Calcium Dobesilate + Lidocaine HCl + Dexamethasone Acetate: Brands, Price & Uses in Bangladesh

Calcium Dobesilate + Lidocaine HCl + Dexamethasone Acetate is a fixed-dose combination topical/rectal preparation (vasoprotective agent + local anesthetic + corticosteroid) used for anorectal conditions. Its use is classified below by strength of evidence:

• Established/labeled use: Symptomatic relief of internal and external hemorrhoids (piles) and associated anal conditions (pruritus ani, minor anal fissures, proctitis) - reduces pain, itching, swelling, and vascular fragility/bleeding tendency of the hemorrhoidal tissue. Intended for short-term symptomatic use.
• Adjunct use: May be used as an adjunct to conservative measures (dietary fiber, stool softeners, sitz baths) in the overall management of hemorrhoidal disease; it does not treat the underlying cause and is not a substitute for surgical management when indicated.
• Off-label/physician-directed use: Short-term symptomatic relief after minor anorectal procedures may be used off-label under medical supervision; this is not an FDA/DGDA-labeled indication and should only be used as directed by a physician.

Calcium Dobesilate + Lidocaine HCl + Dexamethasone Acetate does not treat the underlying vascular or structural cause of hemorrhoidal disease and should not be used to self-treat rectal bleeding of unknown cause (see Precautions and Warnings).

Calcium Dobesilate + Lidocaine HCl + Dexamethasone Acetate is intended for external/topical and intra-rectal use only, for short-term symptomatic treatment of hemorrhoids and related anorectal conditions.

Pediatric dosing is not established (see Use in Special Populations). No well-established renal or hepatic dose-adjustment schedule exists for this topical/rectal combination because systemic exposure is normally minimal; however, caution and medical supervision are advised in patients with significant hepatic impairment because systemically absorbed lidocaine is hepatically metabolized.

Hands should be washed before and after application; the applicator tip (if any) should not be inserted deeply into the rectum. Do not exceed the recommended dose, frequency, or duration of use.

Local adverse effects are most common with Calcium Dobesilate + Lidocaine HCl + Dexamethasone Acetate; systemic effects are uncommon with recommended short-term use but can occur with overuse or extensive application.

• Common (local): Local burning, stinging, or itching at the application site; local irritation or mild erythema.
• Less common: Local hypersensitivity/allergic contact reactions (rash, contact dermatitis); with prolonged use, local skin/mucosal thinning (atrophy), telangiectasia, or delayed local healing due to the corticosteroid component.
• Rare (usually with excessive/overuse or absorption through broken mucosa): Systemic lidocaine toxicity signs (dizziness, perioral numbness, tinnitus, drowsiness, and rarely seizures or cardiac arrhythmia); systemic corticosteroid effects (e.g., adrenal suppression) with extensive or prolonged use.

Discontinue use and seek medical advice if a rash, worsening irritation, or any signs of systemic toxicity develop.