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Zif-A48 mg+0.5
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Nuviron48 mg+0.5 mg+22.5 mg
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Medicine overview
Indications of Nuviron 48 mg+0.5 mg+22.5 mg
Nuviron 48 mg+0.5 mg+22.5 mg is indicated on prophylaxis of iron deficiency especially when inadequate diet calls for supplementary zinc and iron during pregnancy and anemia.
Theropeutic Class
Iron, Vitamin & Mineral Combined preparation
Pharmacology
Nuviron 48 mg+0.5 mg+22.5 mg when administered is converted to ferric form and immediately is reduced to the ferrous form into the stomach.
Absorption
This reduced ferrous form is then transferred to the duodenum where it is highly absorbed.
Distribution
These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain numerous body functions. Zinc is essential to numerous physiological processes, including the function of many enzymes in the body.
Metabolism
Folic Acid itself is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase in liver. Folic acid enhances chemical reactions that contribute to the production of red blood cells, the manufacture of DNA needed for cell replication and the metabolism of amino acids (compounds necessary for the manufacture of proteins).
Dosage & Administration of Nuviron 48 mg+0.5 mg+22.5 mg
Adult & Elderly
Dosage:One tablet a day before or after meal (food independent absorption) or as directed by the physician
Notes:In more severe cases, two tablets a day may be required as prescribed by the physician. Safety and effectiveness in pediatric patients have not been established
| Condition | Dosage | Notes |
|---|---|---|
| Adult & Elderly | One tablet a day before or after meal (food independent absorption) or as directed by the physician | In more severe cases, two tablets a day may be required as prescribed by the physician. Safety and effectiveness in pediatric patients have not been established |
Dosage of Nuviron 48 mg+0.5 mg+22.5 mg
Adult & Elderly
Dosage:One tablet a day before or after meal (food independent absorption) or as directed by the physician
Notes:In more severe cases, two tablets a day may be required as prescribed by the physician
Pediatric patients
Dosage:Safety and effectiveness in pediatric patients have not been established
| Condition | Dosage | Notes |
|---|---|---|
| Adult & Elderly | One tablet a day before or after meal (food independent absorption) or as directed by the physician | In more severe cases, two tablets a day may be required as prescribed by the physician |
| Pediatric patients | Safety and effectiveness in pediatric patients have not been established |
Interaction of Nuviron 48 mg+0.5 mg+22.5 mg
Iron chelates with tetracycline. Since oral iron products interfere with absorption of oral tetracycline antibiotics, Nuviron 48 mg+0.5 mg+22.5 mg should not be taken within two hours of each other. Occasional gastrointestinal discomfort may be minimized by taking with meals. Absorption of iron may be impaired by concurrent administrations of penicillamine and antacid. In patients with renal failure, a risk of zinc accumulation may exist.
Contraindications
Nuviron 48 mg+0.5 mg+22.5 mg is contraindicated in patients with haemolytic anaemia and in conditions with increased hypersensitivity to any of its components and increased body iron content.
Side Effects of Nuviron 48 mg+0.5 mg+22.5 mg
Side effects of Nuviron 48 mg+0.5 mg+22.5 mg supplementation are mild and transient. These include epigastric pain, nausea, constipation, vomiting, diarrhoea, heart burn, etc. Allergic sensitization has been reported following both oral and parenteral administration of folic acid.
Pregnancy & Lactation
If pregnant, or planning to become pregnant or are currently breast-feeding please contact your physician, before taking or continuing the drug. Administration in first trimester of pregnancy should be avoided unless definite evidence of iron deficiency is observed. Prophylaxis of iron deficiency is justified during the remainder of pregnancy specifically when zinc supplementation is required.
Precautions & Warnings
Care should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anemia or red cell aplasia. Failure to respond to treatment may indicate other causes of anemia and should be further investigated.
Overdose Effects of Nuviron 48 mg+0.5 mg+22.5 mg
The clinical course of acute iron overdosage can be variable. Initial symptoms may include abdominal pain, nausea, vomiting, diarrhoea, tarry stools, melena, hematemesis, hypotension, tachycardia, metabolic acidosis, hyperglycemia, dehydration, drowsiness, pallor, cyanosis, lassitude, seizures, shock and coma.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Classes
Iron, Vitamin & Mineral Combined preparation
Mode Of Action
Ferrous Ascorbate, Folic Acid & Zinc is a combination of three nutritional supplements. Nuviron 48 mg+0.5 mg+22.5 mg is a combination of iron and vitamin C. Iron replenishes the iron stores in your body and corrects iron deficiency anemia. Vitamin C (ascorbate) is added to enhance the absorption of iron in the body. Folic Acid is a form of vitamin B. It plays a vital role in the formation of red blood cells, which carry oxygen throughout the body. It is also essential in pregnancy due to its role in the development of the unborn baby's brain and spinal cord. Zinc is a micromineral that provides nutrition.
Pregnancy
If pregnant, or planning to become pregnant or are currently breast-feeding please contact your physician, before taking or continuing the drug. Administration in first trimester of pregnancy should be avoided unless definite evidence of iron deficiency is observed. Prophylaxis of iron deficiency is justified during the remainder of pregnancy specifically when zinc supplementation is required.
Frequently Asked Questions
What is Nuviron 48 mg+0.5 mg+22.5 mg used for?
Ferrous Ascorbate + Folic Acid + Zinc Sulfate is indicated on prophylaxis of iron deficiency especially when inadequate diet calls for supplementary zinc and iron during pregnancy and anemia.
What is the dosage of Nuviron 48 mg+0.5 mg+22.5 mg?
Adult & Elderly: One tablet a day before or after meal (food independent absorption) or as directed by the physician. In more severe cases, two tablets a day may be required as prescribed by the physician. Pediatric patients: Safety and effectiveness in pediatric patients have not been established.
What are the side effects of Nuviron 48 mg+0.5 mg+22.5 mg?
Side effects of Ferrous Ascorbate + Folic Acid + Zinc Sulfate supplementation are mild and transient. These include epigastric pain, nausea, constipation, vomiting, diarrhoea, heart burn, etc. Allergic sensitization has been reported following both oral and parenteral administration of folic acid.
Who should not take Nuviron 48 mg+0.5 mg+22.5 mg?
Ferrous Ascorbate + Folic Acid + Zinc Sulfate is contraindicated in patients with haemolytic anaemia and in conditions with increased hypersensitivity to any of its components and increased body iron content.
What precautions should be taken with Nuviron 48 mg+0.5 mg+22.5 mg?
Care should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anemia or red cell aplasia. Failure to respond to treatment may indicate other causes of anemia and should be further investigated.
Is Nuviron 48 mg+0.5 mg+22.5 mg safe during pregnancy and breastfeeding?
If pregnant, or planning to become pregnant or are currently breast-feeding please contact your physician, before taking or continuing the drug. Administration in first trimester of pregnancy should be avoided unless definite evidence of iron deficiency is observed. Prophylaxis of iron deficiency is justified during the remainder of pregnancy specifically when zinc supplementation is required.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.