Adinir 300 mg is indicated for the treatment of Community Acquired Pneumonia, Acute Exacerbation of Chronic Bronchitis, Acute Maxillary Sinusitis, Pharyngitis, Tonsillitis, Uncomplicated Skin and Skin Structure, Infections

Theropeutic Class

Third generation Cephalosporins

Pharmacology

Adinir 300 mg binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Dosage & Administration of Adinir 300 mg

Adult: 600 mg daily as a single or in 2 divided doses for 5-10 days.Child: ≥6 months: 14 mg/kg daily as a single or in 2 divided doses. Max: 600 mg daily.

Dosage of Adinir 300 mg

Adult: 600 mg daily as a single or in 2 divided doses for 5-10 days.Child: ≥6 months: 14 mg/kg daily as a single or in 2 divided doses. Max: 600 mg daily.

Interaction of Adinir 300 mg

Antacids: Adinir 300 mg should be taken at least 2 hours interval of antacid administration.Iron supplement: Adinir 300 mg should be taken at least 2 hours interval of iron supplement administration.Probencid: It inhibits the renal excretion of Adinir 300 mg.

Contraindications

Adinir 300 mg is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.

Side Effects of Adinir 300 mg

Common side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.

Pregnancy & Lactation

Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Following administration of single 600 mg doses, Adinir 300 mg was not detected in human breast milk.

Precautions & Warnings

Adinir 300 mg, as with other broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis. In patients with transient or persistent renal insufficiency (creatinine clearance <30 ml/min), the total daily dose of Adinir 300 mg should be reduced.

Overdose Effects of Adinir 300 mg

Symptoms: Nausea, vomiting, epigastric distress, diarrhoea, convulsions. Management: Haemodialysis may be useful in the event of a serious toxic reaction particularly if renal function is compromised.

Storage Conditions

Store between 20-25° C.

Drug Classes

Third generation Cephalosporins

Mode Of Action

Pregnancy

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.