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Mometasone Furoate: Brands, Price & Uses in Bangladesh
Mometasone Furoate is a synthetic corticosteroid used topically, intranasally, and by oral inhalation depending on the formulation.
About Mometasone Furoate
Indications of Mometasone Furoate
Mometasone Furoate is a synthetic corticosteroid used topically, intranasally, and by oral inhalation depending on the formulation. Its approved and guideline-supported uses include:
Topical (cream, ointment, lotion) - FDA-approved
- Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, including atopic dermatitis (eczema), psoriasis, and other forms of dermatitis, in patients 2 years of age and older.
Intranasal (nasal spray) - FDA-approved
- Prophylaxis and treatment of nasal symptoms of seasonal and perennial allergic rhinitis in adults and children (age limits vary by product, generally 2 years and older for OTC formulations and 12 years and older for prescription strength).
- Treatment of chronic rhinosinusitis with nasal polyps in adults 18 years of age and older.
Oral inhalation (dry powder inhaler) - FDA-approved
- Maintenance treatment of asthma as prophylactic therapy in patients 4 years of age and older, including patients who require systemic corticosteroid therapy, where it also helps reduce or eliminate the need for oral corticosteroids.
Mometasone Furoate inhaled and intranasal forms are for maintenance/prophylactic use only and are not intended to relieve acute bronchospasm or acute nasal symptoms.
Dosage & Administration of Mometasone Furoate
Topical (cream/ointment/lotion 0.1%)
| Population | Dose |
|---|---|
| Adults and children ≥2 years | Apply a thin film to the affected skin area once daily; discontinue when control is achieved |
Intranasal (nasal spray, 50 mcg/spray)
| Indication | Population | Dose |
|---|---|---|
| Allergic rhinitis | Adults and children ≥12 years | 2 sprays in each nostril once daily (200 mcg/day total) |
| Allergic rhinitis (OTC products) | Children 2-11 years | 1 spray in each nostril once daily under adult supervision |
| Chronic rhinosinusitis with nasal polyps | Adults ≥18 years | 2 sprays in each nostril twice daily (up to 400 mcg/day); some patients may respond to once-daily dosing |
Oral inhalation (dry powder inhaler, 110/220 mcg per actuation)
| Population | Prior therapy | Starting dose |
|---|---|---|
| Adults and adolescents ≥12 years | Previously on bronchodilators alone or inhaled corticosteroids | 220 mcg once daily in the evening (up to 220 mcg twice daily in more severe disease) |
| Adults and adolescents ≥12 years | Previously on oral corticosteroids | 220 mcg twice daily |
| Children 4-11 years | Allergic asthma | 110 mcg once daily in the evening |
Rinse the mouth after each inhaled dose without swallowing to reduce the risk of oral candidiasis. Shake nasal spray before use; prime the pump before first use or after periods of non-use per product labeling. Mometasone Furoate inhaler and nasal spray are not intended for relief of acute symptoms; a fast-acting bronchodilator should be used for acute asthma symptoms, not the inhaled form of Mometasone Furoate.
Side Effects of Mometasone Furoate
Topical use
- Burning, stinging, itching, or irritation at the application site
- Skin atrophy, striae, and telangiectasia with prolonged or inappropriate use (e.g., under occlusion, on the face, or in skin folds)
- Folliculitis, acneiform eruptions, hypopigmentation (uncommon)
Intranasal use
- Headache
- Nasal irritation, burning, or dryness
- Epistaxis (nosebleed)
- Pharyngitis, viral upper respiratory infection, cough
- Rarely: nasal septal perforation, impaired wound healing
Inhaled use
- Oropharyngeal (oral) candidiasis - reduce risk by rinsing the mouth with water after each dose
- Hoarseness (dysphonia) and throat irritation
- Headache, upper respiratory infection
- Growth suppression has been reported in children on long-term, high-dose inhaled corticosteroid therapy; monitor growth periodically
Systemic corticosteroid effects (e.g., adrenal suppression, Cushingoid features) are rare with Mometasone Furoate at recommended doses but may occur with excessive or prolonged use, especially in combination with other corticosteroid sources.
Contraindications of Mometasone Furoate
Mometasone Furoate is contraindicated in patients with known hypersensitivity to mometasone furoate or to any component of the specific formulation.
The inhaled form is contraindicated for the primary treatment of status asthmaticus or other acute episodes of asthma requiring intensive measures, as it is not a bronchodilator and has no role in relieving acute bronchospasm.
Frequently Asked Questions about Mometasone Furoate
What conditions is Mometasone Furoate used for?
Depending on the formulation, Mometasone Furoate is used topically for inflammatory skin conditions such as eczema, psoriasis, and dermatitis; as a nasal spray for allergic rhinitis and nasal polyps; and as an inhaler for the long-term maintenance treatment of asthma.
Can Mometasone Furoate be used to treat a sudden asthma attack?
No. The inhaled form of Mometasone Furoate is a maintenance medication only and does not relieve acute bronchospasm. A separate fast-acting rescue inhaler should be used for sudden asthma symptoms, and a physician should be consulted if rescue inhaler use increases.
Is it safe to use Mometasone Furoate during pregnancy or while breastfeeding?
Mometasone Furoate should be used during pregnancy or breastfeeding only if clearly needed and if the potential benefit justifies the potential risk to the fetus or infant, at the lowest effective dose, and only under a physician's guidance, as safety data in humans are limited.
What are the common side effects of Mometasone Furoate?
Common side effects vary by formulation and include local irritation, burning, or stinging at the application site; headache and nosebleeds with nasal spray use; and oral thrush (candidiasis) or hoarseness with inhaler use. Rinsing the mouth after inhaler use reduces the risk of oral thrush.
Can I stop using Mometasone Furoate suddenly?
Long-term or high-dose use of Mometasone Furoate should not be stopped abruptly without medical advice, as this may unmask underlying adrenal suppression; any change in dose or discontinuation should be guided by a physician, especially after prolonged use.
Who should not use Mometasone Furoate?
Mometasone Furoate should not be used by anyone with a known hypersensitivity to mometasone furoate or to any ingredient in the specific product, and the inhaled form should not be used to treat acute asthma attacks or status asthmaticus.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.