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Savlon

Savlon1.5%+15%

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Medicine overview

Indications of Savlon 1.5%+15%

For cleansing and irrigating the skin and dirty wounds where an added surfactant effect is required.

Theropeutic Class

Chlorhexidine & Chloroxylenol preparations

Pharmacology

Cetrimide is a quaternary ammonium antiseptic; it has bactericidal activity against both gram-positive and gram-negative organisms.

Absorption

Chlorhexidine is an antimicrobial agent; it is active against a wide range of gram-negative and grampositive vegetative bacteria, yeasts, dermatophyte fungi and lipophilic viruses.

Dosage & Administration of Savlon 1.5%+15%

Adult
Dosage:Topical per ml of liquid contains cetrimide 30 mg and chlorhexidine 3 mg: Use as directed

Dosage of Savlon 1.5%+15%

Notes:Rinse the area to be cleaned with water, apply the minimum amount of irrigation necessary to cover the wound area and wash gently. Rinse again thoroughly. Apply to wound as necessary. Discard remaining solution after use
Paediatric Use
Dosage:Use with care in neonates, particularly in premature infants
Notes:Chlorhexidine may cause irritation or chemical burns

Interaction of Savlon 1.5%+15%

There are no known drug interactions and none well documented.

Contraindications

Known hypersensitivity to either chlorhexidine or cetrimide. Do not use to irrigate the brain, meninges, eyes or perforated eardrum.

Side Effects of Savlon 1.5%+15%

Irritative skin reactions and hypersensitivity reactions to chlorhexidine have been reported. In the event that these reactions occur, discontinue use. Cetrimide may have a prolonging effect on the wound healing process.

Pregnancy & Lactation

Pregnancy Category-Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Precautions & Warnings

For external use only. Not for injection, for irrigation only. Not isotonic and is haemolytic. Cetrimide may have a prolonging effect on the wound healing process. Use of this antiseptic should be restricted to infection control and cleansing of wounds rather than general wound management.

Overdose Effects of Savlon 1.5%+15%

While accidental ingestion is unlikely to cause any systemic effects due to poor absorption of chlorhexidine and cetrimide, ingestion of high concentrations could cause irritation of the gastrointestinal mucosa/gastritis. Gastric lavage might be needed. Symptomatic treatment should be employed. If swallowed, wash out mouth, drink plenty of milk or water and seek medical advice. In case of overdose, seek medical attention or contact a poison control centre.

Storage Conditions

Store below 25°C. Protect from light. Single use only. Discard unused portion.

Drug Classes

Chlorhexidine & Chloroxylenol preparations

Mode Of Action

Chlorhexidine: Chlorhexidine is an antiseptic and disinfectant which is effective against a wide range of vegetative Gram-positive and Gram-negative organisms, some viruses and some fungi. It is ineffective against bacterial spores at room temperature, and acid-fast bacteria are inhibited but not killed. It is more active against Gram-positive than Gram-negative bacteria and some species of Pseudomonas and Proteus are relatively less susceptible. Chlorhexidine is most active at a neutral or slightly acid pH and its activity may be reduced by blood and other organic matter.Cetrimide: Cetrimide is a quaternary ammonium disinfectant with properties typical of cationic surfactants. Solutions of these surfactants have emulsifying and detergent properties and bactericidal activity against both Gram-positive and Gram-negative organisms but higher concentrations are necessary to kill the latter. The combined detergent and antibacterial properties of cetrimide make it useful in cleansing dirty or infected wounds. It is however, relatively ineffective against bacterial spores, acid-fast bacteria, viruses and fungi.

Pregnancy

Pregnancy: There are no adequate data from the use of chlorhexidine and cetrimide in pregnant women. The potential risk for humans is unknown but is most likely very low since chlorhexidine and cetrimide are poorly absorbed following topical application.Breastfeeding: It is not known whether chlorhexidine and cetrimide are excreted in breast milk. There are no adequate data from the use of chlorhexidine and cetrimide in breast-feeding women. However, it is unlikely that the products are excreted in breast milk, since the products are poorly absorbed. After topical usage of the product, as a general precaution, rinse nipples thoroughly with water before breastfeeding.

Frequently Asked Questions

What is Savlon 1.5%+15% used for?

For cleansing and irrigating the skin and dirty wounds where an added surfactant effect is required.

What is the dosage of Savlon 1.5%+15%?

Rinse the area to be cleaned with water, apply the minimum amount of irrigation necessary to cover the wound area and wash gently. Rinse again thoroughly. Apply to wound as necessary. Discard remaining solution after use.Paediatric Use: Use with care in neonates, particularly in premature infants. Chlorhexidine may cause irritation or chemical burns.

What are the side effects of Savlon 1.5%+15%?

Irritative skin reactions and hypersensitivity reactions to chlorhexidine have been reported. In the event that these reactions occur, discontinue use. Cetrimide may have a prolonging effect on the wound healing process.

Who should not take Savlon 1.5%+15%?

Known hypersensitivity to either chlorhexidine or cetrimide. Do not use to irrigate the brain, meninges, eyes or perforated eardrum.

What precautions should be taken with Savlon 1.5%+15%?

For external use only. Not for injection, for irrigation only. Not isotonic and is haemolytic. Cetrimide may have a prolonging effect on the wound healing process. Use of this antiseptic should be restricted to infection control and cleansing of wounds rather than general wound management.

Is Savlon 1.5%+15% safe during pregnancy and breastfeeding?

Pregnancy Category-Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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