10% Off
Mygest100 mg
Drug International Ltd.
৳135.00
Add to cart
Generic medicine
Progesterone Micronized: Brands, Price & Uses in Bangladesh
Progesterone Micronized is a natural progestin hormone used for the following indications: Established / Approved Uses Secondary amenorrhea: Used to induce a withdrawal bleed in women with secondary…
About Progesterone Micronized
Indications of Progesterone Micronized
Progesterone Micronized is a natural progestin hormone used for the following indications:
Established / Approved Uses
- Secondary amenorrhea: Used to induce a withdrawal bleed in women with secondary amenorrhea due to inadequate endogenous progesterone production.
- Prevention of endometrial hyperplasia: Given cyclically with estrogen replacement therapy in non-hysterectomized postmenopausal women receiving estrogen, to oppose estrogen's stimulatory effect on the endometrium.
Guideline-Supported / Adjunct Uses
- Luteal phase support in assisted reproductive technology (ART): Used as part of combination protocols during in-vitro fertilization (IVF) and other ART cycles to support the endometrial lining and early pregnancy, typically alongside other fertility medications and under specialist supervision.
- Hormone replacement therapy (HRT): Used in combination with estrogen for relief of moderate-to-severe vasomotor (menopausal) symptoms in women with an intact uterus.
Vaginal and topical formulations of Progesterone Micronized may have additional or different approved uses (e.g., threatened/recurrent miscarriage support in some countries); consult product-specific labeling and a physician.
Dosage & Administration of Progesterone Micronized
Dosing of Progesterone Micronized is individualized based on indication, route of administration, and clinical response. See "Dosage" for indication-specific doses and "Administration" for route-specific instructions. A summary is provided below.
| Indication | Typical Adult Dose | Duration |
|---|---|---|
| Secondary amenorrhea | 400 mg orally once daily at bedtime for 10 days | One treatment course; may be repeated cyclically as directed |
| Endometrial hyperplasia prevention (with estrogen HRT) | 200 mg orally once daily at bedtime for 12 consecutive days per 28-day cycle | Cyclic, ongoing with estrogen therapy |
| Luteal phase support (ART/IVF) | Variable (commonly 200-800 mg/day in divided doses, oral, vaginal, or injectable, per fertility protocol) | Per ART protocol, as directed by fertility specialist |
Always follow the exact regimen prescribed by the treating physician, as protocols vary by indication, formulation, and individual response.
Side Effects of Progesterone Micronized
Common side effects of Progesterone Micronized include:
- Drowsiness, dizziness, or fatigue (especially within a few hours of oral dosing)
- Headache
- Breast tenderness or swelling
- Bloating, abdominal cramping
- Mood changes, irritability, or depression
- Nausea
- Vaginal spotting or irregular bleeding
- Joint pain
Less common but serious effects include venous thromboembolism (see Precautions), severe allergic reaction, and jaundice. Seek prompt medical attention for chest pain, shortness of breath, leg swelling/pain, sudden vision changes, or signs of an allergic reaction.
Contraindications of Progesterone Micronized
Progesterone Micronized is contraindicated in patients with any of the following:
- Known hypersensitivity to progesterone or any component of the formulation, including peanut oil (many oral micronized progesterone products use peanut oil as a carrier) — contraindicated in patients with peanut allergy.
- Undiagnosed abnormal vaginal bleeding.
- Known, suspected, or history of breast cancer or other known or suspected progestin-sensitive cancer.
- Active deep vein thrombosis, pulmonary embolism, or history of these conditions.
- Active arterial thromboembolic disease (e.g., stroke, myocardial infarction) or history of these conditions.
- Active liver disease or hepatic tumors.
- Known or suspected pregnancy, except for indications where Progesterone Micronized is specifically used to support the luteal phase or early pregnancy in ART, which must be directed by a specialist.
- Porphyria.
Frequently Asked Questions about Progesterone Micronized
What is Progesterone Micronized used for?
Progesterone Micronized is used to treat secondary amenorrhea (absent periods), to support the luteal phase during fertility treatments such as IVF, and, combined with estrogen, to protect the uterine lining during menopausal hormone replacement therapy.
When should I take Progesterone Micronized?
Progesterone Micronized is usually taken at bedtime because it commonly causes drowsiness and dizziness within a few hours of dosing; taking it at night reduces the impact of this side effect on daily activities.
Can I take Progesterone Micronized if I am allergic to peanuts?
Many oral capsules of Progesterone Micronized are formulated using peanut oil as a carrier. If you have a peanut allergy, tell your physician before starting Progesterone Micronized, as an alternative formulation may be needed.
Is Progesterone Micronized safe during pregnancy?
Progesterone Micronized is used under specialist supervision for luteal phase and early pregnancy support in fertility treatment. For other indications, it is contraindicated in known or suspected pregnancy. Outside of specialist-directed fertility care, it should be used in pregnancy only if clearly needed and if the benefit justifies the potential risk to the fetus, and only after consulting a physician.
What are the serious risks of Progesterone Micronized?
The most important serious risk of Progesterone Micronized is an increased chance of blood clots (venous thromboembolism), especially when combined with estrogen. Other serious but less common risks include severe allergic reaction (especially in peanut-allergic patients), liver problems, and mood changes such as depression. Seek immediate medical attention for chest pain, leg swelling, shortness of breath, or signs of an allergic reaction.
What should I do if I miss a dose or take too much Progesterone Micronized?
If you miss a dose of Progesterone Micronized, take it as soon as you remember unless it is nearly time for the next dose. If you or someone else has taken too much Progesterone Micronized, seek immediate medical attention or contact a poison control center.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.