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Pedilid300 mg
Incepta Pharmaceuticals Ltd.
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Rolid300 mg
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Medicine overview
Indications of Rolid 300 mg
acute and chronic bronchitisand bronchopneumonia ENT infections like tonsillitispharyngitisacute and chronic bronchitisand bronchopneumonia ENT infections like tonsillitispharyngitissinusitis and otitis media. Skin infections like folliculitisfurunclescellulitiscarbunclespyodermaimpetigo and infected dermatitis. Genital infections like urethritisprostatitiscervicitis and salpingitis especially if produced by Chlamydia trachomatis.
Theropeutic Class
Macrolides
Pharmacology
Rolid 300 mg inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth.
Dosage & Administration of Rolid 300 mg
Adult dose
Dosage:The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days
Notes:Rolid 300 mg is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily
Pediatric dose
Dosage:The dose for children is 2.5 to 5 mg/kg body weight twice a day
Notes:The following general guidelines can be followed 6 to 11 Kg: 25 mg Rolid 300 mg 12 hourly. 12 to 23 Kg: 50 mg Rolid 300 mg 12 hourly. 24 to 40 Kg: 100 mg Rolid 300 mg 12 hourly. A normal course of therapy is between 5 and 10 days
| Condition | Dosage | Notes |
|---|---|---|
| Adult dose | The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days | Rolid 300 mg is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily |
| Pediatric dose | The dose for children is 2.5 to 5 mg/kg body weight twice a day | The following general guidelines can be followed 6 to 11 Kg: 25 mg Rolid 300 mg 12 hourly. 12 to 23 Kg: 50 mg Rolid 300 mg 12 hourly. 24 to 40 Kg: 100 mg Rolid 300 mg 12 hourly. A normal course of therapy is between 5 and 10 days |
Dosage of Rolid 300 mg
Adult dose
Dosage:The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days
Notes:Rolid 300 mg is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily
Pediatric dose
Dosage:The dose for children is 2.5 to 5 mg/kg body weight twice a day
Notes:The following general guidelines can be followed 6 to 11 Kg: 25 mg Rolid 300 mg 12 hourly. 12 to 23 Kg: 50 mg Rolid 300 mg 12 hourly. 24 to 40 Kg: 100 mg Rolid 300 mg 12 hourly. A normal course of therapy is between 5 and 10 days
| Condition | Dosage | Notes |
|---|---|---|
| Adult dose | The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days | Rolid 300 mg is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily |
| Pediatric dose | The dose for children is 2.5 to 5 mg/kg body weight twice a day | The following general guidelines can be followed 6 to 11 Kg: 25 mg Rolid 300 mg 12 hourly. 12 to 23 Kg: 50 mg Rolid 300 mg 12 hourly. 24 to 40 Kg: 100 mg Rolid 300 mg 12 hourly. A normal course of therapy is between 5 and 10 days |
Interaction of Rolid 300 mg
Rolid 300 mg does not have any affinity for cytochrome P-450 binding sites and thus is unlikely to produce drug interaction mediated by this enzymatic system. Rolid 300 mg shows mild interaction with theophylline though this has not been found to produce clinically relevant effects. Alteration in the pharmacokinetics of carbamazepine or warfarin has not been found. Antacids, H2- receptor antagonists and food has no effect on the absorption of Rolid 300 mg.
Contraindications
Rolid 300 mg should not be administered simultaneously with ergotamine or its derivatives as it may provoke arterial spasm and severe ischaemia.
Side Effects of Rolid 300 mg
Rolid 300 mg is well tolerated by patients of all age groups. Less than 4% of treated patients complain of side effects mainly nausea, abdominal pain, diarrhoea and hypersensitivity rash. Other side effects reported include vomiting, dizziness, headache, pruritus, dyspepsia, flatulence, tinnitus, vertigo and constipation. These are in general minor and do not necessitate withdrawal of therapy.
Pregnancy & Lactation
The safety of Rolid 300 mg in pregnancy has not been established. It appears in breast milk in small amounts and dose not produce adverse effects in the breast fed infant.
Precautions & Warnings
Rolid 300 mg should not be used in patients with a history of hypersensitivity to the drug. In patients with hepatic diseases the dose of Rolid 300 mg should not exceed 150 mg twice a day.
Drug Classes
Macrolides
Mode Of Action
Rolid 300 mg inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth.
Pregnancy
The safety of Rolid 300 mg in pregnancy has not been established. It appears in breast milk in small amounts and dose not produce adverse effects in the breast fed infant.
Frequently Asked Questions
What is Rolid 300 mg used for?
Roxithromycin is indicated in the treatment of infections caused by susceptible microorganisms- Respiratory infections like pneumonia, acute and chronic bronchitis, and bronchopneumonia ENT infections like tonsillitis, pharyngitis, sinusitis and otitis media. ... Read moreRoxithromycin is indicated in the treatment of infections caused by susceptible microorganisms- Respiratory infections like pne…
What is the dosage of Rolid 300 mg?
Adult dose: The usual dose for adults is one 300 mg tablet once daily or one 150 mg tablet twice a day for at least two days after resolution of symptoms, a normal course of therapy is between 5 and 10 days. Roxithromycin is best administered on empty stomach. In severe hepatic impairment the dose is 150 mg once daily.Pediatric dose: The dose for children is 2.5 to 5 mg/kg body weight twice a day.…
What are the side effects of Rolid 300 mg?
Roxithromycin is well tolerated by patients of all age groups. Less than 4% of treated patients complain of side effects mainly nausea, abdominal pain, diarrhoea and hypersensitivity rash. Other side effects reported include vomiting, dizziness, headache, pruritus, dyspepsia, flatulence, tinnitus, vertigo and constipation. These are in general minor and do not necessitate withdrawal of therapy.
Who should not take Rolid 300 mg?
Roxithromycin should not be administered simultaneously with ergotamine or its derivatives as it may provoke arterial spasm and severe ischaemia.
What precautions should be taken with Rolid 300 mg?
Roxithromycin should not be used in patients with a history of hypersensitivity to the drug. In patients with hepatic diseases the dose of Roxithromycin should not exceed 150 mg twice a day.
Is Rolid 300 mg safe during pregnancy and breastfeeding?
The safety of Roxithromycin in pregnancy has not been established. It appears in breast milk in small amounts and dose not produce adverse effects in the breast fed infant.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.