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Cyclid5 mg
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Medicine overview
Indications of Cyclid 5 mg
Procyclidine is used for the adjunctive treatment of all forms of parkinsonian syndrome. It is mainly used for the symptomatic treatment of idiopathic (paralysis agitants), postencephalitic and arteriosclerotic parkinsonian. It is used to control troublesome extrapyramidal symptoms including pseudoparkinsonian ... Read moreProcyclidine is used for the adjunctive treatment of all forms of parkinsonian syndrome. It is mainly used for the symptomatic treatment of idiopathic (paralysis agitants), postencephalitic and arteriosclerotic parkinsonian. It is used to control troublesome extrapyramidal symptoms including pseudoparkinsonian, acute dystonic reactions and akathisia induced by neuroleptic drugs such as phenothiazine derivatives.
Theropeutic Class
Antiparkinson drugs
Pharmacology
Procyclidine hydrochloride is an antimuscarinic antiparkinsonian agent of relatively low toxicity.
Absorption
It is absorbed from G.
Distribution
tract and disappears rapidly from the tissues.
Metabolism
After intravenous administration, it acts within 5 to 20 minutes and has a duration of effect up to 4 hours.
Dosage & Administration of Cyclid 5 mg
Oral administration
Dosage:Adults: Procyclidine tablet is administered orally, preferably after meals
Parkinsonism
Dosage:Initially 2.5 mg 3 times a day, then 5 mg 3 times a day and occasionally 5 mg at bed time
Notes:The dosage being adjusted as tolerated or until the total daily dose reaches 20 to 30 mg divided into 3 to 4 doses
Drug induced extrapyramidal symptom
Dosage:Initially 2.5 mg 3 times a day
Notes:The dosage being increased by 2.5 mg increment per day as needed and tolerated
Children
Dosage:Safety and efficacy have not been established in the pediatric age group; therefore, the use of Cyclid 5 mg in this age group requires that the potential benefits be weighed against the possible hazards to children
IM or IV administration
Dosage:By intramuscular or intravenous injection, 5-10 mg, repeated if necessary after 20 minutes; maximum 20 mg daily can be given
| Condition | Dosage | Notes |
|---|---|---|
| Oral administration | Adults: Procyclidine tablet is administered orally, preferably after meals | |
| Parkinsonism | Initially 2.5 mg 3 times a day, then 5 mg 3 times a day and occasionally 5 mg at bed time | The dosage being adjusted as tolerated or until the total daily dose reaches 20 to 30 mg divided into 3 to 4 doses |
| Drug induced extrapyramidal symptom | Initially 2.5 mg 3 times a day | The dosage being increased by 2.5 mg increment per day as needed and tolerated |
| Children | Safety and efficacy have not been established in the pediatric age group; therefore, the use of Cyclid 5 mg in this age group requires that the potential benefits be weighed against the possible hazards to children | |
| IM or IV administration | By intramuscular or intravenous injection, 5-10 mg, repeated if necessary after 20 minutes; maximum 20 mg daily can be given |
Dosage of Cyclid 5 mg
Tablet
Dosage:This is administered orally, preferably after meals
Parkinsonism
Dosage:Initially 2.5 mg 3 times a day, then 5 mg 3 times a day and occasionally 5 mg at bedtime
Notes:The dosage being adjusted as tolerated or until the total daily dose reaches 20 to 30 mg divided into 3 to 4 doses
Drug induced extrapyramidal symptom
Dosage:Initially 2.5 mg 3 times a day
Notes:The dosage being increased by 2.5 mg increment per day as needed and tolerated
IM or IV injection
Dosage:5-10 mg, repeated if necessary after 20 minutes; maximum 20 mg daily can be given
| Condition | Dosage | Notes |
|---|---|---|
| Tablet | This is administered orally, preferably after meals | |
| Parkinsonism | Initially 2.5 mg 3 times a day, then 5 mg 3 times a day and occasionally 5 mg at bedtime | The dosage being adjusted as tolerated or until the total daily dose reaches 20 to 30 mg divided into 3 to 4 doses |
| Drug induced extrapyramidal symptom | Initially 2.5 mg 3 times a day | The dosage being increased by 2.5 mg increment per day as needed and tolerated |
| IM or IV injection | 5-10 mg, repeated if necessary after 20 minutes; maximum 20 mg daily can be given |
Interaction of Cyclid 5 mg
The anticholinergic activity of procyclidine may be increased by agents having anticholinergic amantadine. The absorption of ketoconazole may be reduced by concomitant administration of procyclidine.
