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Simethicone: Brands, Price & Uses in Bangladesh
Established / Approved Uses Simethicone is indicated for the symptomatic relief of excess gas (flatulence) associated with conditions such as functional dyspepsia, air swallowing (aerophagia) and more.
About Simethicone
Indications of Simethicone
Established / Approved Uses
- Simethicone is indicated for the symptomatic relief of excess gas (flatulence) associated with conditions such as functional dyspepsia, air swallowing (aerophagia), postoperative gas pain, and diverticular disease.
- Relief of pressure, bloating, and fullness commonly referred to as "gas" in adults and children.
Adjunct / Procedural Uses
- Used as an adjunct before abdominal ultrasound, endoscopy, or radiologic imaging to reduce interfering intestinal gas bubbles and improve visualization.
Commonly Used Off-Label
- Simethicone drops are widely used for infant colic and excessive crying attributed to gas, although clinical trial evidence for efficacy in colic is limited and inconsistent. It remains popular for this use mainly because of its excellent safety profile rather than proven efficacy.
Simethicone does not treat underlying digestive or bowel conditions; if gas symptoms are due to another disease process, that condition must be evaluated and managed separately by a physician.
Dosage & Administration of Simethicone
Adults and Children 12 years and older
| Indication | Dose | Frequency |
|---|---|---|
| Gas, bloating, postprandial fullness | 40–125 mg (up to 250 mg with some products) | After meals and at bedtime as needed; do not exceed 500 mg in 24 hours unless directed by a physician |
Children 2 to under 12 years
| Age | Dose | Frequency |
|---|---|---|
| 2–12 years | 40 mg | Four times daily as needed after meals and at bedtime; do not exceed 240 mg in 24 hours unless directed by a physician |
Infants under 2 years
| Age | Dose | Frequency |
|---|---|---|
| Under 2 years | 20 mg (0.3 mL of infant drops) | Four times daily as needed; do not exceed 240 mg in 24 hours; use only under medical/caregiver guidance |
Procedural / Diagnostic Use
When used as an adjunct before abdominal imaging, dosing and timing are determined by the ordering physician or facility protocol.
Administration
- Chewable tablets must be chewed thoroughly before swallowing, not swallowed whole.
- Softgel capsules should be swallowed whole with liquid.
- Infant drops may be given directly or mixed with 1 ounce (30 mL) of cool water, infant formula, or other liquid to ease administration; shake the suspension well before use.
- Best taken after meals and at bedtime, when gas symptoms are most likely to occur.
Side Effects of Simethicone
Simethicone is very well tolerated overall, consistent with its non-absorbed, purely physical mechanism of action. Reported adverse effects are uncommon and generally mild.
- Mild gastrointestinal effects: nausea, belching, or diarrhea have been reported infrequently.
- Rare hypersensitivity reactions: skin rash or itching (see Contraindications for hypersensitivity).
No serious systemic adverse effects have been reported, reflecting the fact that Simethicone is not absorbed into the bloodstream.
Contraindications of Simethicone
Simethicone is contraindicated only in patients with known hypersensitivity to Simethicone or to any component of the specific product formulation.
Frequently Asked Questions about Simethicone
What is Simethicone used for?
Simethicone is used to relieve the discomfort of excess gas, bloating, and fullness in the stomach and intestines. It is also sometimes used before abdominal ultrasound or endoscopy to reduce gas interference, and is commonly used off-label for infant gas-related fussiness.
Is Simethicone safe to take every day?
Simethicone is generally very well tolerated because it is not absorbed into the bloodstream and works only by physical action in the gut. It can be used as needed after meals and at bedtime, but if you need it daily for more than 2 weeks, consult a physician to check for an underlying cause of your gas symptoms.
Can Simethicone be given to infants and young children?
Yes, specially formulated Simethicone drops are made for infants and children, with dosing based on age. However, Simethicone is not absorbed systemically and its efficacy for infant colic specifically is not firmly proven; use under caregiver or physician guidance and seek medical advice if crying is severe or persistent.
Is Simethicone safe during pregnancy or breastfeeding?
Simethicone is not absorbed from the gut, so it is generally considered compatible with pregnancy and breastfeeding. Even so, it should be used only if clearly needed, and a physician should be consulted before regular use during pregnancy or while breastfeeding.
Does Simethicone interact with other medicines?
Simethicone has minimal interaction potential because it is not absorbed into the bloodstream and acts only locally in the gastrointestinal tract. No clinically significant drug interactions are well established, though you should still tell your doctor or pharmacist about all medicines you take.
What should I do if I take too much Simethicone?
Simethicone has very low toxicity due to its lack of systemic absorption, so a simple overdose of Simethicone alone is unlikely to cause serious harm. Still, if a large amount was taken, especially of a combination product, or if unusual symptoms occur, seek immediate medical attention or contact a poison control center.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.