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Anadol50 mg
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Lucidol50 mg
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Medicine overview
Indications of Lucidol 50 mg
Tramadol is used for the treatment of moderate to severe painful conditions. These include:
Postoperative pain
Colic and spastic pain
Cancer pain
Joint pain
Neck and back pain
Pain associated with osteoporosis.
Theropeutic Class
Opioid analgesics
Pharmacology
Tramadol is a centrally acting synthetic analgesic compound.
Absorption
Thus it modifies the transmission of pain impulses by activating both descending serotonergic pathways and noradrenergic pathways involved in analgesia.
Distribution
The analgesic effects of Tramadol are mediated via stimulation of mu-opioid receptors and indirect modulation of central monoaminergic inhibitory pathways.
Excretion
It inhibits the re uptake of neurotransmitters- serotonin and noradrenaline.
Dosage & Administration of Lucidol 50 mg
Capsule or Tablet
Dosage:Usual doses are 50 to 100 mg every four to six hours
Notes:For acute pain an initial dose of 100 mg is required. For chronic painful conditions an initial dose of 50 mg is recommended. Subsequent doses should be 50 to 100 mg administered 4-6 hourly. The dose level and frequency of dosing will depend on the severity of the pain. The total daily dosage by mouth should not exceed 400 mg
Sustained Release Capsule or Tablet
Dosage:One SR capsule or tablet every 12 hours, for example first one in the morning and then at the same time in the evening
Notes:The number of capsules taken at a time will depend upon severity of pain, but it should not be taken more frequently than every 12 hours. The total daily dosage by mouth should not exceed 400 mg
Injection
Dosage:A dose of 50-100 mg may be given every 4 to 6 hours by intramuscular or by intravenous infusion
Notes:For the treatment of postoperative pain,the initial dose is 100 mg followed by 50 mg every 10 to 20 minutes if necessary to a maximum of 250 mg in the first hour. Thereafter, doses are 50 to 100 mg every 4 to 6 hours up to a total daily dose of 600 mg
Suppository
Dosage:Tramadol suppository should be administered rectally
Notes:For adults usual dose is 100 mg Lucidol 50 mg 6 hourly. In general, 400 mg Lucidol 50 mg (4 Tramadol suppository) per day sufficient. However, for the treatment of Cancer pain and severe pain after operations much higher daily doses can be used
| Condition | Dosage | Notes |
|---|---|---|
| Capsule or Tablet | Usual doses are 50 to 100 mg every four to six hours | For acute pain an initial dose of 100 mg is required. For chronic painful conditions an initial dose of 50 mg is recommended. Subsequent doses should be 50 to 100 mg administered 4-6 hourly. The dose level and frequency of dosing will depend on the severity of the pain. The total daily dosage by mouth should not exceed 400 mg |
| Sustained Release Capsule or Tablet | One SR capsule or tablet every 12 hours, for example first one in the morning and then at the same time in the evening | The number of capsules taken at a time will depend upon severity of pain, but it should not be taken more frequently than every 12 hours. The total daily dosage by mouth should not exceed 400 mg |
| Injection | A dose of 50-100 mg may be given every 4 to 6 hours by intramuscular or by intravenous infusion | For the treatment of postoperative pain,the initial dose is 100 mg followed by 50 mg every 10 to 20 minutes if necessary to a maximum of 250 mg in the first hour. Thereafter, doses are 50 to 100 mg every 4 to 6 hours up to a total daily dose of 600 mg |
| Suppository | Tramadol suppository should be administered rectally | For adults usual dose is 100 mg Lucidol 50 mg 6 hourly. In general, 400 mg Lucidol 50 mg (4 Tramadol suppository) per day sufficient. However, for the treatment of Cancer pain and severe pain after operations much higher daily doses can be used |
Dosage of Lucidol 50 mg
Capsule or Tablet
Dosage:Usual doses are 50 to 100 mg every four to six hours
