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Elagox150 mg
Nuvista Pharma Ltd.
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Generic medicine
Elagolix: Brands, Price & Uses in Bangladesh
Elagolix is an oral gonadotropin-releasing hormone (GnRH) antagonist indicated for the following use: FDA-approved/established use: Management of moderate to severe pain associated with…
About Elagolix
Indications of Elagolix
Elagolix is an oral gonadotropin-releasing hormone (GnRH) antagonist indicated for the following use:
- FDA-approved/established use: Management of moderate to severe pain associated with endometriosis in adult women of reproductive age.
Elagolix is not approved or indicated for use in men, in pediatric patients, as a contraceptive, or for any condition other than endometriosis-associated pain.
Dosage & Administration of Elagolix
Dosing of Elagolix depends on treatment duration and use of other medications:
| Regimen | Dose | Maximum Duration |
|---|---|---|
| Standard dose | 150 mg orally once daily | Up to 24 months |
| Higher dose (more severe pain) | 200 mg orally twice daily | Up to 6 months |
Elagolix should be taken at approximately the same time each day, with or without food, swallowed whole with water, and initiated within the first 5 days of the onset of menses.
See Duration of Treatment and Use in Special Populations for dose adjustment in hepatic impairment.
Side Effects of Elagolix
Common side effects reported with Elagolix include:
- Hot flashes/flushes
- Headache
- Nausea
- Insomnia and mood changes, including anxiety
- Amenorrhea and menstrual irregularities
- Arthralgia
- Changes in cholesterol/lipid levels
See Precautions and Warnings for information on bone mineral density (BMD) loss associated with Elagolix.
Contraindications of Elagolix
Elagolix is contraindicated in:
- Known hypersensitivity to Elagolix or any component of the formulation.
- Pregnancy.
- Known osteoporosis.
- Severe hepatic impairment.
- Concomitant use with strong OATP1B1 inhibitors (e.g., cyclosporine, gemfibrozil).
Frequently Asked Questions about Elagolix
What is Elagolix used for?
Elagolix is used to manage moderate to severe pain associated with endometriosis in adult women.
How should I take Elagolix?
Take Elagolix exactly as prescribed, at the same time each day, with or without food, swallowing the tablet whole with water. Do not stop or change your dose without consulting your physician.
Can Elagolix be used during pregnancy?
No. Elagolix is contraindicated during pregnancy because it may cause fetal harm, including bone-related risks. Pregnancy should be excluded before starting treatment, and a non-hormonal contraceptive method should be used during therapy.
What is the most important safety concern with Elagolix?
Elagolix can cause a dose- and duration-dependent loss of bone mineral density, which may not be fully reversible. For this reason, treatment duration is limited to up to 24 months at the lower dose or up to 6 months at the higher dose, and your physician may monitor your bone health.
Can I take hormonal birth control with Elagolix?
Elagolix may reduce the effectiveness of combined hormonal contraceptives, so a non-hormonal contraceptive method is generally recommended during treatment unless your physician directs otherwise.
Is Elagolix safe for children?
Elagolix is not approved for use in children or adolescents under 18 years of age; safety and efficacy have not been established in this population.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.