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Acliz50 mg
Aristopharma Ltd.
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Generic medicine
Meclizine Hydrochloride: Brands, Price & Uses in Bangladesh
Meclizine Hydrochloride is a first-generation antihistamine (piperazine derivative) with established antiemetic and anti-vertigo activity.
About Meclizine Hydrochloride
Indications of Meclizine Hydrochloride
Meclizine Hydrochloride is a first-generation antihistamine (piperazine derivative) with established antiemetic and anti-vertigo activity. Its indications are classified below by strength of evidence:
Established/Approved Uses
- Vertigo: Management of vertigo associated with diseases affecting the vestibular system in adults.
- Motion sickness: Prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness (an established over-the-counter use in many markets).
Adjunct/Symptomatic Use
- Symptomatic relief of nausea and vomiting of various causes as an adjunct, used only under medical supervision when the underlying cause has been assessed by a physician.
Meclizine Hydrochloride does not treat the underlying cause of vertigo or motion sickness; it only relieves associated symptoms.
Dosage & Administration of Meclizine Hydrochloride
Motion Sickness (Prevention)
Adults and adolescents (12 years and older): 25–50 mg taken orally approximately 1 hour before travel. May be repeated every 24 hours for the duration of the journey, as directed by a physician.
Vertigo
Adults: 25–100 mg per day, given in divided doses, depending on clinical response, as prescribed by a physician.
| Indication | Typical Adult Dose | Notes |
|---|---|---|
| Motion sickness | 25–50 mg once, 1 hour before travel | May repeat every 24 hours if needed |
| Vertigo | 25–100 mg/day in divided doses | Titrate to lowest effective dose |
Tablets should be swallowed whole with water, or chewable tablets chewed thoroughly, as per the product formulation. Meclizine Hydrochloride should always be taken exactly as directed by the prescribing physician or as per product labeling for over-the-counter use.
Side Effects of Meclizine Hydrochloride
The most commonly reported adverse effect of Meclizine Hydrochloride is drowsiness, which may impair the ability to drive or operate machinery, especially when combined with alcohol or other CNS depressants.
Common Side Effects
- Drowsiness/sedation (most common)
- Dry mouth
- Blurred vision
- Headache
- Fatigue
Less Common/Rare Side Effects
- Urinary retention (anticholinergic effect)
- Constipation
- Tachycardia
- Hypersensitivity/allergic reactions, including rare anaphylactic reactions
Contraindications of Meclizine Hydrochloride
Meclizine Hydrochloride is contraindicated in patients with known hypersensitivity to meclizine or any component of the formulation.
Frequently Asked Questions about Meclizine Hydrochloride
What is Meclizine Hydrochloride used for?
Meclizine Hydrochloride is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness, and to manage vertigo associated with disorders of the vestibular (inner ear balance) system.
Can Meclizine Hydrochloride make me drowsy?
Yes, drowsiness is the most common side effect of Meclizine Hydrochloride. You should avoid driving or operating heavy machinery until you know how it affects you, and avoid alcohol while taking it.
Is Meclizine Hydrochloride safe during pregnancy?
Meclizine Hydrochloride should be used during pregnancy only if clearly needed and if the potential benefit justifies the potential risk to the fetus. Always consult your physician before using it if you are pregnant.
Can children take Meclizine Hydrochloride?
Meclizine Hydrochloride is generally not recommended for children under 12 years old because safety and efficacy have not been established in this age group. It should only be given to older children/adolescents under medical guidance.
What should I do if I miss a dose or take too much Meclizine Hydrochloride?
If you miss a dose used on an as-needed basis, simply take it when next needed as directed. If you suspect an overdose (symptoms like extreme drowsiness, confusion, or blurred vision), seek immediate medical attention or contact a poison control center right away.
Can I take Meclizine Hydrochloride with other medicines?
Meclizine Hydrochloride can interact with alcohol, sedatives, and other CNS depressants, increasing drowsiness. Always inform your physician or pharmacist of all medicines you are taking before starting Meclizine Hydrochloride.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.