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Citrosol(1500 mg+250 mg)/5 ml
Oral Solution
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Medicine overview
Indications of Citrosol (1500 mg+250 mg)/5 ml
This preparation is indicated in the following cases:
To relieve discomfort in urinary tract infections
To prevent kidney stone
With uricosuric agent to prevent gout
Acidosis caused by kidney diseases
Theropeutic Class
Prevention of repeated kidney stone formation, Urinary Alkalinizing Agent
Pharmacology
Potassium Citrate is absorbed and metabolized to Potassium Bicarbonate, thus acting as a systemic alkalinizer.
Absorption
The effects are essentially those of chlorides before absorption and those of bicarbonates subsequently.
Metabolism
Oxidation is virtually complete so that less than 5% of the Potassium Citrate is excreted in the urine unchanged.
Excretion
Oxidation is virtually complete so that less than 5% of the Potassium Citrate is excreted in the urine unchanged. It alkalinizes the urine without producing a systemic alkalosis in recommended dosage.
Dosage & Administration of Citrosol (1500 mg+250 mg)/5 ml
Notes:This oral Solution should be taken diluted in water according to directions, followed by additional water, if desired. Palatability is enhanced if chilled before taking. Proper dilution may help prevent gastrointestinal injury associated with the oral ingestion of concentrated potassium salt preparations
To relieve discomfort in UTI
Dosage:Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water
Children 1-6 years
Dosage:5 ml 3 times daily, diluted with ½ glass of water
Notes:To prevent kidney stones & acidosis caused by kidney diseases: Adults: 10-15 ml 4 times daily (or as directed by the physician) diluted with 1 glass of water
Children
Dosage:5-10 ml 4 times daily (or as directed by the physician) diluted with ½ glass of water
In gout therapy (with uricosuric agent)
Dosage:Adults: 10-15 ml 4 times daily (or as directed by the physician), diluted with 1 glass of water
Children
Dosage:5-10 ml 4 times daily (or as directed by the physician), diluted with ½ glass of water
| Condition | Dosage | Notes |
|---|---|---|
| This oral Solution should be taken diluted in water according to directions, followed by additional water, if desired. Palatability is enhanced if chilled before taking. Proper dilution may help prevent gastrointestinal injury associated with the oral ingestion of concentrated potassium salt preparations | ||
| To relieve discomfort in UTI | Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water | |
| Children 1-6 years | 5 ml 3 times daily, diluted with ½ glass of water | To prevent kidney stones & acidosis caused by kidney diseases: Adults: 10-15 ml 4 times daily (or as directed by the physician) diluted with 1 glass of water |
| Children | 5-10 ml 4 times daily (or as directed by the physician) diluted with ½ glass of water | |
| In gout therapy (with uricosuric agent) | Adults: 10-15 ml 4 times daily (or as directed by the physician), diluted with 1 glass of water | |
| Children | 5-10 ml 4 times daily (or as directed by the physician), diluted with ½ glass of water |
Dosage of Citrosol (1500 mg+250 mg)/5 ml
To relieve discomfort in UTI
Dosage:Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water
Children 1-6 years
Dosage:5 ml 3 times daily, diluted with ½ glass of water
Notes:To prevent kidney stones, With a uricosuric agent to prevent gout, Acidosis caused by kidney diseases: Adults: 10-15 ml 4 times daily (or as directed by the physician) diluted with 1 glass of water
Pediatric
Dosage:5-10 ml 4 times daily (or as directed by the physician) diluted with ½ glass of water
| Condition | Dosage | Notes |
|---|---|---|
| To relieve discomfort in UTI | Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water | |
| Children 1-6 years | 5 ml 3 times daily, diluted with ½ glass of water | To prevent kidney stones, With a uricosuric agent to prevent gout, Acidosis caused by kidney diseases: Adults: 10-15 ml 4 times daily (or as directed by the physician) diluted with 1 glass of water |
| Pediatric | 5-10 ml 4 times daily (or as directed by the physician) diluted with ½ glass of water |
Interaction of Citrosol (1500 mg+250 mg)/5 ml
Concurrent administration of potassium-containing medication, potassium-sparing diuretics, angiotensin-converting enzyme (ACE) inhibitors or cardiac glycosides may lead to toxicity.
