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Compressed breathing oxygen
Linde Bangladesh Ltd.
৳22006.80
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Oxygen: Brands, Price & Uses in Bangladesh
Oxygen is a medical gas used by inhalation to treat and prevent hypoxemia (low blood oxygen levels).
About Oxygen
Indications of Oxygen
Oxygen is a medical gas used by inhalation to treat and prevent hypoxemia (low blood oxygen levels). Its uses are classified below by strength of evidence.
Established / Guideline-Supported Uses
- Acute hypoxemia from any cause, including respiratory failure, acute exacerbation of chronic obstructive pulmonary disease (COPD), pneumonia, asthma exacerbation, and acute respiratory distress syndrome (ARDS), guided by pulse oximetry or arterial blood gas measurement.
- Long-term oxygen therapy (LTOT) for chronic hypoxemic conditions (e.g., severe COPD) that meet established criteria (resting arterial oxygen pressure or saturation below guideline thresholds), shown to improve survival in qualifying patients.
- Perioperative and anesthesia-related use, including during surgery, procedural sedation, and post-anesthesia recovery.
- Cardiac and circulatory conditions associated with hypoxemia, such as acute heart failure or shock with documented low oxygen saturation.
- Carbon monoxide poisoning, where high-concentration Oxygen accelerates displacement of carbon monoxide from hemoglobin.
- Neonatal resuscitation and neonatal respiratory distress, titrated carefully to target saturation ranges.
- Acute mountain sickness / high-altitude hypoxia as supportive therapy.
Adjunct / Symptomatic Use
- Short-term symptomatic relief of dyspnea in palliative care when hypoxemia is documented.
- High-flow Oxygen as an adjunct in the acute treatment of cluster headache attacks.
Oxygen should be administered based on physician assessment, typically guided by pulse oximetry or blood gas monitoring, and titrated to the lowest flow/concentration that achieves the target oxygen saturation for the patient's condition.
Dosage & Administration of Oxygen
Oxygen dosing is expressed as flow rate (liters per minute) or fraction of inspired oxygen (FiO2) and must be individualized and titrated to a target oxygen saturation using pulse oximetry or arterial blood gas monitoring, per physician assessment.
| Indication | Typical Adult Dosing/Target | Pediatric Dosing |
|---|---|---|
| Acute hypoxemia (general) | Nasal cannula 1-6 L/min or mask as needed; titrate to SpO2 94-98% | Titrate to age-appropriate SpO2 target under physician supervision |
| COPD with risk of hypercapnia | Controlled low-flow/Venturi delivery; titrate to SpO2 88-92% | Not typically applicable |
| Carbon monoxide poisoning | High-concentration Oxygen via non-rebreather mask (as close to 100% as possible) until carboxyhemoglobin normalizes | Same principle; dose per pediatric specialist |
| Long-term oxygen therapy (chronic hypoxemia) | Continuous or nocturnal flow individually titrated (commonly 1-4 L/min) to maintain SpO2 above 90%, reassessed periodically | Individualized under pediatric pulmonology care |
| Neonatal use | Not applicable | Carefully titrated FiO2 to target SpO2 (commonly 90-95% in preterm infants) to avoid hyperoxia |
No renal or hepatic dose adjustment is required, as Oxygen is not metabolized by the liver or kidneys.
Side Effects of Oxygen
Adverse effects of Oxygen are generally related to excessive concentration or duration of exposure (hyperoxia) rather than the gas itself at appropriate therapeutic levels.
- Oxygen toxicity: Prolonged exposure to high FiO2 (generally above 60%) can cause substernal chest discomfort, cough, tracheobronchitis, and, with extended exposure, lung injury resembling ARDS.
- Absorption atelectasis: High-concentration Oxygen can cause collapse of poorly ventilated alveoli.
- Airway dryness/irritation: Unhumidified Oxygen, especially at higher flows, can dry and irritate the nasal and airway mucosa, occasionally causing nosebleeds.
- Retinopathy of prematurity: Excessive Oxygen in preterm infants increases the risk of this eye condition (see Use in Special Populations).
- CNS oxygen toxicity (seizures): Rare with standard low-pressure (normobaric) Oxygen therapy; more relevant to hyperbaric oxygen use.
Contraindications of Oxygen
There are no true absolute contraindications to Oxygen therapy when hypoxemia is present and correction is clinically indicated, since Oxygen is a physiologic gas rather than a pharmaceutical compound with allergenic potential. Administration should nonetheless be avoided in situations where excessive Oxygen (hyperoxia) is known to cause harm without clear indication, such as routine high-concentration use in paraquat poisoning (see Interactions) — this is a caution rather than an absolute contraindication.
Frequently Asked Questions about Oxygen
What is Oxygen used for?
Oxygen is used to treat and prevent hypoxemia (low blood oxygen levels) in conditions such as COPD exacerbation, pneumonia, respiratory failure, ARDS, carbon monoxide poisoning, during surgery/anesthesia, and for long-term therapy in chronic hypoxemic conditions. It is administered by inhalation and titrated to a target oxygen saturation.
How is Oxygen dosed?
Oxygen is not dosed in milligrams but by flow rate (liters per minute) or fraction of inspired oxygen (FiO2), individualized to each patient and titrated using pulse oximetry or blood gas monitoring to reach a target saturation, as determined by the treating physician.
Is Oxygen safe during pregnancy?
Oxygen is used in pregnancy when the mother has documented or suspected hypoxemia and is generally considered acceptable when clinically needed, using the lowest effective concentration; a physician should be consulted regarding the specific condition being treated.
Can too much Oxygen be harmful?
Yes. Excessive or prolonged high-concentration Oxygen (hyperoxia) can cause oxygen toxicity, lung irritation, absorption atelectasis, and in preterm infants, retinopathy of prematurity. In some patients with chronic hypercapnic respiratory failure, uncontrolled high-flow Oxygen can also worsen carbon dioxide retention, so flow/concentration should always be titrated and monitored by a physician.
What safety precautions are needed when using Oxygen at home?
Because Oxygen supports combustion, it should be kept away from open flame, sparks, smoking, and oil or grease-based products. Cylinders should be stored upright and secured in a well-ventilated area away from heat, and all Oxygen equipment should be kept out of reach of children.
Are there any drug interactions with Oxygen?
Oxygen has few interactions since it is not systemically metabolized, but high-concentration Oxygen can increase the risk of lung toxicity in patients previously treated with bleomycin, and can worsen lung injury in paraquat poisoning; your physician will adjust Oxygen use accordingly in these situations.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.