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Medicine overview
Indications of Coralex DX
This is indicated for the treatment & prevention of osteoporosis, osteomalacia, tetany, hypoparathyroidism, disorders of osteogenesis. Also used as supplement in case of inadequate intake of Calcium in childhood diet, rickets, pregnancy & lactation, elderly patients. Other indications include pancreatitis, phosphate binder in chronic renal failure etc.
Composition
Each film coated tablet contains-
Calcium Carbonate 1500 mg (from Coral source) equivalent to elemental Calcium 600 mg
Vitamin D3 400 IU as Cholecalciferol
Or
Calcium Carbonate 1250 mg (from Coral source) equivalent to elemental Calcium 500 mg
Vitamin D3 200 IU as Cholecalciferol
Theropeutic Class
Specific mineral & vitamin combined preparations
Pharmacology
Adequate Calcium in the blood is so vital to a wide variety of bodily functions that our internal biochemistry will not tolerate a deficiency even for short periods. Clinical evidence suggests that Calcium is useful for the prevention and treatment of Osteoporosis and associated fractures. Vitamin D is also essential for healthy bones as it aids in Calcium absorption from the GI tract. In addition to this it stimulates bone formation. Clinical studies also show that Calcium and vitamin D has synergistic effects on bone growth as well as in Osteoporosis and fracture prevention.
Dosage & Administration of Coralex DX
One tablet in the morning and one tablet at night or as directed by the Physician
Dosage of Coralex DX
One tablet once or twice daily with plenty of water or as directed by the physician. Taking in full stomach ensures better absorption.
Interaction of Coralex DX
Oral Calcium can reduce the absorption of tetracycline & fluoride preparations and minimum 3 hours time should be allowed between ingestion of these medications. Thiazide diuretics reduces the renal excretion of Calcium. Phenytoin, barbiturates, glucocorticoids may induce metabolism of Vitamin D3. Concomitant ingestion of certain foods like spinach, cereals, milk and its derivatives may reduce the intestinal uptake of Calcium.
Contraindications
Hypersensitivity to any of the components, hypocalcaemia resulting from overdose of Vitamin D3, hyperparathyroidism, bone metastases, severe renal insufficiency, severe hypercalciuria, renal calculi etc.
Side Effects of Coralex DX
Flatulence, diarrhoea, constipation, upper GI discomfort etc. are rare manifestation. Hypercalcaemia due to prolong use has rarely been reported.
Pregnancy & Lactation
It should be used as directed by the physician during Pregnancy and Lactation.
Precautions & Warnings
In presence of mild hypercalciuria, careful monitoring with reduction of dose may be needed. Plasma and serum Calcium level should be monitored in mild to moderate renal impairment and also in case of long-term use. Patients with renal stones or with such previous history should also take precautions.
Overdose Effects of Coralex DX
At high doses it may result in nausea, vomiting, dizziness, anorexia, abdominal cramps, headache, constipation, irritability etc. Treatment includes cessation of therapy and adequate rehydration.
Storage Conditions
Store at temperature of below 30°C, protect from light & moisture. Keep out of reach of children.
Drug Classes
Specific mineral & vitamin combined preparations
Mode Of Action
This is a Calcium and Vitamin D3 preparation where Calcium Carbonate is sourced from coral origin. The Calcium Carbonate from Coral has a chemical structure that is very similar to the composition of human bone. Coral Calcium is similar to other sources but ensures better absorption. Vitamin D3 aids in the absorption of Calcium from GI tract and helps to maintain Calcium balance in the body.
Pregnancy
This can be given to pregnant and lactating mothers as per recommendation of physician.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.