Tussidex

Tussidex100 ml

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Medicine overview

Indications of Tussidex 100 ml

Dextromethorphan is indicated in Chronic dry cough or unproductive coughAcute dry cough which is interfering with normal function or sleep.

Theropeutic Class

Cough suppressant

Pharmacology

Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain.

Absorption

Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center.

Distribution

This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker.

Metabolism

It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Dosage & Administration of Tussidex 100 ml

Adults and Children over 12 years
Dosage:15 to 30 mg three to four times per day
Notes:However, 60 mg doses up to four times per day have been used without increased side effects
Children between 6 and 12 years
Dosage:5-15 mg up to four times per day
Children between 2 and 6 years
Dosage:2.5-5 mg up to four times per day

Dosage of Tussidex 100 ml

Adults and Children over 12 years
Dosage:15 to 30 mg three to four times per day
Notes:However, 60 mg doses up to four times per day have been used without increased side effects
Children between 6 and 12 years
Dosage:5-15 mg up to four times per day
Children between 2 and 6 years
Dosage:2.5-5 mg up to four times per day

Interaction of Tussidex 100 ml

The following medicines should be taken carefully while concomitantly use with Dextromethorphan: Amiodarone, Fluoexetine, Quinidine, CNS depressants and Monoamine oxidase (MAO) inhibitors.

Contraindications

Hypersensitivity to Dextromethorphan or any other component.

Side Effects of Tussidex 100 ml

Adverse effects with Dextromethorphan are rare, but nausea and dizziness sometimes occur. The drug produces no analgesia or addiction and little or no CNS depression. Excitation, confusion and respiratory depression may occur after overdosage.

Pregnancy & Lactation

Pregnancy: Adequate and well-controlled studies in human have not been done. However, Dextromethorphan has not been reported to cause birth defects. Lactation: It is not known whether dextromethorphan passes into breast milk. However, Dextromethorphan has not been reported to cause problems in nursing babies.

Precautions & Warnings

Do not use Dextromethorphan to control a cough that is associated with smoking, asthma, or emphysema, or a cough that is productive (produces sputum or phlegm).

Overdose Effects of Tussidex 100 ml

Symptoms: In mild overdose, tachycardia, hypertension, vomiting, mydriasis, diaphoresis, nystagmus, euphoria, loss of motor coordination, and giggling; in moderate intoxication, in addition to those listed above, hallucinations and a plodding ataxic gait; in severely intoxication, agitation or somnolence. Management: treatment is symptomatic and supportive. Naloxone may be useful in reversing toxicity.

Storage Conditions

Store at 15-30° C

Drug Classes

Cough suppressant

Mode Of Action

Dextromethorphan suppresses the cough reflex by a direct action on the cough center in the medulla of the brain. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Pregnancy

Pregnancy: Adequate and well-controlled studies in human have not been done. However, Dextromethorphan has not been reported to cause birth defects. Lactation: It is not known whether dextromethorphan passes into breast milk. However, Dextromethorphan has not been reported to cause problems in nursing babies.

Frequently Asked Questions

What is Tussidex 100 ml used for?

Dextromethorphan is indicated in Chronic dry cough or unproductive cough; Acute dry cough which is interfering with normal function or sleep.

What is the dosage of Tussidex 100 ml?

Adults and Children over 12 years: 15 to 30 mg three to four times per day. However, 60 mg doses up to four times per day have been used without increased side effects.Children between 6 and 12 years: 5-15 mg up to four times per day.Children between 2 and 6 years: 2.5-5 mg up to four times per day.

What are the side effects of Tussidex 100 ml?

Adverse effects with Dextromethorphan are rare, but nausea and dizziness sometimes occur. The drug produces no analgesia or addiction and little or no CNS depression. Excitation, confusion and respiratory depression may occur after overdosage.

Who should not take Tussidex 100 ml?

Hypersensitivity to Dextromethorphan or any other component.

What precautions should be taken with Tussidex 100 ml?

Do not use Dextromethorphan to control a cough that is associated with smoking, asthma, or emphysema, or a cough that is productive (produces sputum or phlegm).

Is Tussidex 100 ml safe during pregnancy and breastfeeding?

Pregnancy: Adequate and well-controlled studies in human have not been done. However, Dextromethorphan has not been reported to cause birth defects. Lactation: It is not known whether dextromethorphan passes into breast milk. However, Dextromethorphan has not been reported to cause problems in nursing babies.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.