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Ezylife100 ml
Oral Solution
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Medicine overview
Indications of Ezylife 100 ml
Ezylife 100 ml is indicated in the following conditions-
Constipation of any etiology
Relief from prolonged & recurrent constipation
Bowel clearance before surgery, childbirth or radiological investigations.
Theropeutic Class
Osmotic purgatives
Pharmacology
Sodium picosulfate is a stimulant laxative that in conjunction with magnesium citrate, produces a purgative effect on stools.
Absorption
It inhibits the absorption of water and electrolytes, and increases their secretion into the intestinal lumen.
Metabolism
It is hydrolyzed by colonic bacterial enzyme, sulfatase, to form an active metabolite bis-(p-hydroxy-phenyl)-pyridyl-2-methane (BHPM), which acts directly on the colonic mucosa to stimulate colonic peristalsis.
Dosage & Administration of Ezylife 100 ml
Notes:For oral administration. The following dosages are recommended to be taken at night to produce evacuation the following morning. It is recommended to start with the lowest dose. The dose may be adjusted up to the maximum recommended dose to produce regular stools. The maximum recommended daily dose should not be exceeded:Adults and children over 10 years of age- Tablet: 5-10 mg per day
Oral Solution
Dosage:5-10 ml or one to two teaspoonful per day
Children aged 4-10 years- Tablet
Dosage:2.5-5 mg per day
Oral Solution
Dosage:2.5-5 ml or Half to one teaspoonful per day
Children under 4 years of age- Oral Solution
Dosage:0.25 ml/kg body weight per day
| Condition | Dosage | Notes |
|---|---|---|
| For oral administration. The following dosages are recommended to be taken at night to produce evacuation the following morning. It is recommended to start with the lowest dose. The dose may be adjusted up to the maximum recommended dose to produce regular stools. The maximum recommended daily dose should not be exceeded:Adults and children over 10 years of age- Tablet: 5-10 mg per day | ||
| Oral Solution | 5-10 ml or one to two teaspoonful per day | |
| Children aged 4-10 years- Tablet | 2.5-5 mg per day | |
| Oral Solution | 2.5-5 ml or Half to one teaspoonful per day | |
| Children under 4 years of age- Oral Solution | 0.25 ml/kg body weight per day |
Dosage of Ezylife 100 ml
Notes:For oral administration. The following dosages are recommended to be taken at night to produce evacuation the following morning. It is recommended to start with the lowest dose. The dose may be adjusted up to the maximum recommended dose to produce regular stools. The maximum recommended daily dose should not be exceeded:Adults and children over 10 years of age- Tablet: 5-10 mg per day
Oral Solution
Dosage:5-10 ml or one to two teaspoonful per day
Children are aged 4-10 years- Tablet
Dosage:2.5-5 mg per day
Oral Solution
Dosage:2.5-5 ml or Half to one teaspoonful per day
Children under 4 years of age- Oral Solution
Dosage:0.25 ml/kg body weight per day
| Condition | Dosage | Notes |
|---|---|---|
| For oral administration. The following dosages are recommended to be taken at night to produce evacuation the following morning. It is recommended to start with the lowest dose. The dose may be adjusted up to the maximum recommended dose to produce regular stools. The maximum recommended daily dose should not be exceeded:Adults and children over 10 years of age- Tablet: 5-10 mg per day | ||
| Oral Solution | 5-10 ml or one to two teaspoonful per day | |
| Children are aged 4-10 years- Tablet | 2.5-5 mg per day | |
| Oral Solution | 2.5-5 ml or Half to one teaspoonful per day | |
| Children under 4 years of age- Oral Solution | 0.25 ml/kg body weight per day |
Interaction of Ezylife 100 ml
The concomitant use of diuretics or adreno-corticosteroids may increase the risk of electrolyte imbalance if excessive doses are taken. Concurrent administration of antibiotics may reduce the laxative action of this product.
