10% Off
Herplex0.1%
Opso Saline Ltd.
৳54.18
Out Of Stock
Generic medicine
Idoxuridine: Brands, Price & Uses in Bangladesh
Idoxuridine is a topical antiviral agent indicated for the treatment of herpes simplex keratitis (dendritic corneal ulcers) caused by herpes simplex virus infection of the eye.
About Idoxuridine
Indications of Idoxuridine
Idoxuridine is a topical antiviral agent indicated for the treatment of herpes simplex keratitis (dendritic corneal ulcers) caused by herpes simplex virus infection of the eye.
- Established/approved use: Epithelial (dendritic) herpes simplex keratitis, where Idoxuridine acts on actively replicating virus within infected corneal epithelial cells.
- Limited/adjunctive use: Idoxuridine has limited efficacy in deep stromal herpetic keratitis when there is no epithelial (dendritic) involvement, and is generally not used alone in that setting.
- Not indicated for bacterial, fungal, or other viral eye infections; Idoxuridine has no proven benefit outside herpes simplex epithelial keratitis, and unnecessary use should be avoided.
Dosage & Administration of Idoxuridine
| Indication | Population | Recommended Dosing |
|---|---|---|
| Herpes simplex (dendritic) keratitis | Adults | Instill 1 drop of Idoxuridine 0.1% ophthalmic solution into the affected eye(s) every 1 hour during the day and every 2 hours at night until definite improvement occurs (usually within 3-5 days); then reduce to every 2 hours during the day and every 4 hours at night. |
| Herpes simplex (dendritic) keratitis | Children | Use only under direct ophthalmologist supervision; safety and efficacy of specific pediatric dosing regimens are not well established (see Use in Special Populations). |
Treatment is typically continued for 3-5 days after complete healing of the corneal lesion is confirmed by an ophthalmologist, and total treatment is generally not continued beyond approximately 21 days due to the risk of corneal toxicity. Idoxuridine must be administered only under ophthalmologist supervision, with regular eye examinations to monitor response and detect toxicity.
Idoxuridine is for topical ophthalmic use only and must not be injected or taken by mouth.
Side Effects of Idoxuridine
Side effects of Idoxuridine are generally local, affecting the eye:
- Local irritation, burning, stinging, or itching of the eye
- Photophobia (sensitivity to light)
- Pain in or around the eye
- Allergic reactions such as eyelid swelling (edema), redness, or follicular conjunctivitis
- Punctate defects of the corneal epithelium
- With prolonged use: corneal clouding, small stromal opacities, or delayed corneal wound healing
Patients should notify their physician promptly if irritation worsens, if vision changes occur, or if the eye condition does not improve as expected.
Contraindications of Idoxuridine
Idoxuridine is contraindicated in patients with known hypersensitivity to Idoxuridine or any component of the formulation.
Frequently Asked Questions about Idoxuridine
What is Idoxuridine used for?
Idoxuridine is a topical antiviral eye medication used to treat herpes simplex keratitis (dendritic corneal ulcers), a corneal infection caused by the herpes simplex virus.
How should I use Idoxuridine eye drops?
Instill the prescribed number of drops of Idoxuridine into the affected eye at the exact frequency prescribed by your ophthalmologist (often hourly during the day and every 2 hours at night initially), without touching the dropper tip to the eye, and continue for the full duration prescribed even as symptoms improve.
Can I use Idoxuridine for any red or infected eye?
No. Idoxuridine is only effective against herpes simplex virus infections of the corneal epithelium (dendritic ulcers). It is not effective against bacterial, fungal, or other viral eye infections, so a proper diagnosis by an eye specialist is essential before starting Idoxuridine.
Is Idoxuridine safe to use during pregnancy?
Idoxuridine has minimal systemic absorption when used topically in the eye, but there are no well-controlled studies in pregnant women. It should be used during pregnancy only if clearly needed and if the potential benefit justifies the potential risk to the fetus, and only under a physician's direction.
What side effects can Idoxuridine cause?
Idoxuridine may cause local eye irritation, burning, stinging, sensitivity to light, eyelid swelling, or allergic conjunctivitis. Prolonged use can cause corneal clouding or punctate defects, so regular follow-up with an ophthalmologist is important during treatment.
Can I use steroid eye drops together with Idoxuridine?
Topical corticosteroids should generally be avoided during active herpes simplex keratitis treated with Idoxuridine, as they can worsen or mask the infection and increase the risk of corneal complications. Only use a steroid eye drop together with Idoxuridine if specifically directed by your ophthalmologist.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.