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Cefexta125 mg/5 m
Cefdinir
Unimed Unihealth MFG. Ltd.
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Efdinir125 mg/5 ml
Powder for Suspension
Cefdinir
Incepta Pharmaceuticals Ltd.
Product Code : 5593
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Medicine overview
Indications of Efdinir 125 mg/5 ml
Efdinir 125 mg/5 ml is indicated for the treatment of Community Acquired Pneumonia, Acute Exacerbation of Chronic Bronchitis, Acute Maxillary Sinusitis, Pharyngitis, Tonsillitis, Uncomplicated Skin and Skin Structure, Infections
Theropeutic Class
Third generation Cephalosporins
Pharmacology
Efdinir 125 mg/5 ml binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Dosage & Administration of Efdinir 125 mg/5 ml
Adult: 600 mg daily as a single or in 2 divided doses for 5-10 days.Child: ≥6 months: 14 mg/kg daily as a single or in 2 divided doses. Max: 600 mg daily.
Dosage of Efdinir 125 mg/5 ml
Adult: 600 mg daily as a single or in 2 divided doses for 5-10 days.Child: ≥6 months: 14 mg/kg daily as a single or in 2 divided doses. Max: 600 mg daily.
Interaction of Efdinir 125 mg/5 ml
Antacids: Efdinir 125 mg/5 ml should be taken at least 2 hours interval of antacid administration.Iron supplement: Efdinir 125 mg/5 ml should be taken at least 2 hours interval of iron supplement administration.Probencid: It inhibits the renal excretion of Efdinir 125 mg/5 ml.
Contraindications
Efdinir 125 mg/5 ml is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.
Side Effects of Efdinir 125 mg/5 ml
Common side effects are Diarrhea, Vaginal moniliasis, Nausea & Vomiting, Headache, Rash etc.
Pregnancy & Lactation
Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Following administration of single 600 mg doses, Efdinir 125 mg/5 ml was not detected in human breast milk.
Precautions & Warnings
Efdinir 125 mg/5 ml, as with other broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis. In patients with transient or persistent renal insufficiency (creatinine clearance <30 ml/min), the total daily dose of Efdinir 125 mg/5 ml should be reduced.
Overdose Effects of Efdinir 125 mg/5 ml
Symptoms: Nausea, vomiting, epigastric distress, diarrhoea, convulsions. Management: Haemodialysis may be useful in the event of a serious toxic reaction particularly if renal function is compromised.
Storage Conditions
Store between 20-25° C.
Drug Classes
Third generation Cephalosporins
Mode Of Action
Efdinir 125 mg/5 ml binds to 1 or more of the penicillin-binding proteins (PBPs) which inhibit the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Pregnancy
Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Following administration of single 600 mg doses, Efdinir 125 mg/5 ml was not detected in human breast milk.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.
