
Virux-HC5%+1%
Square Pharmaceuticals PLC.
Acyclovir + Hydrocortisone topical cream is a combination antiviral-corticosteroid preparation with an established indication: Early treatment of recurrent herpes labialis (cold sores) in adults and…
Acyclovir + Hydrocortisone topical cream is a combination antiviral-corticosteroid preparation with an established indication:
Acyclovir + Hydrocortisone has not been shown to be effective when initiated after the cold sore has developed to the papule, vesicle, or ulcerative stage, and it has not been shown to prevent recurrences or transmission of herpes simplex virus. It is not indicated for use inside the mouth, in the eyes, on the genitals, or for other forms of herpes infection.
| Indication | Population | Dose |
|---|---|---|
| Herpes labialis (cold sores), early treatment | Adults and children ≥ 6 years | Apply a thin layer of Acyclovir + Hydrocortisone cream to the affected area 5 times daily for 5 days |
Treatment with Acyclovir + Hydrocortisone should be started as early as possible, ideally during the prodromal stage (tingling, itching, burning, or redness) before any visible lesion appears, for the best chance of reducing lesion progression. If a course of Acyclovir + Hydrocortisone is not started until after the cold sore has already developed into a blister or ulcer, benefit is less certain.
Safety and efficacy of Acyclovir + Hydrocortisone for repeated, intermittent, or chronic use beyond a single 5-day course have not been established; see Precautions and Warnings regarding prolonged corticosteroid exposure.
Most reported side effects with Acyclovir + Hydrocortisone are limited to the application site and are usually mild:
Systemic side effects are rare with correctly used topical Acyclovir + Hydrocortisone because absorption through skin is minimal. Discontinue and seek medical advice if signs of an allergic reaction (rash, swelling of the face/lips/tongue, difficulty breathing) occur.
Acyclovir + Hydrocortisone is contraindicated in patients with known hypersensitivity to acyclovir, valacyclovir, hydrocortisone, or any other component of the cream formulation.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.