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Oradin

Oradin60 ml

Oral Suspension

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Medicine overview

Indications of Oradin 60 ml

Oradin 60 ml tablet provides fasteffective relief from the symptoms of seasonal allergic rhinitisnasal dischargeitchingocular itching ... Read moreOradin 60 ml tablet provides fasteffective relief from the symptoms of seasonal allergic rhinitisnasal dischargeitchingnettlerash.

Theropeutic Class

Non-sedating antihistamines

Pharmacology

Oradin 60 ml is a tricyclic antihistamine with selective peripheral histamine H1-receptor antagonistic activity.

Absorption

It is devoid of anticholinergic activity.

Distribution

It is rapidly effective and long-lasting, allowing once-a-day administration.

Dosage & Administration of Oradin 60 ml

Adults and children (6 years of age and over)
Dosage:10 mg daily (1 tablet or 2 teaspoonfuls of syrup) once daily
Children ( 2 to 5 years of age)
Dosage:5 mg (1 teaspoonful syrup) once daily

Dosage of Oradin 60 ml

Adults and children over 12 years of age
Dosage:One Oradin 60 ml tablet once daily
Notes:It is usually administered in the morning or when symptoms require treatment
Children 2-12 years
Dosage:Body weight over 30 kg: one Oradin 60 ml tablet once daily, below 30 kg: half Oradin 60 ml tablet once daily
Below 2 years of age
Dosage:Oradin 60 ml tablet is not recommended for use below 2 years of age since safety and efficacy has not been established

Interaction of Oradin 60 ml

There are no reports of potentially hazardous interactions with other drugs. In contrast to many other histamine H1 receptor antagonists, Oradin 60 ml has no potentiating effects when administered concurrently with alcohol, as measured by psychomotor performance studies. Concomitant therapy with drugs that inhibit or are metabolized by hepatic cytochromes P450 3A4 and 2D6 may elevate plasma concentrations of either drug and this mayifesult in adverse effects. Cimetidine inhibits both enzymes while erythromycin or ketoconazole inhibits P450 3A4. These drugs increase Oradin 60 ml serum concentrations but no adverse effects are reported.

Contraindications

Oradin 60 ml is contraindicated in patients who have shown hypersensitivity or idiosyncrasy to their components.

Side Effects of Oradin 60 ml

During controlled clinical studies the incidence of adverse events, including sedation and anticholinergic effects observed with 10 mg Oradin 60 ml was comparable to that observed with placebo. Studies on the effect of Oradin 60 ml on actual driving performance, and on tests of cognitive and psychomotor functioning have shown it to be comparable to placebo.

Pregnancy & Lactation

US FDA Pregnancy Category of Oradin 60 ml is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Oradin 60 ml have been shown to be excreted in human milk. So, caution should be exercised when Oradin 60 ml is administered to a nursing woman.

Precautions & Warnings

Caution should be taken in patients with liver impairment or renal insufficiency (eGFR <30 ml/min).

Overdose Effects of Oradin 60 ml

In adults somnolence, tachycardia and headache have been reported with overdose greater than 10 mg. Extrapyramidal signs and palpitations have been reported in children with overdoses of greater than 10 mg. In the event of overdosage, general symptomatic and supportive measures should be instituted promptly and maintained for as long as necessary. It would seem reasonable to treat patients presenting early after large overdoses with oral activated charcoal. The conscious patients may be induced to vomit or gastric lavage may be performed.

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

Drug Classes

Non-sedating antihistamines

Mode Of Action

This tablet is a preparation of Oradin 60 ml. Oradin 60 ml is a non-sedative histamine Hr receptor antagonist with antiallergic properties. Oradin 60 ml is a long-acting tricyclic antihistamine with selective peripheral Hi-receptor antagonistic activity and no central sedative or anticholinergic effect. It is rapidly effective and long-lasting, allowing once-a-day administration.

Pregnancy

There is no experience of the use of Oradin 60 ml in human pregnancy. Therefore its use during pregnancy is not advisable. Oradin 60 ml is excreted in breast milk in a very small amount. So nursing mothers are advised not to take the drug.

Frequently Asked Questions

What is Oradin 60 ml used for?

Loratadine tablet provides fast, effective relief from the symptoms of seasonal allergic rhinitis, perennial allergic rhinitis and skin allergies including chronic urticaria. It is also effective in alleviating symptoms of allergic rhinitis such as sneezing, nasal discharge, itching, ocular itching ... Read moreLoratadine tablet provides fast, effective relief from the symptoms of seasonal allergi…

What is the dosage of Oradin 60 ml?

Adults and children over 12 years of age: One Loratadine tablet once daily. It is usually administered in the morning or when symptoms require treatment.Children 2-12 years: Body weight over 30 kg: one Loratadine tablet once daily, below 30 kg: half Loratadine tablet once daily.Below 2 years of age: Loratadine tablet is not recommended for use below 2 years of age since safety and efficacy has not…

What are the side effects of Oradin 60 ml?

During controlled clinical studies the incidence of adverse events, including sedation and anticholinergic effects observed with 10 mg Loratadine was comparable to that observed with placebo. Studies on the effect of Loratadine on actual driving performance, and on tests of cognitive and psychomotor functioning have shown it to be comparable to placebo.

Who should not take Oradin 60 ml?

Loratadine is contraindicated in patients who have shown hypersensitivity or idiosyncrasy to their components.

What precautions should be taken with Oradin 60 ml?

Caution should be taken in patients with liver impairment or renal insufficiency (eGFR <30 ml/min).

Is Oradin 60 ml safe during pregnancy and breastfeeding?

US FDA Pregnancy Category of Loratadine is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Loratadine have been shown to be excreted in human milk. So, caution should be exercised when Loratadine is administered to a nu…

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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