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Tiagra5 mg
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Medicine overview
Indications of Tiagra 5 mg
Tiagra 5 mg is indicated in-
Erectile Dysfunction (ED)
Benign Prostatic Hyperplasia (BPH)
Both Erectile Dysfunction and signs and symptoms of Benign Prostatic Hyperplasia
Theropeutic Class
Drugs for Erectile Dysfunction
Pharmacology
Tiagra 5 mg is a selective phosphodiesterase type 5 (PDE5) inhibitor.
Absorption
Inhibition of PDE5 increases cGMP in smooth muscle cells.
Distribution
cGMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum, causing penile erection.
Metabolism
PDE5 also is present in smooth muscles of the prostate and bladder wall.
Excretion
Smooth muscle relaxation may improve blood flow to the urinary tract and widen the opening of the bladder neck, resulting in improved voiding.
Dosage & Administration of Tiagra 5 mg
Erectile Dysfunction
Dosage:For most patients the recommended starting dose is 10 mg
Notes:The dose may be increased to 20 mg or decreased to 5 mg based on requirement. The maximum dosing frequency is once daily. Tiagra 5 mg is effective for up to 36 hours
Benign prostatic hyperplasia
Dosage:The recommended dose is 5 mg taken at the same time every day
Notes:Combined Erectile Dysfunction and Benign prostatic hyperplasia: The recommended dose is 5 mg at the same time every day
| Condition | Dosage | Notes |
|---|---|---|
| Erectile Dysfunction | For most patients the recommended starting dose is 10 mg | The dose may be increased to 20 mg or decreased to 5 mg based on requirement. The maximum dosing frequency is once daily. Tiagra 5 mg is effective for up to 36 hours |
| Benign prostatic hyperplasia | The recommended dose is 5 mg taken at the same time every day | Combined Erectile Dysfunction and Benign prostatic hyperplasia: The recommended dose is 5 mg at the same time every day |
Dosage of Tiagra 5 mg
Erectile Dysfunction
Dosage:For most patients the recommended starting dose is 10 mg
Notes:The dose may be increased to 20 mg or decreased to 5 mg based on requirement. The maximum dosing frequency is once daily. Tiagra 5 mg is effective for up to 36 hours
Benign prostatic hyperplasia
Dosage:The recommended dose is 5 mg taken at the same time every day
Notes:Combined Erectile Dysfunction and Benign prostatic hyperplasia: The recommended dose is 5 mg at the same time every day
| Condition | Dosage | Notes |
|---|---|---|
| Erectile Dysfunction | For most patients the recommended starting dose is 10 mg | The dose may be increased to 20 mg or decreased to 5 mg based on requirement. The maximum dosing frequency is once daily. Tiagra 5 mg is effective for up to 36 hours |
| Benign prostatic hyperplasia | The recommended dose is 5 mg taken at the same time every day | Combined Erectile Dysfunction and Benign prostatic hyperplasia: The recommended dose is 5 mg at the same time every day |
Interaction of Tiagra 5 mg
May interact with Nitrates for example, Isosorbide, Nitroglycerin, Alpha adrenergic blockers, Antihypertensives, Alcohol, Antacids (magnesuim hydroxide/aluminum hydroxide), Ketoconazole, Ritonavir, Erythromycin, Itraconazole, Grapefruit juice, other HIV protease inhibitors, Rifampin, Carbamazepine, Phenytoin & Phenobarbital.
Contraindications
Use of Nitrates (for example, Nitroglycerine, Isosorbide): may increase hypotensive effects of Nitrates
Hypersensitivity reactions to Tiagra 5 mg
Side Effects of Tiagra 5 mg
Headache, Dyspepsia, Back pain, Myalgia, Nasal pharyngitis, Nasal congestion are common side effects. Change in Color Vision, Sudden vision loss, Hearing loss, Stevens-Johnson Syndrome, Exfoliative dermatitis, Angina, Stroke, Myocardial infarction, Severe hypotension, Tachycardia may also occur rarely.
Pregnancy & Lactation
Tiagra 5 mg has been assigned to pregnancy category B by the USFDA. Tiagra 5 mg is only recommended for use during pregnancy when benefit outweighs risk. There are no data on the excretion of Tiagra 5 mg in human milk. Caution should be used when administering Tiagra 5 mg to nursing women.
Precautions & Warnings
Angina, renal impairment, hepatic impairment, bleeding concomitant with Nitrates, Alpha Blockers, Alcohol, CYP3A4 Inhibitors (for example, Ritonavir, Ketoconazole, Itraconazole), other PDE5 inhibitors precaution should be taken in all these conditions.
Storage Conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Drug Classes
Drugs for Erectile Dysfunction
Mode Of Action
Tiagra 5 mg is a selective phosphodiesterase type 5 (PDE5) inhibitor. Inhibition of PDE5 increases cGMP in smooth muscle cells. cGMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum, causing penile erection. PDE5 also is present in smooth muscles of the prostate and bladder wall. Inhibiting PDE5 increases cGMP concentrations leading to relaxation of smooth muscle in the prostate and bladder. Smooth muscle relaxation may improve blood flow to the urinary tract and widen the opening of the bladder neck, resulting in improved voiding.
Pregnancy
Tiagra 5 mg has been assigned to pregnancy category B by the USFDA. Tiagra 5 mg is only recommended for use during pregnancy when benefit outweighs risk. There are no data on the excretion of Tiagra 5 mg in human milk. Caution should be used when administering Tiagra 5 mg to nursing women.
Frequently Asked Questions
What is Tiagra 5 mg used for?
Tadalafil is indicated in- Erectile Dysfunction (ED) Benign Prostatic Hyperplasia (BPH) Both Erectile Dysfunction and signs and symptoms of Benign Prostatic Hyperplasia
What is the dosage of Tiagra 5 mg?
Erectile Dysfunction: For most patients the recommended starting dose is 10 mg. The dose may be increased to 20 mg or decreased to 5 mg based on requirement. The maximum dosing frequency is once daily. Tadalafil is effective for up to 36 hours.Benign prostatic hyperplasia: The recommended dose is 5 mg taken at the same time every day.Combined Erectile Dysfunction and Benign prostatic hyperplasia: …
What are the side effects of Tiagra 5 mg?
Headache, Dyspepsia, Back pain, Myalgia, Nasal pharyngitis, Nasal congestion are common side effects. Change in Color Vision, Sudden vision loss, Hearing loss, Stevens-Johnson Syndrome, Exfoliative dermatitis, Angina, Stroke, Myocardial infarction, Severe hypotension, Tachycardia may also occur rarely.
Who should not take Tiagra 5 mg?
Use of Nitrates (for example, Nitroglycerine, Isosorbide): may increase hypotensive effects of Nitrates Hypersensitivity reactions to Tadalafil
What precautions should be taken with Tiagra 5 mg?
Angina, renal impairment, hepatic impairment, bleeding concomitant with Nitrates, Alpha Blockers, Alcohol, CYP3A4 Inhibitors (for example, Ritonavir, Ketoconazole, Itraconazole), other PDE5 inhibitors precaution should be taken in all these conditions.
Is Tiagra 5 mg safe during pregnancy and breastfeeding?
Tadalafil has been assigned to pregnancy category B by the USFDA. Tadalafil is only recommended for use during pregnancy when benefit outweighs risk. There are no data on the excretion of Tadalafil in human milk. Caution should be used when administering tadalafil to nursing women.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.