for injection specified in the product labeling of the drug being reconstituted; mix gently until fully dissolved before use. |
| Dilution of concentrated injectable drug solutions | Dilute to the final volume/concentration specified in the manufacturer's instructions for the specific drug prior to intravenous, intramuscular, or subcutaneous administration. |
Important administration note
Water for injection must never be administered intravenously by itself, undiluted or as a bolus (see Contraindications). It must always be combined appropriately with the intended drug and, where required, with electrolytes/tonicity-adjusting agents before any parenteral fluid administration, strictly per the manufacturer's instructions for that specific product.
Side Effects of Water for injection
Water for injection itself does not produce pharmacological side effects when used correctly (i.e., only as a diluent/vehicle combined appropriately with the intended drug product). However, if Water for injection is mistakenly administered intravenously by itself, undiluted, serious adverse effects can occur due to hemolysis, including:
- Rupture of red blood cells (hemolysis) and release of hemoglobin into the plasma and urine
- Elevated blood potassium (hyperkalemia), which can cause dangerous heart rhythm disturbances
- Acute kidney injury
- Low blood pressure and circulatory collapse in severe cases
Any adverse effects experienced after administration of a solution prepared with Water for injection should generally be attributed to the specific active drug that was reconstituted or diluted, not to the diluent itself, provided it was used correctly.
Contraindications of Water for injection
Water for injection is absolutely contraindicated for direct intravenous administration by itself, undiluted, as a bolus or infusion. Because pure water is markedly hypotonic relative to blood, injecting it directly into the bloodstream causes osmotic lysis of red blood cells (hemolysis), which can result in severe, potentially life-threatening complications (e.g., hyperkalemia, hemoglobinuria, acute kidney injury, and circulatory collapse). Water for injection is intended solely as a sterile vehicle for reconstituting or diluting other injectable drug products with appropriate tonicity, and must never be given as a standalone parenteral fluid.
Frequently Asked Questions about Water for injection
What is Water for injection used for?
Water for injection is a sterile, pyrogen-free water used only as a diluent or vehicle to reconstitute powdered injectable drugs or to dilute concentrated injectable drug solutions before they are given to a patient. It is not a medicine on its own and is not given by itself.
Can Water for injection be given directly into a vein by itself?
No. Water for injection must never be injected intravenously by itself, undiluted. Because it is much more dilute than blood, injecting it alone into a vein can rupture red blood cells (hemolysis), which can raise blood potassium to dangerous levels, damage the kidneys, and be life-threatening. It must always be combined with the intended drug (and, when required, with electrolytes) as directed by the product instructions.
Is Water for injection the same as normal drinking water or IV saline?
No. Water for injection is specially purified and tested to be sterile and free of pyrogens (fever-causing substances) for use in preparing injectable medicines, and it is not meant to be swallowed. It is also different from intravenous saline or other electrolyte fluids, which contain added salts to make them safe to infuse alone; plain Water for injection is not.
Is Water for injection safe to use during pregnancy or breastfeeding?
Water for injection itself, when used correctly only as a diluent for another drug, does not add any active substance and is not known to pose an independent risk in pregnancy or breastfeeding. However, safety during pregnancy or breastfeeding actually depends on the specific medicine being reconstituted or diluted with Water for injection, so a physician should always be consulted about that medicine.
What happens if too much or too little Water for injection is used to reconstitute a drug?
Using the wrong volume of Water for injection changes the final concentration of the active drug, which can lead to an incorrect (too weak or too strong) dose being given. The exact volume specified in the manufacturer's instructions for that specific drug product must always be used, measured precisely under aseptic conditions.
What should be done if someone reacts badly after an injection prepared with Water for injection?
If any concerning symptoms occur after receiving an injection prepared using Water for injection, seek immediate medical attention or contact emergency services right away; do not attempt to manage a serious reaction at home, as it may be related to improper dilution or to the active drug itself and requires prompt medical evaluation.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.