Notes:For acute pain an initial dose of 100 mg is required. For chronic painful conditions an initial dose of 50 mg is recommended. Subsequent doses should be 50 to 100 mg administered 4-6 hourly. The dose level and frequency of dosing will depend on the severity of the pain. The total daily dosage by mouth should not exceed 400 mg
Sustained Release Capsule or Tablet
Dosage:One SR capsule or tablet every 12 hours, for example first one in the morning and then at the same time in the evening
Notes:The number of capsules taken at a time will depend upon severity of pain, but it should not be taken more frequently than every 12 hours. The total daily dosage by mouth should not exceed 400 mg
Injection
Dosage:A dose of 50-100 mg may be given every 4 to 6 hours by intramuscular or by intravenous infusion
Notes:For the treatment of postoperative pain,the initial dose is 100 mg followed by 50 mg every 10 to 20 minutes if necessary to a maximum of 250 mg in the first hour. Thereafter, doses are 50 to 100 mg every 4 to 6 hours up to a total daily dose of 600 mg
Suppository
Dosage:Tramadol suppository should be administered rectally
Notes:For adults usual dose is 100 mg Lucidol 50 mg 6 hourly. In general, 400 mg Lucidol 50 mg (4 Tramadol suppository) per day sufficient. However, for the treatment of Cancer pain and severe pain after operations much higher daily doses can be used
| Condition | Dosage | Notes |
|---|---|---|
| Capsule or Tablet | Usual doses are 50 to 100 mg every four to six hours | For acute pain an initial dose of 100 mg is required. For chronic painful conditions an initial dose of 50 mg is recommended. Subsequent doses should be 50 to 100 mg administered 4-6 hourly. The dose level and frequency of dosing will depend on the severity of the pain. The total daily dosage by mouth should not exceed 400 mg |
| Sustained Release Capsule or Tablet | One SR capsule or tablet every 12 hours, for example first one in the morning and then at the same time in the evening | The number of capsules taken at a time will depend upon severity of pain, but it should not be taken more frequently than every 12 hours. The total daily dosage by mouth should not exceed 400 mg |
| Injection | A dose of 50-100 mg may be given every 4 to 6 hours by intramuscular or by intravenous infusion | For the treatment of postoperative pain,the initial dose is 100 mg followed by 50 mg every 10 to 20 minutes if necessary to a maximum of 250 mg in the first hour. Thereafter, doses are 50 to 100 mg every 4 to 6 hours up to a total daily dose of 600 mg |
| Suppository | Tramadol suppository should be administered rectally | For adults usual dose is 100 mg Lucidol 50 mg 6 hourly. In general, 400 mg Lucidol 50 mg (4 Tramadol suppository) per day sufficient. However, for the treatment of Cancer pain and severe pain after operations much higher daily doses can be used |
Interaction of Lucidol 50 mg
In general, physician need not be concerned about drugs interacting with Tramadol. The monoamine oxidase (MAO) inhibitors represent the only drug class not recommended for combination with Tramadol. Concomitant administration of carbamazepine with Tramadol causes a significant increase in Tramadol metabolism and it requires to increase the dose of Tramadol.
Contraindications
Tramadol is contraindicated in persons having hypersensitivity to this drug. It is also contraindicated in acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs.
Side Effects of Lucidol 50 mg
Commonly occurring side-effects are dizziness/vertigo, nausea, constipation, headache, somnolence, vomiting, pruritus, CNS stimulation, asthenia, sweating, dyspepsia, dry mouth, diarrhoea. Less commonly occurring side-effects include malaise, allergic reaction, weight loss, vasodilatation, palpitations, abdominal pain, anorexia, flatulence, GI bleeding, hepatitis, stomatitis etc.
Pregnancy & Lactation
Safe use of Tramadol in pregnancy has not been established. Tramadol has been shown to cross the placenta. There are no adequate and well-controlled studies in pregnant women. Therefore, Tramadol should be used during pregnancy only if the potential benefit justifies the risk to the foetus. Lucidol 50 mg should not be administered during breast feeding as Tramadol and its metabolites have been detected in breast milk.
