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Gentian Violet2%

Topical Solution

Gentian Violet
ByMomotaz Pharmaceuticals Ltd.
MRP ৳ 12.0010 % Off
Best PriceTk 10.80/15 ml solution
Out Of Stock
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Medicine overview

Indications of Gentian Violet 2%

Topical antiseptic as first aid to help prevent infection in minor cuts, scrapes and burns

Theropeutic Class

Crystal violet/ Gentian violet preparations

Pharmacology

In aqueous solutions Gentian violet (GV) dissociates into positive (GV+)and negative ions (Cl-) that penetrate through the wall and membrane of both gram-positive and gram-negative bacterial cells. The GV+ interacts with negatively charged components of bacterial cells including the lipopolysaccharide (on the cell wall), the peptidoglycan and DNA. A similar cell penetration and DNA binding process is thought to take place for fungal cells as well. Because Gentian violet is a mutagen and mitotic poison, cell growth is consequently inhibited. A photodynamic action of Gentian Violet 2%, apparently mediated by a free-radical mechanism, has recently been described in bacteria and in the protozoan T. cruzi. Evidence also suggests that Gentian Violet 2% dissipates the bacterial (and mitochondrial) membrane potential by inducing permeability. This is followed by respiratory inhibition. This anti-mitochondrial activity might explain Gentian Violet 2%'s efficacy towards both bacteria and yeast with relatively mild effects on mammalian cells.

Dosage & Administration of Gentian Violet 2%

Clean the affected area and apply a small amount of this product on the area 1 to 3 times daily. May be covered with a sterile bandage.

Dosage of Gentian Violet 2%

Clean the affected area and apply a small amount of this product on the area 1 to 3 times daily. May be covered with a sterile bandage.

Interaction of Gentian Violet 2%

There are no known drug interactions and none well documented.

Contraindications

Do not apply to an ulcerative lesion as this may cause tattoing of the skin.

Side Effects of Gentian Violet 2%

Redness, irritation, swelling or pain persists or increases of if infection occurs.

Pregnancy & Lactation

Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Precautions & Warnings

Stop use if the condition persists or gets worse. Do not use longer than 1 week.

Drug Classes

Crystal violet/ Gentian violet preparations

Mode Of Action

In aqueous solutions Gentian violet (GV) dissociates into positive (GV+)and negative ions (Cl-) that penetrate through the wall and membrane of both gram-positive and gram-negative bacterial cells. The GV+ interacts with negatively charged components of bacterial cells including the lipopolysaccharide (on the cell wall), the peptidoglycan and DNA. A similar cell penetration and DNA binding process is thought to take place for fungal cells as well. Because Gentian violet is a mutagen and mitotic poison, cell growth is consequently inhibited. A photodynamic action of Gentian Violet 2%, apparently mediated by a free-radical mechanism, has recently been described in bacteria and in the protozoan T. cruzi. Evidence also suggests that Gentian Violet 2% dissipates the bacterial (and mitochondrial) membrane potential by inducing permeability. This is followed by respiratory inhibition. This anti-mitochondrial activity might explain Gentian Violet 2%'s efficacy towards both bacteria and yeast with relatively mild effects on mammalian cells.

Pregnancy

Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Frequently Asked Questions

What is Gentian Violet 2% used for?

Topical antiseptic as first aid to help prevent infection in minor cuts, scrapes and burns

What is the dosage of Gentian Violet 2%?

Clean the affected area and apply a small amount of this product on the area 1 to 3 times daily. May be covered with a sterile bandage.

What are the side effects of Gentian Violet 2%?

Redness, irritation, swelling or pain persists or increases of if infection occurs.

Who should not take Gentian Violet 2%?

Do not apply to an ulcerative lesion as this may cause tattoing of the skin.

What precautions should be taken with Gentian Violet 2%?

Stop use if the condition persists or gets worse. Do not use longer than 1 week.

Is Gentian Violet 2% safe during pregnancy and breastfeeding?

Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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