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Aventy100 mg

Name: Aventy 100 mg
Brand: Aventy
Price: 285.00 BDT
Availability: InStock

Tablet

~~MRP ৳ 300.00~~5% Off

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Medicine overview

Indications of Aventy 100 mg

Aventy 100 mg is a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction

Theropeutic Class

Drugs for Erectile Dysfunction

Pharmacology

Aventy 100 mg is a selective phosphodiesterase 5 (PDE5) enzyme inhibitor used for the treatment of erectile dysfunction caused by diabetes, age induced oxidative stress or other complications.

Absorption

Aventy 100 mg inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis.

Distribution

This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells.

Metabolism

Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum.

Excretion

Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle.

Dosage & Administration of Aventy 100 mg

For most patients, the starting dose is 100 mg taken approximately 30 minutes before sexual activity, on an as needed basis. Aventy 100 mg may be taken with or without food. Take Aventy 100 mg no more than once a dayThe dose may be increased to 200 mg or decreased to 50 mg based on efficacy and/or tolerability. Use the lowest dose that provides benefitDo not use Aventy 100 mg with strong CYP3A4 inhibitors. If taking a moderate CYP3A4 inhibitor, the dose should be no more than 50 mg in a 24-hour period. In patients on stable alpha-blocker therapy, the recommended starting dose of Aventy 100 mg is 50 mg

Dosage of Aventy 100 mg

Interaction of Aventy 100 mg

Aventy—100 mg can potentiate the hypotensive effect of nitrates, alphablockers, antihypertensives, and alcohol

CYP—3A4 inhibitors (e

, ketoconazole, ritonavir, erythromycin) increase Aventy 100 mg exposure

Contraindications

Administration of Aventy 100 mg to patients using any form of organic nitrate is contraindicated. Hypersensitivity to any component of the Aventy 100 mg tablet

Side Effects of Aventy 100 mg

Common (>1%)

Most common adverse reactions (greater than or equal to 2%) include headache
flushing

Uncommon

nasal congestion
nasopharyngitis

Rare / Long-term

and back pain

Pregnancy & Lactation

Pregnancy Category C. Aventy 100 mg is not indicated for use in women. There are no adequate and well-controlled studies of Aventy 100 mg in pregnant women.

Precautions & Warnings

Patients should not use Aventy 100 mg if sexual activity is inadvisable due to cardiovascular status or any other reason Use of Aventy 100 mg with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotensionPatients should seek emergency treatment if an erection lasts greater than 4 hoursPatients should stop Aventy 100 mg and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of Non Arteritic Ischemic Optic Neuropathy (NAION). Discuss with patients the increased risk of NAION in patients with a history of NAIONPatients should stop taking Aventy 100 mg and seek prompt medical attention in the event of sudden decrease or loss of hearing

Overdose Effects of Aventy 100 mg

Single doses up to 800 mg have been given to healthy subjects, and multiple doses up to 300 mg have been given to patients. In cases of overdose, standard supportive measures should be adopted as required. Renal dialysis is not expected to accelerate clearance because Aventy 100 mg is highly bound to plasma proteins and is not significantly eliminated in the urine.

Storage Conditions

Store at 20-25°C

Use In Special Populations

Pediatric Use: STENDRA is not indicated for use in pediatric patients. Safety and efficacy in patients below the age of 18 years has not been established.Geriatric Use: Of the total number of subjects in clinical studies of Aventy 100 mg, approximately 23% were 65 and over. No overall differences in efficacy and safety were observed between subjects over 65 years of age compared to younger subjects; therefore no dose adjustment is warranted based on age alone. However, a greater sensitivity to medication in some older individuals should be considered Renal & hepatic impairment patients: Do not use in patients with severe renal & hepatic impairment

Drug Classes

Drugs for Erectile Dysfunction

Mode Of Action

Aventy 100 mg is a selective phosphodiesterase 5 (PDE5) enzyme inhibitor used for the treatment of erectile dysfunction caused by diabetes, age induced oxidative stress or other complications. Aventy 100 mg inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by Aventy 100 mg enhances erectile function by increasing the amount of cGMP.

Pregnancy

Pregnancy Category C. Aventy 100 mg is not indicated for use in women. There are no adequate and well-controlled studies of Aventy 100 mg in pregnant women.

Pediatric Uses

Frequently Asked Questions

What is Aventy 100 mg used for?

Avanafil is a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction

What is the dosage of Aventy 100 mg?

For most patients, the starting dose is 100 mg taken approximately 30 minutes before sexual activity, on an as needed basis. Avanafil may be taken with or without food. Take Avanafil no more than once a dayThe dose may be increased to 200 mg or decreased to 50 mg based on efficacy and/or tolerability. Use the lowest dose that provides benefitDo not use Avanafil with strong CYP3A4 inhibitors. If ta…

What are the side effects of Aventy 100 mg?

Most common adverse reactions (greater than or equal to 2%) include headache, flushing, nasal congestion, nasopharyngitis, and back pain

Who should not take Aventy 100 mg?

Administration of Avanafil to patients using any form of organic nitrate is contraindicated. Hypersensitivity to any component of the Avanafil tablet

What precautions should be taken with Aventy 100 mg?

Patients should not use Avanafil if sexual activity is inadvisable due to cardiovascular status or any other reason Use of Avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotensionPatients should seek emergency treatment if an erection lasts greater than 4 hoursPatients should stop Avanafil and seek medical care if a sud…

Is Aventy 100 mg safe during pregnancy and breastfeeding?

Pregnancy Category C. Avanafil is not indicated for use in women. There are no adequate and well-controlled studies of Avanafil in pregnant women.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.