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Tadalafil: Brands, Price & Uses in Bangladesh
Erectile Dysfunction (ED) Tadalafil is FDA-approved for the treatment of erectile dysfunction, used either on an as-needed basis before anticipated sexual activity or as a once-daily regimen.
About Tadalafil
Indications of Tadalafil
Erectile Dysfunction (ED)
Tadalafil is FDA-approved for the treatment of erectile dysfunction, used either on an as-needed basis before anticipated sexual activity or as a once-daily regimen.
Benign Prostatic Hyperplasia (BPH)
Tadalafil is FDA-approved for the treatment of the signs and symptoms of benign prostatic hyperplasia, and is also approved for the combined treatment of ED and BPH signs and symptoms when both conditions are present, using a once-daily regimen.
Pulmonary Arterial Hypertension (PAH)
Tadalafil is FDA-approved for the treatment of pulmonary arterial hypertension (WHO Group 1) to improve exercise ability, using a separate formulation/strength and dosing schedule than the ED and BPH indications.
Dosage & Administration of Tadalafil
Dosing of Tadalafil differs substantially by indication (erectile dysfunction, benign prostatic hyperplasia, or pulmonary arterial hypertension) and by whether an on-demand or once-daily regimen is used; the exact starting dose, maximum dose, and dosing interval must be individualized by a physician. Tadalafil for pulmonary arterial hypertension uses a different total daily dose than the ED/BPH tablets and is not interchangeable with them without medical guidance.
Side Effects of Tadalafil
Common Side Effects
- Headache
- Indigestion (dyspepsia)
- Back pain and muscle aches (myalgia), typically delayed in onset and self-limited
- Flushing
- Nasal congestion
- Pain in the arms or legs
Serious Side Effects (Seek Medical Attention)
- Sudden decrease or loss of vision in one or both eyes (possible non-arteritic anterior ischemic optic neuropathy) - stop taking Tadalafil and seek immediate medical attention (see Precautions and Warnings).
- Sudden decrease or loss of hearing, sometimes with ringing in the ears or dizziness - stop taking Tadalafil and seek medical attention.
- An erection lasting longer than 4 hours (priapism) - seek immediate medical attention to prevent permanent damage.
- Chest pain, dizziness, or fainting during sexual activity, which may indicate a cardiovascular event (see Precautions and Warnings).
- Signs of a severe allergic reaction: rash, hives, swelling of the face/lips/tongue/throat, or difficulty breathing.
Contraindications of Tadalafil
- Concomitant use with any form of organic nitrates (regularly or intermittently), due to the risk of severe, potentially fatal hypotension.
- Concomitant use with guanylate cyclase (GC) stimulators, such as riociguat, due to the risk of symptomatic hypotension.
- Known hypersensitivity to Tadalafil or any component of the formulation.
Frequently Asked Questions about Tadalafil
What is Tadalafil used for?
Tadalafil is used to treat erectile dysfunction, the urinary symptoms of an enlarged prostate (benign prostatic hyperplasia), and pulmonary arterial hypertension. The dose and regimen differ depending on which condition is being treated.
How long does Tadalafil last, and how is it different from other ED medicines?
Tadalafil has a notably longer duration of action than other PDE5 inhibitors, with effects that can last up to 36 hours after an on-demand dose, which is why it is sometimes called a "weekend pill." It can also be taken as a lower once-daily dose for continuous effect rather than timed around sexual activity.
Can I take Tadalafil with nitrate medicines (e.g., for chest pain)?
No. Tadalafil must never be combined with any form of nitrate medicine (such as nitroglycerin) or with guanylate cyclase stimulators like riociguat, because the combination can cause a sudden, severe, and potentially fatal drop in blood pressure. Always tell any doctor or emergency personnel that you take Tadalafil.
What should I do if I get an erection lasting more than 4 hours?
An erection lasting longer than 4 hours (priapism) is a medical emergency. Seek immediate medical attention, as prolonged priapism can cause permanent damage to the penis if not treated promptly.
Can Tadalafil cause vision or hearing problems?
Rarely, Tadalafil and other PDE5 inhibitors have been associated with sudden vision loss (due to a condition called non-arteritic anterior ischemic optic neuropathy) or sudden hearing loss. If either occurs, stop taking Tadalafil and seek immediate medical attention.
Is it safe to drink alcohol while taking Tadalafil?
Drinking a large amount of alcohol while taking Tadalafil may increase the risk of dizziness, low blood pressure, or a fast heartbeat when standing up. Moderate alcohol use should be discussed with your doctor.
Disclaimer
The information provided is accurate to the best of our knowledge, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy, and the absence of specific information about a drug should not be taken as an endorsement. We are not responsible for any consequences arising from this information, so please consult a healthcare professional for any concerns or questions.