Isobgul3.5 gm
Sachet
Medicine overview
Indications of Isobgul 3.5 gm
Theropeutic Class
Pharmacology
Most of the Ispaghula reach the caecum within four hours after ingestion in an intact and highly polymerized form.
Ispaghula husk significantly increases the level of stool moisture, as well as wet and dry stool weight and shorten gastrointestinal transit time. Anaerobic fermentation of the soluble non-starch polysaccharides from Ispaghula seed results in the production of short chain fatty acids, acetate, propionate and butyrate in the intestine.
It is assumed that Ispaghula increases the activity of cholesterol alpha hydroxylase, HMG-CoA reductase and fractional turnover of both chenodeoxycholic and cholic acids.
Butyric acid is the preferred oxidative substrate for colonocytes and may be helpful in the treatment of ulcerative colitis.
Dosage of Isobgul 3.5 gm
| Condition | Dosage | Notes |
|---|---|---|
| Constipation | Adult: 3.5 g 1-3 times daily | Mix with a full glass of liq |
| Child | ≤12 yr Each level 5-mL spoonful contains 1.75 g: Half to 1 level 5-mL spoonful bid (morning and evening) to be dissolved in water | |
| Mild to moderate hypercholesterolaemia | Adult: As adjunct to lipid-lowering diet: 7.5-10 g daily | Mix with a full glass of liq |
Administration of Isobgul 3.5 gm
Interaction of Isobgul 3.5 gm
Contraindications
Side Effects of Isobgul 3.5 gm
Pregnancy & Lactation
Precautions & Warnings
Overdose Effects of Isobgul 3.5 gm
Storage Conditions
Frequently Asked Questions
What is Isobgul 3.5 gm used for?
This medicine contains ispaghula husk which is a bulking agent. This means that when it is taken with water it increases the size of the faeces (stools) and helps solid waste to pass through the body. Ispaghula Husk sachets are used to treat constipation and in conditions where it is better for the patient to have soft stools. They are also used for patients who require a high fibre diet
What is the dosage of Isobgul 3.5 gm?
Constipation: Adult: 3.5 g 1-3 times daily. Mix with a full glass of liq. Child: ≤12 yr Each level 5-mL spoonful contains 1.75 g: Half to 1 level 5-mL spoonful bid (morning and evening) to be dissolved in water. Mild to moderate hypercholesterolaemia: Adult: As adjunct to lipid-lowering diet: 7.5-10 g daily. Mix with a full glass of liq.
What are the side effects of Isobgul 3.5 gm?
Abdominal distention, flatulence, GI impaction, GI obstruction, hypersensitivity reactions e.g. rhinitis, conjunctivitis, bronchospasm and anaphylaxia; cutaneous symptoms (e.g. exanthema and/or pruritus).
Who should not take Isobgul 3.5 gm?
Pre-existing faecal impaction, intestinal obstruction, natural or drug-induced reduction of gut motility, colonic atony e.g. senile megacolon.
What precautions should be taken with Isobgul 3.5 gm?
Patient with swallowing difficulty. Children.
Is Isobgul 3.5 gm safe during pregnancy and breastfeeding?
No adverse effects of has been reported in pregnancy & lactation.
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.