Vidalin N

Vidalin N is a parenteral (intravenous) preparation used to provide supplemental vitamins together with isotonic fluid and electrolyte support to patients who cannot meet their nutritional or fluid requirements by the oral route.

Established/Guideline-Supported Uses

• Short-term parenteral supplementation of water- and fat-soluble vitamins in patients who are nil by mouth, post-operative, critically ill, or unable to tolerate oral/enteral nutrition.
• Maintenance or replacement of fluid and electrolytes (via the normal saline component) in patients with mild dehydration or fluid deficit who also require vitamin supplementation.
• Adjunctive support in malnourished or chronically ill patients (e.g., prolonged hospitalization, alcohol use disorder, malabsorption syndromes) as part of a broader nutritional care plan.

Adjunct/Combination-Therapy Use

• Used as an adjunct to total parenteral nutrition (TPN) or other IV fluid regimens rather than as a substitute for complete nutritional therapy.

Vidalin N is not intended to replace a balanced oral diet once oral or enteral intake is possible, and is not indicated for the routine treatment of specific vitamin-deficiency diseases requiring targeted, higher-dose vitamin therapy.

Multivitamin and Normal Saline combines a multivitamin preparation (a mixture of water-soluble vitamins such as vitamin C and B-complex vitamins, and/or fat-soluble vitamins such as vitamins A, D, E, and K, depending on the specific formulation) with 0.9% sodium chloride (Normal Saline) as the intravenous diluent/vehicle.

The exact vitamin content and concentration of sodium chloride solution used for Multivitamin and Normal Saline may vary by manufacturer and product strength; the prescribing physician determines the specific formulation and volume appropriate for each patient.

Vidalin N is a sterile, ready-to-administer intravenous infusion in which a multivitamin concentrate is diluted in isotonic (0.9%) sodium chloride solution. It is designed for infusion via a peripheral or central intravenous line under the supervision of a healthcare professional.

By combining vitamin supplementation with an isotonic fluid vehicle, Vidalin N allows simultaneous correction of mild fluid deficits and provision of essential vitamins in a single infusion, which is useful in hospitalized patients with limited oral intake.

Vidalin N belongs to the therapeutic class of parenteral vitamin/nutritional supplements combined with intravenous electrolyte (isotonic saline) solutions.

The multivitamin component of Multivitamin and Normal Saline acts by replenishing water- and fat-soluble vitamins that function as essential cofactors in carbohydrate, protein, and fat metabolism, antioxidant defense, and various enzymatic reactions. When administered intravenously, these vitamins bypass gastrointestinal absorption, achieving direct systemic availability, which is useful when oral absorption is unreliable or impossible.

The normal saline component (0.9% sodium chloride) is an isotonic crystalloid solution that expands extracellular fluid volume and supplies sodium and chloride ions, helping to maintain fluid and electrolyte balance without causing significant fluid shifts between intracellular and extracellular compartments.

• Vidalin N is for intravenous infusion only and must not be given by intramuscular, subcutaneous, or oral routes.
• Administer using aseptic technique through a properly placed peripheral or central venous line.
• Inspect the solution visually for particulate matter or discoloration before use; do not use if the solution is cloudy, discolored, or contains visible particles.
• Infuse at the rate specified by the treating physician, and monitor the patient for infusion-site reactions, fluid overload, and hypersensitivity during and after administration.

Vidalin N should be used cautiously with other intravenous fluids or medications administered concurrently through the same line, as incompatibilities can occur; consult a pharmacist regarding Y-site compatibility before co-infusing other drugs.

• Corticosteroids/mineralocorticoids: concurrent use with the sodium chloride component of Vidalin N may increase the risk of sodium and fluid retention.
• Lithium: changes in sodium intake from the saline component of Vidalin N can alter lithium excretion and blood levels; monitor lithium levels closely if co-administered.
• Anticoagulants (e.g., warfarin): fat-soluble vitamin components (if present, such as vitamin K) in Vidalin N may reduce the anticoagulant effect; monitor coagulation status.

Most reported reactions to Vidalin N relate to the infusion itself or to individual vitamin components.

• Common: infusion-site pain, redness, or phlebitis; mild nausea.
• Less common: fluid overload symptoms (swelling, shortness of breath) if infused too rapidly or in excessive volume; flushing (associated with certain B vitamins).
• Rare but serious: hypersensitivity/allergic reactions, including anaphylaxis (see Contraindications and Precautions); electrolyte disturbances with prolonged or excessive use.

Vidalin N should be used in pregnancy only if clearly needed and if the potential benefit justifies the potential risk to the fetus; use only under the direct guidance and supervision of a physician when parenteral vitamin/fluid supplementation is clinically indicated.

Similarly, use during breastfeeding should occur only under medical supervision, weighing the clinical need for parenteral supplementation against any potential risk to the nursing infant. Consult a physician before use in pregnancy or lactation.

• Vidalin N must be administered only by, or under direct supervision of, a healthcare professional with appropriate intravenous access; it is not for self-administration.
• Monitor fluid balance, serum electrolytes, and signs of fluid overload closely, particularly in patients with cardiac, renal, or hepatic impairment, and in elderly patients.
• Observe the infusion site regularly for signs of extravasation, phlebitis, or infection.
• Use with caution in patients with uncontrolled hypertension, as the sodium chloride component may worsen fluid retention and blood pressure control if not properly monitored.
• Discontinue immediately and seek medical attention if signs of hypersensitivity (rash, itching, swelling, difficulty breathing) occur during infusion.

Overdose of Vidalin N may present as symptoms of fluid overload (edema, shortness of breath, hypertension) from excessive sodium chloride volume, and/or symptoms related to excess intake of specific vitamin components (which vary by formulation).

If overdose is suspected, stop the infusion immediately and seek immediate medical attention or contact emergency services/a poison control center. Treatment is supportive and should be managed by a healthcare professional; do not attempt home management of a suspected overdose.

Store at room temperature (below 30°C), away from light and moisture. Keep out of reach of children. Do not use if the container is damaged or the solution shows discoloration or particulate matter.

Elderly

Use Vidalin N with caution in elderly patients, who are more susceptible to fluid overload and electrolyte disturbances; monitor fluid status closely.

Renal Impairment

Use with caution; individualize fluid volume and vitamin dosing under physician supervision (see Dosage and Administration).

Hepatic Impairment

Use with caution, particularly regarding fat-soluble vitamin components; individualize under physician supervision.

Pediatric Population

See Pediatric Uses.

The duration of treatment with Vidalin N is determined by the treating physician based on the patient's clinical status, and is generally continued only until the patient can resume adequate oral or enteral intake of fluids and vitamins. Prolonged use should be reassessed regularly by the physician.

Multivitamin and Normal Saline is classified as a parenteral multivitamin/nutritional supplement in combination with an intravenous isotonic electrolyte (crystalloid) solution.

Multivitamin and Normal Saline works through two combined mechanisms: the multivitamin component replenishes essential water- and fat-soluble vitamin cofactors required for normal metabolic and enzymatic function, while the normal saline component restores extracellular fluid volume and supplies sodium and chloride to help maintain fluid and electrolyte homeostasis.

Use of Vidalin N in pediatric patients should be individualized by a pediatrician, with dosing and infusion volume adjusted according to the child's weight, age, and clinical condition. Safety and efficacy of specific fixed-dose combination formulations of Vidalin N have not been separately established in all pediatric age groups; use only under close pediatric medical supervision.