Livolite200 mg
Capsule
Andrographis paniculata
Square Pharmaceuticals PLC.
Product Code : 9735
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Medicine overview
Indications of Livolite 200 mg
Livolite 200 mg is indicated in-
Viral fever
Flu
Common cold
Sinusitis
Upper respiratory tract infection
Viral hepatitis.
Theropeutic Class
Herbal and Nutraceuticals
Pharmacology
Andrographis compounds have shown antiviral properties which appear to inhibit glycoproteins in the virus. This impedes the ability of viruses to invade cells and replicate. It also has a major effect activating the general defense functions of the immune system by stimulating the production of antibodies as well as non-specific immune responses such as increased macrophage phagocytosis, rather than by any direct antimicrobial activity. Andrographis has flavonoids, which always have an anti-inflammatory effect. In vitro studies have shown that the flavonoid activities suppressed the genetic expression of neutrophils. Similarly, studies have indicated that a variety of inflammatory proteins, including COX-2, are reduced by the presence of Andrographoloid.The aerial parts and their constituent andrographolides have antihepato-toxic activity in vitro and in vivo. In vitro studies have shown that intraperitoneal administration of a methanol extract of the aerial parts to mice reduced hepatotoxicity induced by carbon tetrachloride CCl4, and reversed CCl4 induced histopathological changes in the liver. Intraperitoneal administration of andrographolide to mice inhibited the CCl4 induced increase in the activity of serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, alkaline phosphatase, bilirubin and hepatic triglycerides. Andrographolide, the major antihepatotoxic component of the plant, exerted a pronounced protective effect in rats against hepato-toxicity induced by CCl4, Dgalactosamine, paracetamol and ethanol.Moreover, andrographolide and related diterpenes are choleretic, antidiarrheal, immunostimulant, antimalarial, antipyretic and active in urinary tract infections.
Dosage & Administration of Livolite 200 mg
Age 18 and above: 1 capsule 3 times daily after meal for 5 to 10 days.12 to 17 years: 1 capsule 2 times daily after meal for 5 to 10 days.4 to 11 years: 1 capsule daily after meal for 5 to 10 days or as directed by the physician.
Interaction of Livolite 200 mg
May have a synergistic effect with isoniazid.
Contraindications
Andrographis is contraindicated in cases of known allergy to plants of the acanthaceae family
Side Effects of Livolite 200 mg
Large oral doses may cause gastric discomfort, vomiting and loss of appetite. These side-effects appear to be due to the bitter taste of andrographolide.
Pregnancy & Lactation
Andrographis should not be used during pregnancy or lactation.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.