Precautions & Warnings
Respiratory depression: When large doses of tramadol are administered with anaesthetic with anaesthetic medications or alcohol, respiratory depression may result. Therefore, tramadol should be administered cautiously in patients at risk for respiratory depression.Opioid dependence: Tramadol is not recommended for patients who are dependent on opioids.Concomitant CNS depressants: Tramadol should be used with caution and in reduced dosages when administering to patients receiving CNS depressants such as alcohol, opioids, anesthetic agents, phenothiazines, tranquilizers or sedative hypnotics.Concomitant MAO inhibitors: Tramadol should be used with great caution in patients taking MAO inhibitors, since tramadol inhibits the uptake of norepinephrine and serotonin.Tramadol should be used with caution in patients with increased intracranial pressure or head injury and patients with acute abdominal conditions.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Use In Special Populations
In children from the age of 1 year Lucidol 50 mg can be given in a dose of 1-2 mg/kg body weight. However,suppository (100 mg Lucidol 50 mg) should not be administered in children and adolescents below the age of 14 years. Lucidol 50 mg 100 mg SR Capsules have not been studied in children. Therefore, safety and efficacy have not been established and the product should not be used in children.
Drug Classes
Opioid analgesics
Mode Of Action
Tramadol is a centrally acting synthetic analgesic compound. It inhibits the re uptake of neurotransmitters- serotonin and noradrenaline. Thus it modifies the transmission of pain impulses by activating both descending serotonergic pathways and noradrenergic pathways involved in analgesia. The analgesic effects of Tramadol are mediated via stimulation of mu-opioid receptors and indirect modulation of central monoaminergic inhibitory pathways.
Pregnancy
Safe use of Tramadol in pregnancy has not been established. Tramadol has been shown to cross the placenta. There are no adequate and well-controlled studies in pregnant women. Therefore, Tramadol should be used during pregnancy only if the potential benefit justifies the risk to the foetus. Lucidol 50 mg should not be administered during breast feeding as Tramadol and its metabolites have been detected in breast milk.
Pediatric Uses
In children from the age of 1 year Lucidol 50 mg can be given in a dose of 1-2 mg/kg body weight. However,suppository (100 mg Lucidol 50 mg) should not be administered in children and adolescents below the age of 14 years. Lucidol 50 mg 100 mg SR Capsules have not been studied in children. Therefore, safety and efficacy have not been established and the product should not be used in children.
Frequently Asked Questions
What is Lucidol 50 mg used for?
Tramadol is used for the treatment of moderate to severe painful conditions. These include: Postoperative pain Colic and spastic pain Cancer pain Joint pain Neck and back pain Pain associated with osteoporosis.
What is the dosage of Lucidol 50 mg?
Capsule or Tablet: Usual doses are 50 to 100 mg every four to six hours. For acute pain an initial dose of 100 mg is required. For chronic painful conditions an initial dose of 50 mg is recommended. Subsequent doses should be 50 to 100 mg administered 4-6 hourly. The dose level and frequency of dosing will depend on the severity of the pain.The total daily dosage by mouth should not exceed 400 mg.…
What are the side effects of Lucidol 50 mg?
Commonly occurring side-effects are dizziness/vertigo, nausea, constipation, headache, somnolence, vomiting, pruritus, CNS stimulation, asthenia, sweating, dyspepsia, dry mouth, diarrhoea. Less commonly occurring side-effects include malaise, allergic reaction, weight loss, vasodilatation, palpitations, abdominal pain, anorexia, flatulence, GI bleeding, hepatitis, stomatitis etc.
Who should not take Lucidol 50 mg?
Tramadol is contraindicated in persons having hypersensitivity to this drug. It is also contraindicated in acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs.
What precautions should be taken with Lucidol 50 mg?
Respiratory depression: When large doses of tramadol are administered with anaesthetic with anaesthetic medications or alcohol, respiratory depression may result. Therefore, tramadol should be administered cautiously in patients at risk for respiratory depression.Opioid dependence: Tramadol is not recommended for patients who are dependent on opioids.Concomitant CNS depressants: Tramadol should be…
Is Lucidol 50 mg safe during pregnancy and breastfeeding?
Safe use of Tramadol in pregnancy has not been established. Tramadol has been shown to cross the placenta. There are no adequate and well-controlled studies in pregnant women. Therefore, Tramadol should be used during pregnancy only if the potential benefit justifies the risk to the foetus. Tramadol Hydrochloride should not be administered during breast feeding as Tramadol and its metabolites have…
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.