Contraindications
The drug is contraindicated in severe renal impairment with oliguria or azotemia, untreated Addison's disease, acute dehydration, severe myocardial damage and hyperkalemia from any cause.
Side Effects of Citrosol (1500 mg+250 mg)/5 ml
This solution is generally well tolerated without any unpleasant side effect when given in recommended doses to patients with normal renal function and urinary output. However, as with any alkalinizing agent, caution must be used in certain patients with abnormal renal mechanisms to avoid development of hyperkalemia or alkalosis. Potassium intoxication causes listlessness, weakness, mental confusion, tingling of extremities and other symptoms associated with a high concentration of Potassium in the serum.
Pregnancy & Lactation
Combination of Potassium Citrate & Citric Acid Monohydrate should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus. It is not known if this drug is found in breast milk or not. Breast-feeding women should consult with their health care provider to confirm about taking this drug.
Precautions & Warnings
The solution should be used with caution in patients with low urinary output. It should be diluted adequately with water to minimize the possibility of gastrointestinal injury associated with the oral ingestion of concentrated Potassium salt preparations; and preferably, to take each dose after meals. Large doses may cause hyperkalemia and alkalosis, especially in the presence of renal disease.
Overdose Effects of Citrosol (1500 mg+250 mg)/5 ml
The administration of oral Potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, hyperkalemia can result. Hyperkalemia, when detected, must be treated immediately because lethal levels can be reached in a few hours. If hyperkalemia occurs, treatment measures will include the followings: (1) Elimination of foods or medications containing potassium. (2) The intravenous administration of 300 to 500 ml/hr of dextrose solution (10 to 25%), containing 10 units of insulin/20 gm dextrose. (3) The use of exchange resins, hemodialysis or peritoneal dialysis.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Classes
Prevention of repeated kidney stone formation, Urinary Alkalinizing Agent
Mode Of Action
Potassium Citrate and Citric Acid oral solution is a stable and pleasant-tasting oral systemic alkalizer. Potassium Citrate is absorbed and metabolized to Potassium Bicarbonate, thus acting as a systemic alkalizer. This product alkalinizes the urine without producing a systemic alkalosis in recommended doses. It is highly palatable, pleasant tasting and tolerable, even when administered for long periods. Potassium Citrate does not neutralize the gastric juice or disturb digestion.
Pregnancy
No information is available regarding the use of this drug during pregnancy and lactation.
Frequently Asked Questions
What is Citrosol (1500 mg+250 mg)/5 ml used for?
This preparation is indicated in the following cases: To relieve discomfort in urinary tract infections To prevent kidney stone With uricosuric agent to prevent gout Acidosis caused by kidney diseases
What is the dosage of Citrosol (1500 mg+250 mg)/5 ml?
To relieve discomfort in UTI: Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water. Children 1-6 years: 5 ml 3 times daily, diluted with ½ glass of water. To prevent kidney stones, With a uricosuric agent to prevent gout, Acidosis caused by kidney diseases: Adults: 10-15 ml 4 times daily (or as directed by the physician) diluted with 1 glass of water. Pediatric: 5-1…
What are the side effects of Citrosol (1500 mg+250 mg)/5 ml?
This solution is generally well tolerated without any unpleasant side effect when given in recommended doses to patients with normal renal function and urinary output. However, as with any alkalinizing agent, caution must be used in certain patients with abnormal renal mechanisms to avoid development of hyperkalemia or alkalosis. Potassium intoxication causes listlessness, weakness, mental confusi…
Who should not take Citrosol (1500 mg+250 mg)/5 ml?
The drug is contraindicated in severe renal impairment with oliguria or azotemia, untreated Addison's disease, acute dehydration, severe myocardial damage and hyperkalemia from any cause.
What precautions should be taken with Citrosol (1500 mg+250 mg)/5 ml?
The solution should be used with caution in patients with low urinary output. It should be diluted adequately with water to minimize the possibility of gastrointestinal injury associated with the oral ingestion of concentrated Potassium salt preparations; and preferably, to take each dose after meals. Large doses may cause hyperkalemia and alkalosis, especially in the presence of renal disease.
Is Citrosol (1500 mg+250 mg)/5 ml safe during pregnancy and breastfeeding?
Combination of Potassium Citrate & Citric Acid Monohydrate should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus. It is not known if this drug is found in breast milk or not. Breast-feeding women should consult with their health care provider to confirm about taking this drug.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.