Contraindications
Ileus or intestinal obstruction, severe painful and/or feverish acute abdominal conditions (e.g. appendicitis) potentially associated with nausea and vomiting, acute inflammatory bowel diseases, severe dehydration, known hypersensitivity to Ezylife 100 ml or any other component of the product.
Side Effects of Ezylife 100 ml
Hypersensitivity, dizziness, syncope, vasovagal response, gastrointestinal disorders, diarrhea, abdominal pain and abdominal cramps, nausea, vomiting.
Pregnancy & Lactation
Pregnancy: There are no adequate and well-controlled studies in pregnant women. Long experience has shown no evidence of undesirable or damaging effects during pregnancy.Lactation: Clinical data show that neither the active moiety of sodium Picosulfate (BHPM or bis-(p hydroxyphenyl)-pyridyl-2-methane) nor its glucuronides are excreted into the milk of healthy lactating females.
Precautions & Warnings
Prolonged excessive use may lead to fluid and electrolyte imbalance and hypokalemia. Harmful for those suffering from alcoholism. To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease or epilepsy.
Overdose Effects of Ezylife 100 ml
Laxatives when taken in chronic overdosage may cause chronic diarrhea, abdominal pain, hypokalemia, secondary hyperaldosteronism, and renal calculi. Renal tubular damage, metabolic alkalosis, and muscle weakness secondary to hypokalemia have also been described in association with chronic laxative abuse.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Classes
Osmotic purgatives
Mode Of Action
Ezylife 100 ml is a triarylmethane group derivative stimulant laxative. After oral administration it is activated by the colonic bacteria and acts locally in the colon. The active form then stimulates the nerve endings of the intestinal wall and results in colonic peristalsis with promotion of accumulation of water and electrolytes in the colonic lumen. This results in stimulation of defecation, reduction of transit time and softening of the stool. Stimulation of the rectum causes increased motility and a feeling of rectal fullness. The rectal effect may help to restore the "call to stool".
Pregnancy
There are no reports of undesirable or damaging effects during pregnancy or to the foetus attributable to the use of this product. Use of the drug should be avoided during the first trimester. Clinical data show that neither the active moiety of sodium Picosulfate (BHPM or bis-(p hydroxyphenyl)-pyridyl-2-methane) nor its glucuronides are excreted into the milk of healthy lactating females.
Frequently Asked Questions
What is Ezylife 100 ml used for?
Sodium Picosulfate is indicated in the following conditions- Constipation of any etiology Relief from prolonged & recurrent constipation Bowel clearance before surgery, childbirth or radiological investigations.
What is the dosage of Ezylife 100 ml?
For oral administration. The following dosages are recommended to be taken at night to produce evacuation the following morning. It is recommended to start with the lowest dose. The dose may be adjusted up to the maximum recommended dose to produce regular stools. The maximum recommended daily dose should not be exceeded:Adults and children over 10 years of age- Tablet: 5-10 mg per day. Oral Solut…
What are the side effects of Ezylife 100 ml?
Hypersensitivity, dizziness, syncope, vasovagal response, gastrointestinal disorders, diarrhea, abdominal pain and abdominal cramps, nausea, vomiting.
Who should not take Ezylife 100 ml?
Ileus or intestinal obstruction, severe painful and/or feverish acute abdominal conditions (e.g. appendicitis) potentially associated with nausea and vomiting, acute inflammatory bowel diseases, severe dehydration, known hypersensitivity to Sodium Picosulfate or any other component of the product.
What precautions should be taken with Ezylife 100 ml?
Prolonged excessive use may lead to fluid and electrolyte imbalance and hypokalemia. Harmful for those suffering from alcoholism. To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease or epilepsy.
Is Ezylife 100 ml safe during pregnancy and breastfeeding?
Pregnancy: There are no adequate and well-controlled studies in pregnant women. Long experience has shown no evidence of undesirable or damaging effects during pregnancy.Lactation: Clinical data show that neither the active moiety of sodium Picosulfate (BHPM or bis-(p hydroxyphenyl)-pyridyl-2-methane) nor its glucuronides are excreted into the milk of healthy lactating females.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.