Sodium Feredetate Trihydrate: Brands, Price & Uses in Bangladesh

Sodium Feredetate Trihydrate is an oral iron replacement therapy indicated for:

• Established use: Treatment of iron-deficiency anemia in adults, children, and infants, including cases where conventional ferrous iron salts (e.g., ferrous sulfate) are poorly tolerated due to gastrointestinal side effects.
• Established use: Prevention (prophylaxis) of iron-deficiency anemia in at-risk groups, including low-birth-weight infants, young children, and pregnant women, under medical supervision.
• Guideline-supported adjunct use: Iron-deficiency anemia occurring in pregnancy, particularly when standard oral iron formulations cause intolerable gastrointestinal upset.
• Adjunct use: Anemia secondary to chronic inflammatory conditions such as rheumatoid arthritis, where iron deficiency has been confirmed, used alongside treatment of the underlying disease.

Sodium Feredetate Trihydrate is not indicated for anemias not caused by iron deficiency (e.g., hemolytic anemia, anemia of chronic disease without confirmed iron deficiency, or megaloblastic anemia due to vitamin B12/folate deficiency).

The dose of Sodium Feredetate Trihydrate should be individualized based on age, body weight, severity of iron deficiency, and indication (treatment vs. prevention). The information below reflects typical oral solution dosing; always follow the prescribing physician's instructions and the specific product label.

No well-established dose adjustment is required for renal or hepatic impairment; however, Sodium Feredetate Trihydrate should be used cautiously in patients with hepatic disease due to the risk of iron accumulation (see Precautions and Warnings). Absorption of Sodium Feredetate Trihydrate may be reduced by antacids, proton pump inhibitors, or tetracycline-class antibiotics taken at the same time; see Interactions for dosing-timing advice.

Most side effects of Sodium Feredetate Trihydrate are gastrointestinal and generally milder than with conventional ferrous iron salts, though they can still occur:

• Nausea
• Mild diarrhea or, less commonly, constipation
• Abdominal discomfort
• Dark or black-colored stools (a harmless but expected effect of unabsorbed iron)
• Rarely, hypersensitivity reactions (skin rash, itching)

If severe abdominal pain, persistent vomiting, black tarry stools accompanied by dizziness, or signs of an allergic reaction (swelling, difficulty breathing) occur while taking Sodium Feredetate Trihydrate, seek medical attention promptly.