Contraindications
It should be given with caution in children and geriatric patients. It is advisable to be cautious in giving Procyclidine to patients with diarrhoea and cardiovascular disease, glaucoma, urinary retention, hepatic or renal impairment. The safety of using procyclidine during pregnancy has not been established. No data are available on the excretion of this drug in breast milk.
Side Effects of Cyclid 5 mg
At usual dosage levels dryness of the mouth is generally the only adverse effect. Mydriasis, blurred vision and adverse G.I. effects (nausea, vomiting, epigastric distress, constipation) occur occasionally. An allergic reaction (e.g. rash) or muscular weakness may occasionally occur. High doses may cause vertigo and possibly confusion and hallucination. Adverse effect may usually be minimized by adjustment of dosage and administration after meal.
Pregnancy & Lactation
The safe use of this drug in pregnancy, lactation or in women of childbearing age requires that the potential benefits be weighed against the possible hazards to the mother and child.
Precautions & Warnings
Precaution should be taken in case of hepatic & renal impairment, children, elderly, pregnancy and lactation condition. Patients with mental disorders occasionally experience a precipitation of a psychotic episode when Procyclidine is administered for the treatment of the extrapyramidal side-effects of neuroleptic. Procyclidine should not be withdrawn abruptly as rebound Parkinsonism symptoms may occur.
Storage Conditions
Protect from light and moisture, store below 25°C. Keep out of the reach of children.
Drug Classes
Antiparkinson drugs
Mode Of Action
Procyclidine hydrochloride is an antimuscarinic antiparkinsonian agent of relatively low toxicity. It is a synthetic tertiary amine. This drug exerts their antiparkinsonian effect by correcting the relative cholinergic excess which is thought to occur in parkinsonian as a result of dopamine deficiency. It is absorbed from G.I. tract and disappears rapidly from the tissues. After intravenous administration, it acts within 5 to 20 minutes and has a duration of effect up to 4 hours.
Pregnancy
The safe use of this drug in pregnancy, lactation or in women of childbearing age requires that the potential benefits be weighed against the possible hazards to the mother and child.
Pediatric Uses
Use in children: Safety and efficacy have not been established in the pediatric age group; therefore the use of Procyclidine hydrochloride is this group requires that the potential benefits be weighed against the possible hazards to children.
Frequently Asked Questions
What is Cyclid 5 mg used for?
Procyclidine is used for the adjunctive treatment of all forms of parkinsonian syndrome. It is mainly used for the symptomatic treatment of idiopathic (paralysis agitants), postencephalitic and arteriosclerotic parkinsonian. It is used to control troublesome extrapyramidal symptoms including pseudoparkinsonian ... Read moreProcyclidine is used for the adjunctive treatment of all forms of parkinson…
What is the dosage of Cyclid 5 mg?
Tablet: This is administered orally, preferably after meals. Parkinsonism: Initially 2.5 mg 3 times a day, then 5 mg 3 times a day and occasionally 5 mg at bedtime. The dosage being adjusted as tolerated or until the total daily dose reaches 20 to 30 mg divided into 3 to 4 doses. Drug induced extrapyramidal symptom: Initially 2.5 mg 3 times a day. The dosage being increased by 2.5 mg increment per…
What are the side effects of Cyclid 5 mg?
At usual dosage levels dryness of the mouth is generally the only adverse effect. Mydriasis, blurred vision and adverse G.I. effects (nausea, vomiting, epigastric distress, constipation) occur occasionally. An allergic reaction (e.g. rash) or muscular weakness may occasionally occur. High doses may cause vertigo and possibly confusion and hallucination. Adverse effect may usually be minimized by a…
Who should not take Cyclid 5 mg?
It should be given with caution in children and geriatric patients. It is advisable to be cautious in giving Procyclidine to patients with diarrhoea and cardiovascular disease, glaucoma, urinary retention, hepatic or renal impairment. The safety of using procyclidine during pregnancy has not been established. No data are available on the excretion of this drug in breast milk.
What precautions should be taken with Cyclid 5 mg?
Precaution should be taken in case of hepatic & renal impairment, children, elderly, pregnancy and lactation condition. Patients with mental disorders occasionally experience a precipitation of a psychotic episode when Procyclidine is administered for the treatment of the extrapyramidal side-effects of neuroleptic. Procyclidine should not be withdrawn abruptly as rebound Parkinsonism symptoms may …
Is Cyclid 5 mg safe during pregnancy and breastfeeding?
The safe use of this drug in pregnancy, lactation or in women of childbearing age requires that the potential benefits be weighed against the possible hazards to the mother and child.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.