Pyridoxine Hydrochloride: Brands, Price & Uses in Bangladesh

Pyridoxine Hydrochloride is a form of vitamin B6 used for the following indications:

Established/FDA-approved uses

• Prevention and treatment of vitamin B6 (pyridoxine) deficiency, including deficiency caused by poor diet, malabsorption, alcohol use disorder, or certain medications.
• Prevention and treatment of isoniazid-induced peripheral neuropathy in patients receiving isoniazid therapy for tuberculosis.
• Treatment of pyridoxine-dependent seizures, a rare inherited metabolic disorder that presents in infancy.

Guideline-supported / adjunct uses

• Sideroblastic anemia that is pyridoxine-responsive, usually as an adjunct with other therapy.
• Nausea and vomiting of pregnancy, often used alone or in combination with doxylamine succinate under medical supervision.

Commonly used off-label

• Symptomatic relief of premenstrual syndrome (PMS), though evidence is limited and it should be used under medical guidance.

Pyridoxine Hydrochloride is not a treatment for conditions unrelated to vitamin B6 deficiency or the specific indications listed above.

Dosage of Pyridoxine Hydrochloride depends on the indication being treated. See the Dosage section for indication-specific dosing and the Administration section for how to take it.

Pyridoxine Hydrochloride is generally well tolerated at standard supplemental and therapeutic doses. Reported side effects include:

• Mild nausea or stomach upset
• Headache
• Drowsiness or tingling sensations (paresthesia), usually mild and transient at recommended doses

With chronic high-dose use (see Precautions and Warnings for details), sensory peripheral neuropathy, unsteady gait, and numbness of the hands and feet have been reported, which may be irreversible in severe cases. Rare hypersensitivity reactions have also been reported.