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Comfil2 mg
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Medicine overview
Indications of Comfil 2 mg
Comfil 2 mg is indicated for the treatment and prevention of bronchospasm in adultsadolescents & children of 6 years of age and older with reversible obstructive airway diseases.
Theropeutic Class
Short-acting selective & β2-adrenoceptor stimulants
Pharmacology
Comfil 2 mg is a single isomer beta-2 agonist that differs from racemic salbutamol by elimination of (S)-salbutamol.
Absorption
Comfil 2 mg is an effective bronchodilator whose primary mechanism of action is not inhibited by (S)-salbutamol.
Distribution
Thus, when compared with racemic salbutamol, clinically comparable bronchodilation can be achieved.
Metabolism
Comfil 2 mg produces bronchodilatation through stimulation of beta-2-adrenergic receptors in bronchial smooth muscles, thereby causing relaxation of bronchial muscle fibres.
Dosage & Administration of Comfil 2 mg
Children (6 -11 years)
Dosage:5 ml (1 mg), three times daily
Adults and adolescents above 12 years
Dosage:5-10 ml (1-2 mg), three times daily
| Condition | Dosage | Notes |
|---|---|---|
| Children (6 -11 years) | 5 ml (1 mg), three times daily | |
| Adults and adolescents above 12 years | 5-10 ml (1-2 mg), three times daily |
Interaction of Comfil 2 mg
Other short-acting sympathomimetic bronchodilators or epinephrine should be used with caution with Comfil 2 mg. If additional adrenergic drugs are to be administered by any route, they should be used with caution to avoid deleterious cardiovascular effects.
Contraindications
Comfil 2 mg is contraindicated in patients with a history of hypersensitivity to Comfil 2 mg or any of its components.
Side Effects of Comfil 2 mg
Hypocalcaemia, palpitation, fine tremors of the skeletal muscle and muscle cramps may occur. The other likely side effects are nausea, vomiting, epigastric pain and diarrhoea.
Pregnancy & Lactation
The drug should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus. It is not known whether Comfil 2 mg is excreted in human milk. Caution should be exercised when oral Comfil 2 mg is administered to a nursing woman.
Precautions & Warnings
Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia and by concomitant treatment with xanthine derivatives, steroids and diuretics. Serum potassium levels should be monitored in such situations.
Storage Conditions
Keep in dry place and away from light and heat. Keep out of the reach of children.
Frequently Asked Questions
What is Comfil 2 mg used for?
Levosalbutamol is indicated for the treatment and prevention of bronchospasm in adults, adolescents & children of 6 years of age and older with reversible obstructive airway diseases.
What is the dosage of Comfil 2 mg?
Children (6 -11 years): 5 ml (1 mg), three times daily.Adults and adolescents above 12 years: 5-10 ml (1-2 mg), three times daily.
What are the side effects of Comfil 2 mg?
Hypocalcaemia, palpitation, fine tremors of the skeletal muscle and muscle cramps may occur. The other likely side effects are nausea, vomiting, epigastric pain and diarrhoea.
Who should not take Comfil 2 mg?
Levosalbutamol is contraindicated in patients with a history of hypersensitivity to Levosalbutamol or any of its components.
What precautions should be taken with Comfil 2 mg?
Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia and by concomitant treatment with xanthine derivatives, steroids and diuretics. Serum potassium levels should be monitored in such situations.
Is Comfil 2 mg safe during pregnancy and breastfeeding?
The drug should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus. It is not known whether levosalbutamol is excreted in human milk. Caution should be exercised when oral levosalbutamol is administered to a nursing woman.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.