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Desloratadine + Pseudoephedrine: Brands, Price & Uses in Bangladesh
Desloratadine + Pseudoephedrine is an established, approved combination indicated for the symptomatic relief of seasonal allergic rhinitis (hay fever) in patients whose symptoms include nasal…
About Desloratadine + Pseudoephedrine
Indications of Desloratadine + Pseudoephedrine
Desloratadine + Pseudoephedrine is an established, approved combination indicated for the symptomatic relief of seasonal allergic rhinitis (hay fever) in patients whose symptoms include nasal congestion in addition to the classic antihistamine-responsive symptoms.
Established / approved use
- Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis — sneezing, rhinorrhea, itchy/watery eyes, itchy nose or throat — together with nasal congestion, in adults and adolescents 12 years of age and older.
Uses requiring the combination specifically
Desloratadine + Pseudoephedrine is intended only for patients who have both allergy symptoms (addressed by the desloratadine component) and nasal congestion (addressed by the pseudoephedrine component). Patients with allergy symptoms but no congestion should use desloratadine alone, and patients with congestion only should use a decongestant alone.
Not established
Desloratadine + Pseudoephedrine has not been shown to be effective for perennial (year-round) allergic rhinitis, the common cold, sinusitis, or non-allergic rhinitis, and is not indicated for children under 12 years of age.
Dosage & Administration of Desloratadine + Pseudoephedrine
Dosage by indication
| Population | Indication | Recommended dose |
|---|---|---|
| Adults and adolescents ≥ 12 years | Seasonal allergic rhinitis with nasal congestion | One tablet of Desloratadine + Pseudoephedrine taken orally twice daily, approximately 12 hours apart |
| Children under 12 years | Not applicable | Desloratadine + Pseudoephedrine is not recommended; safety and efficacy have not been established |
Administration instructions
- Tablets of Desloratadine + Pseudoephedrine should be swallowed whole with water; do not crush, split, or chew the tablet, as this destroys the extended-release mechanism.
- May be taken with or without food.
- Use the lowest effective duration needed to control symptoms (see Duration of Treatment).
Renal or hepatic impairment
Because Desloratadine + Pseudoephedrine is a fixed-dose combination tablet, its dose cannot be individually titrated. In patients with significant renal or hepatic impairment who require a lower desloratadine dose, or in the elderly, a physician should consider using the individual component drugs separately instead of Desloratadine + Pseudoephedrine so the dose of each can be adjusted appropriately.
Side Effects of Desloratadine + Pseudoephedrine
The most commonly reported side effects of Desloratadine + Pseudoephedrine (occurring in roughly 2% or more of patients) include:
- Insomnia / difficulty sleeping
- Headache
- Dry mouth
- Fatigue and somnolence
- Dizziness
- Nausea
- Sore throat (pharyngitis)
- Decreased appetite
Less common but more serious effects can include palpitations, tachycardia, elevated blood pressure, tremor, nervousness, and, rarely, hypersensitivity reactions (rash, angioedema, difficulty breathing) — see Precautions and Warnings and Overdose Effects for related safety information.
Contraindications of Desloratadine + Pseudoephedrine
Desloratadine + Pseudoephedrine is contraindicated in the following situations:
- Known hypersensitivity to desloratadine, pseudoephedrine, loratadine, or any excipient of Desloratadine + Pseudoephedrine.
- Current use of a monoamine oxidase inhibitor (MAOI), or use of an MAOI within the preceding 14 days, due to the risk of hypertensive crisis.
- Severe hypertension or severe coronary artery disease.
- Narrow-angle (angle-closure) glaucoma.
- Urinary retention.
Frequently Asked Questions about Desloratadine + Pseudoephedrine
What is Desloratadine + Pseudoephedrine used for?
Desloratadine + Pseudoephedrine is used to relieve the symptoms of seasonal allergic rhinitis (hay fever) — including sneezing, runny nose, itchy or watery eyes — together with nasal congestion, in adults and adolescents 12 years of age and older.
How should I take Desloratadine + Pseudoephedrine?
Take one tablet of Desloratadine + Pseudoephedrine by mouth twice daily, about 12 hours apart, swallowed whole with water. Do not crush or chew the tablet. It can be taken with or without food.
Can I take Desloratadine + Pseudoephedrine if I have high blood pressure or heart disease?
Desloratadine + Pseudoephedrine is contraindicated in people with severe hypertension or severe coronary artery disease because the decongestant component can raise blood pressure and heart rate. If you have any cardiovascular condition, consult your physician before using Desloratadine + Pseudoephedrine.
Is Desloratadine + Pseudoephedrine safe during pregnancy or breastfeeding?
Desloratadine + Pseudoephedrine should be used in pregnancy only if clearly needed, since the potential benefit must be weighed against potential risk to the fetus. Both components pass into breast milk, and the decongestant may reduce milk supply, so breastfeeding mothers should consult a physician before using Desloratadine + Pseudoephedrine.
Can children take Desloratadine + Pseudoephedrine?
No. Desloratadine + Pseudoephedrine is not recommended for children under 12 years of age because safety and efficacy have not been established in this age group.
What should I do if I take too much Desloratadine + Pseudoephedrine?
An overdose of Desloratadine + Pseudoephedrine can cause a rapid heartbeat, very high blood pressure, severe restlessness, tremor, or seizures. Seek immediate medical attention or contact a poison control center or emergency services right away if an overdose of Desloratadine + Pseudoephedrine is suspected.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.