10% Off
Nebita Plus5 mg+12.5
Square Pharmaceuticals PLC.
৳108.00
Add to cart
Bipinor Plus5 mg+12.5 mg
Tablet
By
Best PriceTk /
1
Medicine overview
Indications of Bipinor Plus 5 mg+12.5 mg
Essential hypertension
Theropeutic Class
Combined antihypertensive preparations
Pharmacology
The Combination of these ingredients has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone.
Absorption
This combination has mild vasodilating properties which reduces heart rate and blood pressure in hypertensive patients.
Distribution
The diuretic action of Hydrochlorothiazide reduces plasma volume, increases plasma renin activity and increases aldosterone secretion.
Excretion
Hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption which directly increase the excretion of sodium and chloride in approximately equivalent amounts.
Dosage & Administration of Bipinor Plus 5 mg+12.5 mg
Once daily, preferably at the same time every day.
Dosage of Bipinor Plus 5 mg+12.5 mg
Once daily, preferably at the same time every day.
Interaction of Bipinor Plus 5 mg+12.5 mg
Nebivolol:
Class I & III Antiarrhythmics, Calcium channel blocker (Verapamil/Diltiazem)
Centrally-acting antihypertensives, Anaesthetics
Antipsychotics, Antidepressants, NSAIDs
Hydrochlorothiazide:
Drugs affecting Potassium & Calcium level
Non-steroidal anti-inflammatory drugs (NSAIDs)
Concomitant administration of this combination with Antipsychotics, Tricyclic Antidepressants & Barbiturates may enhance the hypotensive effect and lead to postural hypotension.
Contraindications
Hypersensitivity to the active substances, Liver function impairment. Severe renal insufficiency (Creatinine clearance < 30 ml/min.), Bradycardia, Hypotension
Side Effects of Bipinor Plus 5 mg+12.5 mg
Nebivolol: Headache, Dizziness, Tiredness, Diarrhoea, Constipation, Nausea etc.Hydrochlorothiazide: Vertigo, Itchiness, Rash, Increased sensitivity of skin to sunlight etc.
Pregnancy & Lactation
This combination is not recommended during pregnancy. It is also not recommended for mothers who are breast-feeding
Precautions & Warnings
Nebivolol: Beta-blockers should not be used in patients with untreated Congestive Heart Failure (CHF) & bradycardia. In patients with Chronic Obstructive Pulmonary Diseases (COPD), beta-blockers should be used with caution as airway constriction may be aggravated.Hydrochlorothiazide: In patients with renal disease, thiazides may increase azotaemia. If progressive renal impairment becomes evident, careful reappraisal of therapy is necessary. Thiazides can cause fluid or electrolyte imbalance. Thiazides may decrease urinary calcium excretion and may cause slight elevation of serum calcium in the absence of known disorders of calcium metabolism
Overdose Effects of Bipinor Plus 5 mg+12.5 mg
No data are available on Overdosage. Overdosage with Hydrochlorothiazide is associated with electrolyte depletion and dehydration resulting from excessive diuresis.
Storage Conditions
Protect from light & moisture. Store below 30° C. Keep out of reach of children.
Use In Special Populations
Use in children is not recommended.
Drug Classes
Combined antihypertensive preparations
Mode Of Action
The Combination of these ingredients has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone. This combination has mild vasodilating properties which reduces heart rate and blood pressure in hypertensive patients. Hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption which directly increase the excretion of sodium and chloride in approximately equivalent amounts. The diuretic action of Hydrochlorothiazide reduces plasma volume, increases plasma renin activity and increases aldosterone secretion.
Pregnancy
This combination is not recommended during pregnancy. It is also not recommended for mothers who are breast-feeding
Pediatric Uses
Use in children is not recommended.
Frequently Asked Questions
What is Bipinor Plus 5 mg+12.5 mg used for?
Essential hypertension
What is the dosage of Bipinor Plus 5 mg+12.5 mg?
Once daily, preferably at the same time every day.
What are the side effects of Bipinor Plus 5 mg+12.5 mg?
Nebivolol: Headache, Dizziness, Tiredness, Diarrhoea, Constipation, Nausea etc.Hydrochlorothiazide: Vertigo, Itchiness, Rash, Increased sensitivity of skin to sunlight etc.
Who should not take Bipinor Plus 5 mg+12.5 mg?
Hypersensitivity to the active substances, Liver function impairment. Severe renal insufficiency (Creatinine clearance < 30 ml/min.), Bradycardia, Hypotension
What precautions should be taken with Bipinor Plus 5 mg+12.5 mg?
Nebivolol: Beta-blockers should not be used in patients with untreated Congestive Heart Failure (CHF) & bradycardia. In patients with Chronic Obstructive Pulmonary Diseases (COPD), beta-blockers should be used with caution as airway constriction may be aggravated.Hydrochlorothiazide: In patients with renal disease, thiazides may increase azotaemia. If progressive renal impairment becomes evident, …
Is Bipinor Plus 5 mg+12.5 mg safe during pregnancy and breastfeeding?
This combination is not recommended during pregnancy. It is also not recommended for mothers who are breast-feeding
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.